Alteration of thiol-disulfide homeostasis in workers occupationally exposed to arsenic.

This study evaluates the redox state in occupationally arsenic-exposed workers (n = 71) by assessing the dynamic serum thiol-disulfide homeostasis. We determined the serum thiol-disulfide homeostasis parameters of exposed workers and controls (n = 43) using a novel automated colorimetric assay. Median urinary As and 8-isoprostane levels of exposed group were significantly higher than control group (16.

Evaluating ECG and carboxyhemoglobin changes due to smoking narghile.

Purpose: This study aimed to investigate whether increased carboxyhemoglobin (COHB) levels and ECG changes, which associated with fatal ventricular dysrhythmias, including increased QT, P-wave and T peak (Tp)-Tend (Te) dispersion, can be detected after smoking narghile, which is a traditional method of smoking tobacco that is smoked from hookah device.

Materials And Methods: After local ethics committee approval, this prospective study was conducted using healthy volunteer subjects at a "narghile café," which is used by people smoking narghile in an open area. Before beginning to smoke narghile, all subjects' 12-lead electrocardiographs (ECG), measurements of COHB levels, and vital signs were recorded.

Functions of the inner ear in psoriatic arthritis.

Objective: This study aimed to investigate whether there is a negative impact as a result of psoriatic arthritis disease of the inner ear function.

Methods: Twenty-four successive patients and 38 healthy volunteers, younger than 60 years of age, who were followed up for at least for one year in the outpatient clinics of physical therapy and rehabilitation with the diagnosis of PsA according to CASPAR criteria (17) and who did not complain of any hearing impairment were included in the study. Distortion-product otoacoustic emission (DPOAE) values between 1kHz and 4kHz, tympanometric examination results, stapes reflex values, speech reception threshold (SRT) and speech discrimination (SD) values, pure-tone values between 250 and 8000Hz and high-frequency values between 10,000, 12,500 and 16,000Hz were analyzed.

The impact of topical and systemic enoxaparin sodium use on traumatic tympanic membrane perforation and myringosclerosis.

The objective of this study is to investigate the effect of topical and systemic enoxaparin sodium on the healing pattern of experimentally induced tympanic membrane perforation and formation of myringosclerosis. A total of 24 Wistar-Albino strain rats were included in the study. Standard myringotomies were performed on each rat.

Normative Spectral Domain Optical Coherence Tomography Data in Healthy Turkish Children.

Purpose: To determine the normative database of macular and retinal nerve fiber layer (RNFL) thickness parameters in healthy Turkish children by OCT.

Methods: 318 eyes of 318 children (138 boys, 183 girls) aged between 3 and 17 years were evaluated. The children were scanned by Cirrus HD-OCT (Carl Zeiss Meditec) to measure the macula, RNFL, and optic nerve head parameters.

Evaluation of ocular pulse amplitude and choroidal thickness in diabetic macular edema.

Purpose: The aim of this study is to evaluate the ocular pulse amplitude (OPA) and choroidal thickness (CT) measurements in patients with diabetic macular edema (DME) and healthy subjects.

Methods: A total of 34 patients (12 male and 22 female) who had type 2 diabetes mellitus with DME and 34 sex-matched healthy subjects (13 male and 21 female) were included in this prospective study. The intraocular pressure (IOP) and OPA were measured with Dynamic contour tonometer (Pascal DCT, Switzerland).

The Impact of Systemic and Local Administration of Ascorbic Acid on Traumatic Perforation of Tympanic Membrane and Myringosclerosis.

Objective: In the present study, tympanic membranes (TM) harvested from myringotomized rats were analyzed histopathologically to compare the systemic and local effects of ascorbic acid on the development of myringosclerosis.

Materials And Methods: Forty male Wistar-Albino rats weighing between 350-400 g were included in this study. Under otomicroscopic examination, a standard 2-mm myringotomy incision was made on the posteroinferior quadrant of the TM of both ears.

Prognostic implications of arrhythmias during primary percutaneous coronary interventions for ST-elevation myocardial infraction.

The authors reviewed current knowledge on occurrence, clinical and prognostic significance, and management of sustained ventricular arrhythmias, atrial fibrillation and bradyarrhythmias in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary interventions (PCI). Cardiac arrhythmias worsen clinical course and prognosis in patients with ST-elevation myocardial infarction undergoing primary PCI. Sustained ventricular arrhythmias developing during or early after PCI and associated with mechanical restoration of coronary flow and reperfusion do not affect mortality, whereas those related to incomplete revascularization and ongoing ischemia are associated with poor prognosis.

