Mutation screening of crystallin genes in Chinese families with congenital cataracts.

Purpose: To identify mutations in crystallin genes in Chinese families with congenital cataracts.

Methods: Forty-two unrelated families with non-syndromic congenital cataracts were enrolled in this study. The coding exons and adjacent intronic regions of crystallin genes, including and , were analyzed with Sanger sequencing.

Novel mutations in HSF4 cause congenital cataracts in Chinese families.

Background: Congenital cataract, a kind of cataract presenting at birth or during early childhood, is a leading cause of childhood blindness. To date, more than 30 genes on different chromosomes are known to cause this disorder. This study aimed to identify the HSF4 mutations in a cohort from Chinese families affected with congenital cataracts.

[The clinical analysis of corneal interface fluid syndrome after Laser lamellar corneal refractive surgery].

To analysis, the clinical characteristics, refractive changes, and clinical treatment of interface fluid syndrome after laser lamellar corneal refractive surgery. During Dec. 2010 to Apr.