1 results match your criteria: "G. D'Annunzio University Schools of Medicine and Pharmacy[Affiliation]"
Platelet activation in obese women: role of inflammation and oxidant stress.
JAMA
November 2002
Center of Excellence on Aging, G. D'Annunzio University Schools of Medicine and Pharmacy, Chieti, Italy.
Context: Obesity, in particular abdominal adiposity, is associated with increased cardiovascular morbidity and mortality through mechanisms possibly linking the metabolic disorder to platelet and vascular abnormalities.
Objective: To investigate the clinical and biochemical determinants of lipid peroxidation and platelet activation in obese women.
Design, Setting, And Participants: Cross-sectional comparison, conducted between September 1999 and September 2001, of urinary 8-iso prostaglandin F(2alpha) (8-iso PGF(2alpha)) and 11-dehydrothromboxane B2 (11-dehyhdro-TxB2) excretion levels in 93 women: 44 with a body mass index (BMI) higher than 28 and a waist-to-hip ratio (WHR) of 0.