Increased serum dehydroepiandrosterone sulfate in the first episode but not in subsequent episodes in male patients with schizophrenia.

Background: Many studies have investigated the relationship between blood levels of dehydroepiandrosterone (DHEA) and its sulfate ester (DHEA-S), cortisol, progesterone, and testosterone and the onset, prognosis, symptom severity, and treatment response of schizophrenia. In the present study, we assessed potential differences in blood levels of neurosteroids between drug-naïve first-episode patients with schizophrenia (FES), and drug-free patients with schizophrenia who were not in the first episode but were in a phase of acute exacerbation (DFP).

Materials And Methods: The present study included 32 male FES, 28 male DFP, and 24 male healthy controls (HC).

Impact of corrective rhinologic surgery on rhinogenic headache.

Objective: In this study, the localization of the headache, mucosal contact points, sinonasal anatomic variations and the incidence of mucosal abnormalities were determined in patients with rhinogenic headache, and the efficacy of the corrective surgery on the severity of the headache and the rate of improvement on that localization were investigated.

Study Design: Conducted in a prospective manner.

Level Of Evidence: Level 2b.

Relationship between SSRIs and Metabolic Syndrome Abnormalities in Patients with Generalized Anxiety Disorder: A Prospective Study.

Objective: SSRIs are some of the most widely prescribed medications in the world. In addition to their effectiveness, SSRIs were reported to be associated with the side effects of weight gain, sexual dysfunction, drug interactions, extrapyramidal symptoms and discontinuation symptoms. However, the effects of SSRIs on metabolic parameters are poorly understood.

[Evaluation of methicillin-resistant Staphylococcus aureus bacteremia and comparison of prognosis according to vancomycin MIC values: experience of the last ten years].

Hospital acquired methicillin-resistant Staphylococcus aureus (MRSA) infections are important health problems. Mortality and morbidity rates associated with MRSA infections are increasing with mortality rates being higher for MRSA bacteremia than the other clinical presentations of MRSA infections. Initiation of treatment immediately and use of appropriate antibacterial agents may lead to better clinical outcomes in MRSA bacteremia.

Postfusion pullout strength comparison of a novel pedicle screw with classical pedicle screws on synthetic foams.

Pullout is a very common failure mode on the use of pedicle screws. Numerous studies were completed to increase the pullout strength of pedicle screws especially for osteoporotic bones. In this study, a previously designed pedicle screw type was tested before and after fusion condition.

Deep soft tissue leiomyoma of the lower extremities: a case report.

Leiomyomas, which are seldom reported as occurring in the lower extremities, arise from smooth muscle cells and are chiefly classified as cutaneous, vascular (angiomyoma), and deep soft tissue leiomyomas. Somatic and gynaecologic subtypes constitute soft tissue leiomyomas. Somatic ones uncommonly arise in the deep soft tissue of the extremities.

Deep Soft Tissue Leiomyoma of the Lower Extremities: a Case Report.

Leiomyomas, which are seldom reported as occurring in the lower extremities, arise from smooth muscle cells and are chiefly classified as cutaneous, vascular (angiomyoma), and deep soft tissue leiomyomas. Somatic and gynae-cologic subtypes constitute soft tissue leiomyomas. Somatic ones uncommonly arise in the deep soft tissue of the extremities.

Does laparoscopic cystectomy and cauterization of endometriomas greater than 3 cm diminish ovarian response to controlled ovarian hyperstimulation during IVF-ET? A case-control study.

Aims: The objective of this study is to evaluate the in vitro fertilization and embryo transfer results of patients with endometriomas pretreated with laparoscopic cystectomy and cauterization compared with age-matched tubal infertility patients.

Methods: Records of the in vitro fertilization and embryo transfer unit have been retrospectively reviewed from September 2000 to September 2004. Twenty-two patients who underwent surgery for endometriomas and participated in an in vitro fertilization and embryo transfer procedure, were detected and age-matched with 22 tubal factor infertility patients.

Neu-Laxova syndrome, grossly appearing normal on 20 weeks ultrasonographic scan, that manifested late in pregnancy: a case report.

Introduction: Neu-Laxova syndrome (NLS) is a very rare and extremely lethal syndrome almost always inherited by autosomal recessive pattern.

Case Presentation: A 21-year-old G2 P1 L0 Turkish woman was first seen at 18 weeks of gestation in antenatal policlinic. On ultrasound examination performed at 20 weeks of gestation for excluding gross abnormalities showed no abnormality and biometry of the fetus was concordant with date of gestation.