202 results match your criteria: "Functional Outcomes per Level of Spinal Cord Injury"

ISMRM Clinical Focus Meeting 2023: "Imaging the Fire in the Brain".

J Magn Reson Imaging

August 2024

Department of Medical Imaging, Radboudumc, Nijmegen, The Netherlands.

Set during the Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM), the "Clinical Focus Meeting" (CFM) aims to bridge the gap between innovative magnetic resonance imaging (MRI) scientific research and daily patient care. This initiative is dedicated to maximizing the impact of MRI technology on healthcare outcomes for patients. At the 2023 Annual Meeting, clinicians and scientists from across the globe were invited to discuss neuroinflammation from various angles (entitled "Imaging the Fire in the Brain").

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Background/aim: Spontaneous spinal epidural hematoma (SSEH) is a rare but serious condition, accounting for less than 1% of spinal lesions, with an incidence of 0.1 per 100,000 annually. Discovered by Jackson in 1869, around 40-50% of SSEH cases often lack a definitive cause, though risk factors, such as anticoagulant usage, vascular malformations, and hypertension are recognized.

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Background: Walking ability is a crucial factor for recovery and rehabilitation of spinal cord injury (SCI) patients.

Objectives: The aim of this study was to investigate the effect of 12 weeks of rebound therapy on walking parameters in SCI patients.

Methods: Thirty members of Isfahan Spinal Cord Injury Association participated in this experimental study using a convenience sampling method.

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Epidemiology of Spinal Cord Injury in Adults in Sweden, 2016-2020: A Retrospective Registry-Based Study.

Neuroepidemiology

August 2024

Department of Clinical Neuroscience, Sahlgrenska Academy, Institute of Neuroscience and Physiology, Gothenburg University, Gothenburg, Sweden.

Article Synopsis
  • A retrospective study was conducted to analyze the epidemiological and demographic characteristics of spinal cord injury (SCI) patients in Sweden using data from a national rehabilitation quality registry.
  • The study found that the average age of onset for SCI was 56 years, with a predominantly male population (66%), and that traumatic spinal cord injuries (TSCI) were more common than non-traumatic injuries (NTSCI), particularly for tetraplegia.
  • Key findings revealed 8% of patients required breathing aids at discharge, with 58% experiencing bowel and bladder dysfunction; the median hospital stay was 40 days, longer for those with TSCI, and the incidence rates were lower than in prior studies.
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Article Synopsis
  • The study is a feasibility assessment of a virtual walking therapy for patients with spinal cord injury (SCI) experiencing chronic neuropathic pain.
  • Conducted at the Swiss Paraplegic Centre, it involved four patients who provided feedback on their satisfaction and adherence to the therapy while tracking their pain through diaries and drawings.
  • Results indicated high satisfaction and acceptance of the therapy, although only one patient showed improvement in pain levels, suggesting the need for additional research on this rehabilitation approach.
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Background: Wheelchair tennis, a globally popular sport, features a professional tour spanning 40 countries and over 160 tournaments. Despite its widespread appeal, information about the physical demands of wheelchair tennis is scattered across various studies, necessitating a comprehensive systematic review to synthesise available data.

Objective: The aim was to provide a detailed synthesis of the physical demands associated with wheelchair tennis, encompassing diverse factors such as court surfaces, performance levels, sport classes, and sexes.

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Objective: To determine whether duration of detrusor overactivity (DO) during a cystometric study is an independent predictive factor of upper urinary tract deterioration (UUTD) in patients with traumatic spinal cord injury (TSCI).

Study Design: Retrospective cohort study.

Setting: A rehabilitation facility in Chiang Mai, Thailand.

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Penile vibratory stimulation in men with spinal cord injury: an educational video demonstration.

Fertil Steril

March 2024

Desai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, Florida; The Miami Project to Cure Paralysis, University of Miami, Miller School of Medicine, Miami, Florida. Electronic address:

Objectives: To demonstrate the different techniques used to perform successful penile vibratory stimulation (PVS) to induce ejaculation in men with spinal cord injuries (SCIs).

Design: A video demonstration of the PVS procedure performed in men with SCIs using the FertiCare 2.0 medical vibrator.

