The depth of arterial supply of forehead: a meta-analysis.

Background: The rapid growth of aesthetic medicine has led to an increased demand for non-surgical cosmetic procedures in the frontal region of the face. However, alongside this rise in popularity, there is a growing awareness of the potential complications associated with these procedures especially connected with fillers. The intricate vascular anatomy of the forehead, specifically the supratrochlear (STA) and supraorbital (SOA) arteries, poses significant risks if not thoroughly understood.

Comparing COVID-19 literacy and vaccine hesitancy among health care workers, including oral health professionals, in Japan.

Background: Oral health professionals should have good COVID-19 vaccine literacy as should physicians and nurses. However, little is known about COVID-19 literacy and vaccine hesitancy among oral health professionals in Japan.

Aims: This study aimed to investigate the status of COVID-19 literacy and vaccine hesitancy among oral health professionals by comparing them with other healthcare workers (HCWs).

Ethical Use of Cadaveric Images in Anatomical Textbooks, Atlases, and Journals: A Consensus Response From Authors and Editors.

Nowadays, consent to use donor bodies for medical education and research is obtained from the body donors and their families before the donation. Recently, the International Federation of Associations of Anatomists (IFAA) published guidelines that could restrict the appearance of cadaveric images in commercial anatomical resources such as textbooks and other educational products. These guidelines state that the donor must expressly consent to using such images for this purpose.

Impact of long-term trends on outcomes in the management of colonic diverticular bleeding: mediation analyses in a large multicenter study.

Background: Despite accumulating evidence and recommendations for management of colonic diverticular bleeding (CDB), the changes in its clinical management and outcomes remain unknown.

Methods: We performed a retrospective tendency analysis on a biennial basis, a propensity score-matched cohort study between the first and latter half groups, and mediation analyses to compare the diagnostic and treatment methods between January 2010 and December 2019 (CODE BLUE-J Study).

Results: A total of 6575 patients with CDB were included.

Anatomical and histological classification of the stellate ganglion: implications for clinical nerve blocks.

Purpose: The stellate ganglion (SG), or cervicothoracic ganglion, is usually located anterior to the neck of the first rib. Various techniques, such as ultrasonographic imaging and fluoroscopic approaches, are used to assist in the anesthetic blockade of the SG. However, there are reported complications associated with SG block; some patients had medication-related or systemic side effects, and some had procedure-related or local side effects.

Fabrication of resin cements capable of disintegrating by near-infrared radiation intended for cemented prosthesis removal.

The material concept of resin cements capable of disintegrating due to near-infrared (NIR) radiation was verified. The cements were prepared by adding silicon carbide (SiC), which heats upon absorbing NIR rays, and thermally expandable particles (TEPs) to 4-META/MMA-TBB resin cement. The microtensile bond strength (µTBS) and cytocompatibility of the cements were evaluated.

Anti-integrin αvβ6 antibody as a biomarker for diagnosing ulcerative colitis: a nationwide multicenter validation study.

Background: A serum biomarker for diagnosing ulcerative colitis (UC) remains to be established. Although we recently reported an anti-integrin αvβ6 antibody (V6 Ab) for diagnosing UC with high sensitivity and specificity, no large-scale validation study exists. This study aimed to validate the diagnostic value of V6 Ab for UC using a nationwide multicenter cohort study.

Estimated potassium intake and the progression of chronic kidney disease.

Background And Hypothesis: Lower potassium intake is associated with a higher risk of chronic kidney disease (CKD) in the general population. However, there are no stated recommendations on potassium intake in the CKD population owing to limited evidence of benefits from potassium intake and concerns about the risk of hyperkalaemia. This study aimed to investigate the relationship between potassium intake and CKD progression.

Involvement of Mediterranean fever gene mutations in colchicine-responsive enterocolitis: a retrospective cohort study.

Background: The involvement of Mediterranean fever (MEFV) gene mutations in patients with inflammatory bowel disease unclassified (IBDU) remains unclear. This study aimed to determine the clinical characteristics and responsiveness to colchicine in Japanese patients with IBDU carrying MEFV mutations.

Methods: In this retrospective cohort study, we examined MEFV mutations using gene analysis, clinical information, and colchicine responsiveness.

Validation of British Society of Gastroenterology guidelines for acute lower gastrointestinal bleeding from 8,956 cases in Japan.

Background And Aims: We sought to validate the British Society of Gastroenterology (BSG) guidelines for acute lower gastrointestinal bleeding (ALGIB).

Methods: We analyzed 8,956 patients with ALGIB in CODE BLUE-J study and categorized them into four groups based on BSG guidelines. Outcomes included 30-day rebleeding, 30-day mortality, blood transfusion, therapeutic intervention, and severe bleeding.

Helpfulness of effective atomic number image in forensic dental identification: Photon-counting computed tomography is suitable.

