Empowering young athletes: the influence of autonomy-supportive coaching on resilience, optimism, and development.

Introduction: The present study investigates how autonomy-supportive coaching style influences youth athlete development through psychological resilience and dispositional optimism. Despite growing interest in factors that contribute to athlete development, gaps remain in understanding how coaching approaches interact with psychological traits to foster youth athletes' growth. This study addresses these gaps by proposing a serial mediation model in which autonomy-supportive coaching indirectly enhances athlete development through resilience and optimism.

Multipronged impact of environmental temperature on Staphylococcus aureus infection by phage Kayvirus rodi: Implications for biofilm control.

Environmental cues sometimes have a direct impact on phage particle stability, as well as bacterial physiology and metabolism, having a profound effect on phage infection outcome. Here, we explore the impact of temperature on the interplay between phage (phiIPLA-RODI) and its host, . Our results show that phiIPLA-RODI is a more effective predator at room (25 °C) compared to body temperature (37 °C) against planktonic cultures of several strains with varying degrees of phage susceptibility.

Zebrafish PEX1 Is Required for the Generation of GABAergic Neuron in p3 Domain.

Maintenance of neural progenitors requires Notch signaling in vertebrate development. Previous study has shown that Jagged2-mediated Notch signaling maintains proliferating neural progenitors in the ventral spinal cord. However, components for Jagged-mediated signaling remain poorly defined during late neurogenesis.

Development of Digestive Tract in Larval and Juvenile Red Spotted Grouper, .

This study investigated the progressive morphological alterations and digestive tract development in larval and juvenile red spotted grouper, across growth stages. External shape observations were made using an optical microscope, and the development of the digestive tract was investigated using histological methods. At 1 day after hatching (DAH), the digestive tract appeared as a straight tube extending between the ventral side and yolk-sac.

Identification of a potential homeodomain-like gene governing leaf size and venation architecture in birch.

Leaf vein, an essential part of leaf architecture, plays significant roles in shaping the proper leaf size. To date, the molecular mechanisms governing leaf development including leaf venation patterning remains poorly understood in birch. Here, we performed the genome-wide identification of homeodomain-like (HD-like) superfamily genes using phylogenetic analysis and revealed the functional role of a potential HD-like gene in leaf growth and development using transgenic technology and transcriptomic sequencing.

Subtilases: a major prospect to the genome editing in horticultural crops.

Plant peptides, synthesized from larger precursor proteins, often undergo proteolytic cleavage and post-translational modifications to form active peptide hormones. This process involves several proteolytic enzymes (proteases). Among these, SBTs (serine proteases) are a major class of proteolytic enzymes in plants and play key roles in various regulatory mechanisms, including plant immune response, fruit development and ripening, modulating root growth, seed development and germination, and organ abscission.

C-type natriuretic peptide promotes human granulosa cell growth and estradiol production: Implications for early follicle development.

Purpose: To investigate the effects of C-type natriuretic peptide (CNP) on human granulosa cell growth and elucidate its regulatory mechanisms.

Methods: A human non-luteinizing granulosa cell line (HGrC) developed from small antral follicles was used to assess the impact of CNP on cell proliferation and estrogen synthesis. cGMP production via the guanylate cyclase domain of the CNP receptor, natriuretic peptide receptor 2 (NPR2), was confirmed.

Image dataset: UAV images and ground data of one 'Bingo' mandarin and two 'Valencia' orange rootstock trials conducted in Florida.

The data are aerial images and ground tree measurement data of 3 citrus rootstock trials. Developing new citrus rootstock varieties requires field trials to test to identify selections with improved horticultural performance. A bud from a scion variety is grafted onto the rootstock and grown in a nursery until the grafted plant is ready to be planted in the field, which is in about one year.

GSAG:Ce scintillator: insights from yttrium admixture.

The GSAG:Ce scintillator represents a promising and cost-effective alternative to the expensive GGAG:Ce. Recent studies have attributed its low light yield to the thermal quenching effect. In this study, we employed the strategy of adding an yttrium (Y) admixture to the GSAG matrix to increase the thermal activation energy of thermal quenching.

