Characteristics of pediatric multiple sclerosis: The Turkish pediatric multiple sclerosis database.

Objective: To document the clinical and paraclinical features of pediatric multiple sclerosis (MS) in Turkey.

Methods: Data of MS patients with onset before age 18 years (n = 193) were collected from 27 pediatric neurology centers throughout Turkey. Earlier-onset (<12 years) and later-onset (≥12 years) groups were compared.

Association of neck circumference and pulmonary function in children.

Background: Childhood obesity leads to many complications including impaired respiratory function. There are various anthropometric parameters related to obesity.

Objective: To investigate the correlation between anthropometric indices and pulmonary function test results in children without asthma.

General and Disease-specific Scales in Children with Asthma and their Parents.

Objective: To investigate and compare the efficiency of general and disease-specific life quality scales in children with asthma.

Methods: Children with asthma, and their parents completed the Childhood Asthma Control Test (C-ACT), Pediatric Asthma Quality of Life Questionnaire (PAQLQ), Pediatric Quality of Life Inventory (PedsQL), and also underwent spirometry.

Results: 82 children (55 males) with a median (IQR) age of 10.

Association of wider neck circumference and asthma in obese children.

Background: Obesity is a well-established risk factor for asthma. Previous studies have reported that central obesity is associated with asthma.

Objective: To investigate the association between fat distribution, which is determined by anthropometric measures, including neck circumference (NC), and asthma in school-aged children.

Low indoleamine 2,3-dioxygenase activity in persistent food allergy in children.

Background: Indoleamine 2,3-dioxygenase (IDO), which degrades tryptophan (Trp) to kynurenine (Kyn), has been demonstrated to contribute to modulation of allergic responses. However, the role of IDO in food allergy has not yet been elucidated.

Methods: Serum Trp and Kyn concentrations were analyzed by high-pressure liquid chromatography.

Wider neck circumference is related to severe asthma in children.

Background: Obesity is an established risk factor for asthma in children. Measures of central obesity are reported to be more associated with the severity of asthma in adults. The aim of the study was to investigate the association between fat distribution, which is determined by anthropometric measures including neck circumference (NC) and asthma severity in children.

Protective Effects of Nigella sativa Oil in Hyperoxia-Induced Lung Injury.

Background: Oxygen-induced lung injury is believed to lead to the development of bronchopulmonary dysplasia in premature infants. We have evaluated the beneficial effects of Nigella sativa oil (NSO) on rats with hyperoxia-induced lung injury.

Methods: Thirty newborn Sprague-Dawley rats were randomly divided into 3 groups as hyperoxia (95% O(2)), hyperoxia+NSO and control (21% O(2)).

Beneficial effects of Nigella sativa oil on intestinal damage in necrotizing enterocolitis.

Aim: The aim of this study was to determine the beneficial effects of Nigella sativa oil (NSO) on rats with necrotizing enterocolitis (NEC).

Material And Methods: Thirty newborn Sprague-Dawley rats were randomly divided into three groups as NEC, NEC + NSO, and control. NEC was induced by enteral formula feeding, exposure to hypoxia-hyperoxia and cold stress.