The identities of unidentified persons are often confirmed by matching dental treatment information. Although treatment restorations consisting of artificial materials can be confirmed visually and/or by X-ray photography, they should be quantitatively analyzed. This study demonstrates that effective atomic number (Z) images can be created using photon-counting computed tomography (PC-CT) and used to identify artificial materials employed in dentistry.

Desmoplastic Fibroblastoma (Collagenous Fibroma) of the Knee: A Case Report and Literature Review.

Background/aim: Desmoplastic fibroblastoma, also known as collagenous fibroma, is a rare benign mesenchymal neoplasm that primarily arises in the subcutaneous tissue of upper extremities and limb girdles. The knee is an uncommon location for desmoplastic fibroblastoma. Recent studies have demonstrated the presence of immunoreactivity for FOS like 1 (FOSL1) and rearrangements of FOSL1.

Clinical characteristics in adolescents and young adults with polycythemia vera and essential thrombocythemia in Japan.

We report the first large-scale retrospective cohort study on adolescent and young adult (AYA) polycythemia vera (PV) and essential thrombocythemia (ET) in Japan, a subgroup analysis using Japanese multicenter registry data (JSH-MPN-R18). This study included patients with PV (n = 31) or ET (n = 141) aged 20 to 39 years at the initial visit. Hemorrhage-free survival (HFS) was better in AYA ET than in non-AYA ET (5-year HFS: 100% vs.

Ro5-4864, a translocator protein ligand, regulates T cell-mediated inflammatory responses in skin.

Translocator protein (TSPO) is a mitochondrial outer membrane protein expressed on a variety of immune cells, including macrophages, dendritic cells, and T cells, in addition to neurons and steroid-producing cells. Previous studies of TSPO ligands have suggested that TSPO is involved in multiple cellular functions, including steroidogenesis, immunomodulation, and cell proliferation. Currently, there are limited reports on the effects of TSPO or TSPO ligands on T cell-mediated immune responses.

Bioactive Self-Polymerizing Resin with Surface Pre-Reacted Glass Ionomer Fillers for Suppressed Enamel Demineralization.

The treatment of damaged enamel surfaces involves modification of the enamel surface with artificial materials or the development of a pseudo-enamel, with research focusing on bioactive and biomimetic materials. In this study, a bioactive auto-polymerizing resin (APR) was developed by adding surface-pre-reacted glass ionomer (S-PRG) fillers of different quantities to APR. Its bioactive effects were evaluated via pH neutralization, ion release, and inhibition of enamel demineralization studies.

A Non-targeted Proteomics Newborn Screening Platform for Inborn Errors of Immunity.

Purpose: Newborn screening using dried blood spot (DBS) samples for the targeted measurement of metabolites and nucleic acids has made a substantial contribution to public healthcare by facilitating the detection of neonates with genetic disorders. Here, we investigated the applicability of non-targeted quantitative proteomics analysis to newborn screening for inborn errors of immunity (IEIs).

Methods: DBS samples from 40 healthy newborns and eight healthy adults were subjected to non-targeted proteomics analysis using liquid chromatography-mass spectrometry after removal of the hydrophilic fraction.

Supervised machine learning of outbred mouse genotypes to predict hepatic immunological tolerance of individuals.

It is essential to elucidate the molecular mechanisms underlying liver transplant tolerance and rejection. In cases of mouse liver transplantation between inbred strains, immunological rejection of the allograft is reduced with spontaneous apoptosis without immunosuppressive drugs, which differs from the actual clinical result. This may be because inbred strains are genetically homogeneous and less heterogeneous than others.

Postnatal Allergic Inhalation Induces Glial Inflammation in the Olfactory Bulb and Leads to Autism-Like Traits in Mice.

Autism spectrum disorder (ASD) is one of the most prevalent neurodevelopmental disorders. To explore its pathophysiology, we investigated the association between neonatal allergic exposure and behavioral changes. Adult female C57BL/6J mice were immunized with adjuvant (aluminum hydroxide) or ovalbumin emulsified with adjuvant.

Lateral node metastasis in low rectal cancer as a hallmark to predict recurrence patterns.

Background: Lateral node metastasis confers a poor prognosis in rectal cancer. Several multidisciplinary treatments have been proposed with favorable outcomes. However, appropriate neoadjuvant/adjuvant treatments or follow-up plans based on information about the probable recurrence site have not been specified.

Predictors of encapsulated peritoneal sclerosis in patients undergoing peritoneal dialysis using neutral-pH dialysate.

Background: Encapsulated peritoneal sclerosis (EPS) is a serious complication in patients undergoing peritoneal dialysis (PD). Neutral-pH dialysate is associated with less peritoneal damage and a lower incidence of EPS than conventional PD solution. However, monitoring for peritoneal damage and predicting EPS remain important during PD therapy.