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Combined Effect of Pelvic Proprioceptive Neuromuscular Facilitation with Core Strengthening on Trunk Control, Balance, and Gait in Paraplegia.

Int J Appl Basic Med Res

December 2023

Department of Physiotherapy, Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India.

Spinal cord injury (SCI) has deleterious effects on quality of life and vocation. A partial or complete loss of sensory and motor functions below the site of injury is a potential clinical sign of SCI. Trunk and pelvic control are crucial for balance and gait to perform vocational tasks of daily living.

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Study Design: Protocol for a multi-centre randomised controlled trial (the SCI-MT trial).

Objectives: To determine whether 10 weeks of intensive motor training enhances neurological recovery in people with recent spinal cord injury (SCI).

Setting: Fifteen spinal injury units in Australia, Scotland, England, Italy, Netherlands, Norway, and Belgium.

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Article Synopsis
  • Riluzole, a sodium-glutamate antagonist, is being studied for its effects on acute cervical traumatic spinal cord injuries (tSCI) following promising results in earlier trials and pre-clinical models.
  • In a global Phase III trial, patients with cervical tSCI were randomized to receive either riluzole or a placebo, focusing on changes in Upper Extremity Motor (UEM) scores over 180 days.
  • Although the trial was halted due to COVID-19, riluzole showed potential benefits for certain patient groups, with no serious drug-related side effects reported.
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Introduction: Spinal cord injury (SCI) leads to inflammation, axonal degeneration, and gliosis. A combined treatment of exercise and neural stem cells (NSC) has been proposed to improve neural repair. This study evaluated a combined treatment of high-intensity interval training (HIIT) with NSC generation from adipose-derived stem cells (ADSCs) on a contusive model of SCI in rats.

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The effects of aerobic exercise on neuroimmune responses in animals with traumatic peripheral nerve injury: a systematic review with meta-analyses.

J Neuroinflammation

May 2023

Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Amsterdam Movement Sciences-Program Musculoskeletal Health, Vrije Universiteit Amsterdam, Van Der Boechorststraat 9, 1081 BT, Amsterdam, The Netherlands.

Background: Increasing pre-clinical evidence suggests that aerobic exercise positively modulates neuroimmune responses following traumatic nerve injury. However, meta-analyses on neuroimmune outcomes are currently still lacking. This study aimed to synthesize the pre-clinical literature on the effects of aerobic exercise on neuroimmune responses following peripheral nerve injury.

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Falls During Inpatient Rehabilitation After Spinal Cord Injury: Characterization, Clock-Hour Visualization, and Time to Event Predictors.

Arch Phys Med Rehabil

August 2023

Department of Research and Innovation, Institut Guttmann, Institut Universitari de Neurorehabilitació adscrit a la UAB, Badalona, Barcelona, Spain; Universitat Autònoma de Barcelona, Bellaterra, Cerdanyola del Vallès, Spain; Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Barcelona, Spain.

Objectives: To (1) determine fall characteristics (eg, cause, location, witnesses) of inpatients with spinal cord injury (SCI) and whether they were different for ambulatory persons vs wheelchair users; (2) visualize the total number of daily falls per clock-hour for different inpatients' features (eg, cause of injury, age); (3) compare clinical and demographic characteristics of inpatients who experienced a first fall event vs inpatients who did not experience such event; and (4) identify first fall event predictors.

Design: Retrospective observational cohort study.

Setting: Institution for inpatient neurologic rehabilitation.

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Article Synopsis
  • There are differences in how different racial and ethnic groups experience stress and resources that can affect their brains, especially the amygdala, which helps process fear and trauma.
  • A study with 283 participants looked at how their brains reacted to scary and neutral faces after trauma, finding that Black and Hispanic people had different brain connections compared to White people.
  • The results suggest that these differences in brain activity and responses to stress may influence how likely someone is to develop PTSD after experiencing traumatic events.
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Objective: To evaluate the efficacy of intravesical injection of botulinum toxin type A (BTX-A) for neurogenic detrusor overactivity (DO) in reducing the frequency and severity of autonomic dysreflexia (AD).

