20 results match your criteria: "G. Pini Orthopaedic Institute[Affiliation]"
J Neurosci Rural Pract
June 2023
Orthopedics and Traumatology Unit, A.S.S.T. Grande Ospedale Metropolitano Niguarda, Italy.
Objectives: During the last decades, spine surgery has grown exponentially. In spite of that, it remains a surgical specialty without a well-defined own certification. It is usually carried out, separately, by neurosurgeons and orthopedic surgeons, even if there is an overlapping of competence and skills.
View Article and Find Full Text PDFArch Plast Surg
May 2020
Department of Plastic, Reconstructive and Aesthetic Surgery, Campus Bio-Medico of Rome University, Rome.
Background: Surgical reconstruction of chronic wounds is often infeasible due to infection, comorbidities, or poor viability of local tissues. The aim of this study was to describe the authors' technique for improving the regenerative and antimicrobial potential of a combination of modified nanofat and platelet-rich plasma (PRP) in nonhealing infected wounds.
Methods: Fourteen patients met the inclusion criteria.
Plast Reconstr Surg Glob Open
June 2019
Department of Plastic, Reconstructive and Aesthetic Surgery, "Campus Bio-Medico di Roma" University, Rome, Italy.
Background: Nonsurgical rhinoplasty with hyaluronic acid (HA) has gained popularity due to its efficacy and minimal downtime. From a structural standpoint, it is like performing a tridimensional reshaping where only enhancement by grafts is allowed. To date, indications, technique, and products are still debated.
View Article and Find Full Text PDFRheumatology (Oxford)
June 2018
Rheumatology, G. Pini Orthopaedic Institute and S. Paolo Hospital, Internal Medicine I, Milan, Italy.
Clin Exp Rheumatol
March 2018
Rheumatology Unit, L. Sacco University Hospital, Milan, Italy.
Often life-threatening pulmonary fungal infections (PFIs) can occur in patients with rheumatoid arthritis (RA) receiving disease-modifying anti-rheumatic drugs (DMARDs). Most of the data concerning PFIs in RA patients come from case reports and retrospective case series. Of the ve most widely described PFIs, Pneumocystis jirovecii pneumonia (PJP) has rarely been seen outside Japan, pulmonary cryptococcosis has been diagnosed in only a small number of patients worldwide, pulmonary coccidioidomycosis has almost only been observed in endemic areas, the limited number of cases of pulmonary histoplasmosis have mainly occurred in the USA, and the rare cases of invasive pulmonary aspergillosis have only been encountered in leukopenic patients.
View Article and Find Full Text PDFBone Joint J
June 2014
IRCCS Galeazzi Orthopaedic Institute, Laboratory of Clinical Chemistry and Microbiology, Via R Galeazzi, Milan, Italy.
The treatment of chronic osteomyelitis often includes surgical debridement and filling the resultant void with antibiotic-loaded polymethylmethacrylate cement, bone grafts or bone substitutes. Recently, the use of bioactive glass to treat bone defects in infections has been reported in a limited series of patients. However, no direct comparison between this biomaterial and antibiotic-loaded bone substitute has been performed.
View Article and Find Full Text PDFCell Tissue Bank
March 2015
Musculoskeletal Tissue Bank of Milan, G. Pini Orthopaedic Institute, Milan, Italy,
The aim of this study was to analyze factors contributing to bacteriological contamination of bone and tendon allograft. Between 2008 and 2011, 2,778 bone and tendon allografts obtained from 196 organ and tissue donors or tissue donors only were retrospectively analysed. Several variables were taken into account: donor type (organ and tissue donors vs.
View Article and Find Full Text PDFKnee Surg Sports Traumatol Arthrosc
August 2012
G. Pini Orthopaedic Institute, Milan, Italy.
Congenital absence of the cruciate ligaments is a rare condition with a prevalence of 0.017 per 1,000 live births. The most important finding of this study was the presence of a posterior menisco-femoral ligament of Wrisberg with cruciate ligaments agenesia and the hypothesis advanced about the development of the ligamentous structures of the knee.
View Article and Find Full Text PDFJ Eur Acad Dermatol Venereol
May 2010
UOC DH of Rheumatology, G. Pini Orthopaedic Institute, Milan, Italy.
Background: As psoriatic disease (PD) is a condition characterized by the combination of inflammatory skin (psoriasis) and osteo-articular manifestations (psoriatic arthritis), its treatment should cover both its clinical components.
Objective: The objective of this study was to propose a flexible framework for the use of biological agents in PD.
Methods: The proposal was drawn up by a group of dermatologists and rheumatologist expert in PD and was based on existing evidence and personal opinion.
Ann N Y Acad Sci
September 2009
Day Hospital of Rheumatology, G. Pini Orthopaedic Institute, Milan, Italy.
A cohort of rheumatoid arthritis (RA) patients in the Lombardy Rheumatology Network (LOHREN) registry and receiving anti-TNF therapy was evaluated after 6, 12, 24, and 36 months. Of the 1114 patients in the registry 1064 met the clinical criteria for inclusion with 519 receiving infliximab, 303 adalimumab, and 242 etanercept. The therapeutic survival curve of these patients showed that the likelihood of continuing anti-TNF therapy was 78.
View Article and Find Full Text PDFJ Rheumatol Suppl
August 2009
U.O.C. Day Hospital of Rheumatology, G. Pini Orthopaedic Institute, 20122 Milan, Italy.