Optimization of erythritol production through fermentation using molasses as carbon source.

Erythritol is a beneficial sugar alcohol that can be used as a sugar substitute for diabetic patients. Erythritol is a bioproduct produced by microorganisms as a response to high osmotic pressure and stress in the growth medium. High concentrations of carbon source substrate can increase the osmotic pressure and provide more nutrient supply for yeast growth and metabolism.

A novel sensitizer reduces EGFR-TKI resistance by regulating the PI3K/Akt/mTOR pathway and autophagy.

Background: The incidence and mortality of lung cancer are high, and treatment with epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is the preferred first-line treatment for patients suffering from non-small cell lung cancer (NSCLC) with EGFR mutations. However, EGFR-TKI resistance leads to treatment failure. Yifei-Sanjie pill (YFSJ) is a novel type of Chinese patent medicine for lung cancer.

Flexible modular dwelling for rural environments; specific case: Cebadas - Ecuador.

Background: Sustainable modular dwelling design for rural areas should focus on creating healthy and economically accessible spaces, sensitive to local needs and integrating environmental, functional, sociological and technological aspects. Flexibility is essential to reduce the initial investment and allow future transformations, optimizing the recovery and reuse of materials. These houses must be adaptable, safe and have basic services, satisfying the needs and stages of families' development.

Large Language Models in Healthcare: A Bibliometric Analysis and Examination of Research Trends.

Background: The integration of large language models (LLMs) in healthcare has generated significant interest due to their potential to improve diagnostic accuracy, personalization of treatment, and patient care efficiency.

Objective: This study aims to conduct a comprehensive bibliometric analysis to identify current research trends, main themes and future directions regarding applications in the healthcare sector.

Methods: A systematic scan of publications until 08.

Reflections on microbial genetic resources in agricultural systems.

This paper reflects on the use of microbial genetic resources in the context of agricultural systems. The benefits of harnessing the diversity of these resources in any agricultural system are highlighted, as well as the importance of knowing and preserving native agrobiodiversity, which is deemed an essential resource for Latin America. In this region, harmful effects of irrational use of agrochemicals and monocultures on the environment, economy, and health have been brought to light.

Biofilm architecture and dynamics of the oral ecosystem.

The oral cavity, being a nutritionally enriched environment, has been proven to be an ideal habitat for biofilm development. Various microenvironments, including dental enamel, supra- and subgingival surfaces, salivary fluid, and the dorsal surface of the tongue, harbor diverse microbes. These biofilms typically consist of four major layers.

Exosomes derived from syncytia induced by SARS-2-S promote the proliferation and metastasis of hepatocellular carcinoma cells.

Introduction: Coronavirus disease 2019 (COVID-19) is characterized by fever, fatigue, dry cough, dyspnea, mild pneumonia and acute lung injury (ALI), which can lead to acute respiratory distress syndrome (ARDS), and SARS-CoV-2 can accelerate tumor progression. However, the molecular mechanism for the increased mortality in cancer patients infected with COVID-19 is unclear.

Methods: Colony formation and wound healing assays were performed on Huh-7 cells cocultured with syncytia.

Costs and benefits of maternal nest choice: Trade-offs between brood survival and thermal stress in bees.

Optimal nest site selection is crucial in animals whose offspring are completely dependent on the shelter of a nest. Parental decisions influencing nest thermal conditions are particularly important because temperature strongly influences juvenile activity, metabolism, growth, developmental rate, survival, and adult body size. In small ectotherms such as bees, maternal decisions to nest in sun-exposed or shady sites can lead to marked differences in thermal microenvironments inside nests.

[Research advance of solid-phase microextraction based on covalent organic framework materials].