Design: A cross-sectional nonrandomized trial with before (baseline) and after (follow-up) assessments.

Setting: A single spinal cord injury (SCI) rehabilitation center in China.

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Article Synopsis
  • The study aimed to assess the impact of underwater treadmill training (UTT) and overground walk training (OWT) on walking capacity in individuals with complete spinal cord injury (cSCI).
  • It involved five adults, averaging 41 years old, who engaged in a year-long training program focused on improving their mobility.
  • Results showed a significant increase in walking capacity as measured by the Walking Index for Spinal Cord Injury (WISCI-II), particularly highlighting improvements after completing UTT compared to initial measurements.
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Diffusion tensor imaging (DTI) literature on single-center studies contains conflicting results regarding acute effects of mild traumatic brain injury (mTBI) on white matter (WM) microstructure and the prognostic significance. This larger-scale multi-center DTI study aimed to determine how acute mTBI affects WM microstructure over time and how early WM changes affect long-term outcome. From Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI), a cohort study at 11 United States level 1 trauma centers, a total of 391 patients with acute mTBI ages 17 to 60 years were included and studied at two weeks and six months post-injury.

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Objective: Traumatic spinal cord injury (SCI) resulting in tetraplegia is a leading cause of morbidity among young adults worldwide and its management remains challenging. Restoring hand function in these patients must be considered a top priority with great impact on their quality of life (QOL); although nerve and tendon transfer have been extensively described, type of procedure to be chosen is not standardized and few studies have determined the functional outcome of those procedure and their impact on QOL is still poorly assessed. We report a preliminary retrospective study regarding feasibility and functional outcomes of nerve transfer procedures including bilateral brachialis nerve on anterior interosseous nerve (AIN) and supinator branch on posterior interosseous nerve (PIN) for hand reanimation following SCI focusing on the impact of these procedures on QOL.

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Article Synopsis
  • The INSPIRE study assessed the safety and neurological recovery of a bioresorbable polymer device called the Neuro-Spinal Scaffold (NSS) in patients with complete thoracic spinal cord injuries over a period of 24 months following implantation.
  • Out of 19 patients who received the NSS, 44% showed significant neurological improvement within 6 months, with some patients continuing to improve even after a year.
  • The findings indicate that NSS implantation is safe, with no serious adverse effects noted, and support the continued potential benefits of this treatment for spinal cord injury patients.
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Individuals with spinal cord injury (SCI) may benefit less from exercise training due to consequences of their injury, leading to lower cardiorespiratory fitness and higher risks of developing cardiovascular diseases. Arm-crank exercise (ACE) is the most common form of volitional aerobic exercise used by people with SCI outside a hospital. However, evidence regarding the specific effects of ACE alone on fitness and health in adults with SCI is currently lacking.

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Article Synopsis
  • This study aimed to compare oxygen uptake during exercise using the Adapted ROWing machine (AROW) and Arm Crank Ergometry (ACE) among individuals with spinal cord injuries or diseases (SCI/D) in Vancouver, Canada.
  • Fourteen adults with SCI/D participated in non-randomized exercise sessions, each lasting 5 minutes on both machines at chosen low and moderate workloads; key measurements included oxygen consumption and perceived exertion.
  • Results showed that the AROW led to significantly higher oxygen consumption and perceived exertion levels compared to ACE, suggesting the AROW may offer a more effective upper body workout for individuals with various levels of SCI.
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Objective: To identify goals for exercising among community-dwelling persons with spinal cord injury (PwSCI).

Design: Qualitative descriptive study.

Setting: Community-based exercise facility for persons with a disability.

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Article Synopsis
  • Arterial stiffness, indicated by cfPWV, is higher in individuals with spinal cord injury (SCI), but exercise has been shown to help reduce it in healthy individuals.
  • A clinical trial involving 46 adults with chronic, motor-complete SCI assessed the effects of two different exercise programs—body-weight-supported treadmill training (BWSTT) and arm-cycle ergometer training (ACET)—over 24 weeks.
  • Results indicated neither exercise regimen significantly affected arterial stiffness or cardiometabolic health, although peak oxygen uptake improved in participants undergoing ACET.
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