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A study of prognostic factors in 45 cases of atypical meningioma.

Acta Neurochir (Wien)

September 2016

Department of Neurosurgery, Tohoku University, Graduate School of Medicine, 1-1 Seiryo Aoba, Sendai, Japan, 980-8574.

Background: Atypical meningioma differs from Grade I meningioma in terms of high recurrence rate and short life expectancy. We evaluated the clinical course of atypical meningioma and investigated prognostic factors affecting its outcomes.

Method: We reviewed 45 patients with atypical meningioma who underwent surgical intervention between January 2000 and December 2013.

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Article Synopsis
  • A study of 534 patients with cerebral arteriovenous malformations treated using gamma knife radiosurgery (GKRS) showed high cumulative complete obliteration rates within 7 years, ranging from 92% for small volumes to 43% for larger volumes.
  • Bleeding post-GKRS occurred in 8.1% of patients, with higher risks in those who had larger niduses and previous bleeding episodes.
  • Cyst formation was observed in 4.7% of patients, with two-thirds requiring surgical intervention, indicating a need for improved GKRS techniques for more effective treatment outcomes.
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