1 results match your criteria: "Fudan University Shanghai 200438 China jwweng@fudan.edu.cn wnwang@fudan.edu.cn.[Affiliation]"
The importance of the compact disordered state in the fuzzy interactions between intrinsically disordered proteins.
Chem Sci
February 2022
Department of Chemistry, Multiscale Research Institute of Complex Systems and Institute of Biomedical Sciences, Fudan University Shanghai 200438 China
The intrinsically disordered C-terminal domain (CTD) of protein 4.1G is able to specifically bind a 26-residue intrinsically disordered region of NuMA, forming a dynamic fuzzy complex. As one of a few cases of extremely fuzzy interactions between two intrinsically disordered proteins/regions (IDPs/IDRs) without induced folding, the principle of the binding is unknown.
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