Solid-phase microextraction (SPME) is a fast and simple sample preparation technique that enables the enrichment of analytes, and it is used in combination with other detection techniques to provide accurate and sensitive analytical methods. SPME is widely used in environmental monitoring, food safety, life analysis, biomedicine, and other applications. The extractive coating is the core of the SPME technique, and the properties of the extractive coating greatly influence extraction selectivity and efficiency, as well as the enrichment effect.

Putting seedlings on the map: Trade-offs in demographic rates between ontogenetic size classes in five tropical forests.

All species must partition resources among the processes that underly growth, survival, and reproduction. The resulting demographic trade-offs constrain the range of viable life-history strategies and are hypothesized to promote local coexistence. Tropical forests pose ideal systems to study demographic trade-offs as they have a high diversity of coexisting tree species whose life-history strategies tend to align along two orthogonal axes of variation: a growth-survival trade-off that separates species with fast growth from species with high survival and a stature-recruitment trade-off that separates species that achieve large stature from species with high recruitment.

Optimized Rutin-incorporating PEGylated Nanoliposomes as a Model wit Remarkable Selectivity Against PANK1 and MCF7 Cell Lines.

Background: This study aims to enhance the delivery of polyphenols using nanotechnology.

Objective: To develop and evaluate liposomal formulations for improved delivery and stability of polyphenols, specifically focusing on Rutin.

Methods: Liposomal formulations were meticulously prepared via the Thin-Film Hydration method.

[Disease burden and clinical status of congenital heart disease combined with heart failure in China: a survey and analysis].

To investigate the disease burden, clinical characteristics and independent risk factors affecting in-hospital outcomes of children with congenital heart disease (CHD) combined with heart failure (HF) in China. (1) Descriptive study: based on the global burden of disease study 2021, available data on children under 15 years of age with CHD and HF in China from 1990 to 2021 were collected. The prevalence and trends in different age subgroups (<1 year, 1-<2 years, 2-<5 years, 5-<10 years, 10-<15 years) were analyzed, and the annual percentage change (EAPC) was estimated using linear regression.

Whole Brain MRI Assessment of Age and Sex-Related R2* Changes in the Human Fetal Brain.

Iron in the brain is essential to neurodevelopmental processes, as it supports neural functions, including processes of oxygen delivery, electron transport, and enzymatic activity. However, the development of brain iron before birth is scarcely understood. By estimating R2* (1/T2*) relaxometry from a sizable sample of fetal multiecho echo-planar imaging (EPI) scans, which is the standard sequence for functional magnetic resonance imaging (fMRI), across gestation, this study investigates age and sex-related changes in iron, across regions and tissue segments.

Impact of Co-doping Eu and Gd in HMO-Based Glasses for Structural and Optical Properties and Radiation Shielding Enhancement.

Eu-Gd co-doped glasses composed of 15BO-12SiO-(40-x)TeO-3EuO-xGdO-12BiO-8BaO-10ZnO with x = 0-4 mol% (coded as EuGd-x) were fabricated using melt quench approach to develop transparent radiation shielding system. Their structural, optical and mechanical properties were examined. 5.

Macranthoside B Suppresses the Growth of Adenocarcinoma of Esophagogastric Junction by Regulating Iron Homeostasis and Ferroptosis through NRF2 Inhibition.

Background: Macranthoside B (MB) is a saponin compound extracted from hon-eysuckle that has been reported to exhibit significant medicinal values, particularly anti-tumor activities. This study aimed to evaluate the anticancer efficacy of MB in treating adenocarci-noma of the esophagogastric junction (AEG) and elucidate its underlying mechanisms.

Methods: Three AEG cell lines and normal gastric epithelial cells were used to assess the an-ticancer activity of MB in vitro.

Therapeutic Potential of Plant Phenolic Acids Combating Cancer Drug Resistance.

Despite notable progress in treatment modalities, cancer continues to be a prom-inent cause of death globally. Chemotherapy is the main method used to treat cancer, and chemotherapeutic medications are categorized according to how they work. Nevertheless, the issue of multidrug resistance (MDR) is a significant obstacle, impacting almost 90% of cancer patients who receive chemotherapy or innovative targeted medicines.