1 results match your criteria: "Fujian Medical University. The Graduate School of Fujian Medical University[Affiliation]"

Long non-coding RNA TDRG1 aggravates colorectal cancer stemness by binding with miR-873-5p to upregulate PRKAR2.

Environ Toxicol

October 2022

Department of Gastrointestinal oncology Surgery, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, P. R. China. The School of Clinical Medicine, Fujian Medical University. The Graduate School of Fujian Medical University, Xiamen, China.

The effects of long non-coding RNA TDRG1 have been established in several tumors; however, its roles in colorectal cancer (CRC) progression are never been found. Here, we found that TDRG1 level was upregulated in CRC cells compared to that in normal colon epithelial cells. Additionally, TDRG1 level was remarkably upregulated in 3D non-adherent spheres derived from the parental CRC cells.

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