The aim of this focus is to establish the role of methotrexate (MTX) in the treatment of psoriatic disease (PD). Despite the lack of hard evidence, MTX can be regarded as the nonbiological drug of choice for the treatment of peripheral psoriatic arthritis, although its effect on psoriatic dactylitis, enthesitis, and spondylitis needs to be further studied by means of well conducted clinical trials. MTX is effective in improving the skin involvement of PD, and can be used in moderate to severe psoriasis before starting a biological agent.
View Article and Find Full Text PDFJ Rheumatol
December 2007
UOC Rheumatology Day Hospital, G. Pini Orthopaedic Institute, University of Milan, Milan, Italy.
Objective: In 1999, the Italian Society of Rheumatology started a project to determine the prevalence and clinical characteristics of aggressive rheumatoid arthritis (ARA).
Methods: For 1 year, all patients with RA for > 5 years and referred to participating centers were entered in a registry and classified as having ARA if they fulfilled the following criteria: 10 swollen joints for at least 6 weeks, positive rheumatoid factor (RF), and at least one bone erosion (if disease duration of 2 years); (a) RF-positive and having 10 swollen joints or at least one newly eroded joint, or (b) if RF-negative, having 10 swollen joints and at least one newly eroded joint (if disease duration > 2 to < 5 years).
Results: The 94 participating centers enrolled 1218 patients with RA, 1130 of whom had enough data to be classified as ARA (29.
Objective: To evaluate the feasibility and outcome of the step-down approach using either cyclosporin A (CSA) or methotrexate (MTX) as maintenance therapy following 6 months treatment with these 2 agents in combination in early, nonerosive rheumatoid arthritis (RA).
Methods: Fifty-seven patients younger than 65 years with early, nonerosive RA were first treated with CSA and MTX in combination for 6 months. They were then randomly stepped down to single-agent maintenance treatment for another 18 months.
J Rheumatol
December 1999
Rheumatology Department, G. Pini Orthopaedic Institute, Milan, Italy.
Objective: To investigate the similarities and differences in pattern and severity of clinical expression of psoriatic arthritis (PsA) in British and Italian patients.
Methods: Detailed clinical data were obtained on 48 British patients with PsA and compared with the data of 48 Italian patients. A systematic evaluation of joints, spine, and skin was performed.
J Rheumatol
August 1997
Rheumatology Unit, University of Milan, G. Pini Orthopaedic Institute, Italy.
Objective: To determine whether cyclosporin A (CyA) is a useful option in the treatment of adult onset Still's disease (ASD).
Methods: Low dose CyA was given to 6 patients with chronic or relapsing ASD who had not been prescribed any other second line agents during the previous 6 mo.
Results: The disease completely remitted in 4 patients and improved markedly in the remaining 2.
Int J Clin Pharmacol Res
January 1995
Osteoarthritis and Extra-articular Rheumatism Unit, G. Pini Orthopaedic Institute, Milan, Italy.
Chondroprotective agents represent a model for basic therapy of osteoarthritis (OA), thanks to their activity directed towards the protection and repair of articular cartilage. One of the most recent compounds capable of interfering with the pathogenic mechanisms of OA is galactosamino-glycuronoglycan-sulfate (GGGS), a highly depolymerized glycosaminoglycan with favourable chondroprotective and anti-inflammatory properties. The present paper describes the experience with GGGS given to a group of patients with symptomatic OA of the knee as compared to a parallel group treated with placebo.
View Article and Find Full Text PDFClin Exp Rheumatol
April 1989
Dept. of Rheumatology, G. Pini Orthopaedic Institute, Milan.
Cervical myelopathy is found fairly often with rheumatoid arthritis. It is one of the worst complications of the disease and can lead to tetraplegia or even to sudden death. However, when we consider the high incidence of involvement of the cervical spine in rheumatoid arthritis, the number of cases of cervical myelopathy, even of slight degree, is not very high.
View Article and Find Full Text PDFItal J Orthop Traumatol
December 1987
Orthopaedic Clinic, Centre of Sports Traumatology, G. Pini Orthopaedic Institute, Milan.
Thirty-seven fractures of the acetabulum treated surgically at the Orthopaedic Institute in Milan were reviewed 5 years after operation. The overall clinical and radiographic results over this period of time were considered to be satisfactory, but a detailed study of each case enabled us to determine some of the factors which may negatively influence the outcome of this type of fracture. These negative factors were used to devise a new classification based on whether or not there was involvement of the load bearing segment of the acetabulum and on the complexity and comminution of the fracture.
View Article and Find Full Text PDFClin Rheumatol
September 1987
Department of Rheumatology, University of Milan, G. Pini Orthopaedic Institute, Italy.
A 29-year-old white female with longstanding classical rheumatoid arthritis (RA) developed clinical and serological manifestations of systemic lupus erythematosus (SLE) with prominent signs of diffuse proliferative lupus nephritis. She fulfilled the ARA criteria for the classification of SLE as well as the ARA criteria for classical RA. The concomitant presence of these two affections in the same patient is rare and the discriminating features suggest that this coexistence may be coincidental.
View Article and Find Full Text PDFDrugs Exp Clin Res
January 1988
Department of Rheumatology, G. Pini Orthopaedic Institute, University of Milan, Italy.
Ketoprofen lysine (KL) at a dose of 160 mg b.i.d.
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