3,008 results match your criteria: "Frostbite"
Assessment of sous vide water baths in the acute rewarming of frostbitten extremities: A multicenter study.
Acad Emerg Med
December 2024
Department of Emergency Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Frostbite on Denali: a case series and review of treatment options.
J Wound Care
December 2024
MedStar Georgetown University Hospital, Washington, DC, US.
Article Synopsis
Cold weather injuries among the active and reserve components of the U.S. Armed Forces, July 2019-June 2024.
MSMR
November 2024
Disease Epidemiology Program, Defense Centers for Public Health-Aberdeen, Defense Health Agency, U.S. Department of Defense.
Article Synopsis
Periodic Burst Freezing in a Water-Filled Capillary Tube.
ACS Appl Mater Interfaces
December 2024
State Key Laboratory of Mechanics and Control for Aerospace Structures, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, P.R. China.
Water-filled porous structures are ubiquitous components in life sciences and engineering. At sufficiently low temperatures, the water inside the porous structures can freeze, triggering the frost heave effect and causing problems such as permafrost, frost damage, and frostbite. In this study, we report a unique pattern of frost heat release through periodic bulging and bursting at the end of a water column inside a capillary tube.
View Article and Find Full Text PDFA Preliminary Assessment of Barriers and Facilitators to Accessing Foot Care in Homeless Shelters: A Scoping Review.
Ann Vasc Surg
November 2024
Innovation Hub, Centre de Recherche du Centre Hospitalier de Montréal, Montréal, QC; Division of Vascular Surgery, Centre Hospitalier de l'Université de Montréal, Montréal, QC. Electronic address:
Article Synopsis
Codeveloped by the American Heart Association and the American Red Cross, these guidelines represent the first comprehensive update of first aid treatment recommendations since 2010. Incorporating the results of structured evidence reviews from the International Liaison Committee on Resuscitation, these guidelines cover first aid treatment for critical and common medical, traumatic, environmental, and toxicological conditions. This update emphasizes the continuous evolution of evidence evaluation and the necessity of adapting educational strategies to local needs and diverse community demographics.
View Article and Find Full Text PDFIn situ forming Hydrogel with adding ZnO Nano-particle for effectively methicillin-resistant Staphylococcus aureus infected frostbite injury.
Regen Ther
June 2024
The Third Affiliated Hospital of Anhui Medical University, Hefei's First People's Hospital, Anhui Medical University, Hefei, Anhui 230000, People's Republic of China.
Unlabelled: Hydrogel has emerged as a promising wound dressing material, and in situ forming hydrogel has emerged as a promising wound dressing recently. But most in situ forming hydrogel are normally unstable. Herein, we report an in-situ forming hydrogel synthesized from poly(Nisopropylacrylamide166---butyl acrylate9)-poly(ethyleneglycol)-poly(N-isopropylacrylamide166---butyl acrylate9) copolymer (P(NIPAM166--nBA9)-PEG-P(NIPAM166-conBA9), denoted as PEP) and zinc oxide nano-particle(ZnO nano-particle) in response to skin temperature.
View Article and Find Full Text PDFPsychosocial and personal predisposing factors of frostbite injury and associated amputation: a systematic review.
Inj Epidemiol
November 2024
School of Rehabilitation Science, University of Saskatchewan, Saskatoon, SK, Canada.
Objective: To date, systematic reviews of frostbite injuries predominantly focus on the treatment of frostbite, which narrows the scope of prevention and disregards the impact of frostbite-related predisposing factors. Comprehensively synthesizing relevant evidence to understand the psychosocial and personal predisposing factors to frostbite injury and related amputation would provide new insight into frostbite injury prevention. This review investigated the psychosocial and personal predisposing factors of frostbite injury and associated amputation.
View Article and Find Full Text PDFAccelerated Frostbite-Induced Acroosteolysis in Pediatric Insensate Hand: A Case Report and Literature Review.
J Burn Care Res
October 2024
Wayne State University School of Medicine, Detroit, MI, USA.
In pediatric patients, frostbite is a well-documented cause of epiphyseal cartilage destruction and subsequent growth deformity of the affected phalanges. Cases of full acroosteolysis, also referred to as phalangeal osteolysis, of distal phalanges as soon as three months after cold exposure have yet to be reported. We describe a complicated case of frostbite-associated phalangeal osteolysis in the dominant hand of a nine-year-old patient, in the context of post-traumatic insensate hand after sustaining prior electrical burn injuries.
View Article and Find Full Text PDFA Case of Pneumomediastinum and Pneumorrhachis in a Patient With Multiple Risk Factors.
Cureus
September 2024
Internal Medicine, Cape Fear Valley Health, Fayetteville, USA.
Pneumomediastinum is the presence of gas (usually air) in the mediastinum, which is rare and typically benign. Pneumomediastinum is classified into primary and secondary based on etiology. Its pathophysiology is due to high intra-alveolar pressures causing alveolar rupture, which releases air that travels along bronchoalveolar sheaths into the mediastinum.
View Article and Find Full Text PDFCase report: New perspectives on gait initiation strategies from a case of full toes amputation in a professional mountain climber.
Front Hum Neurosci
September 2024
Human Physiology Section of the Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy.
Article Synopsis
- A study on a 52-year-old mountain climber, who had all five toes amputated due to frostbite, investigated how his posture and movement changed under different conditions.
- Researchers performed two tasks: static posturography (measuring body sway and pressure distribution) and gait initiation (observing walking patterns), comparing performance barefoot versus with prosthetic shoes.
- Results showed that barefoot conditions led to a more cautious body position, with specific muscle patterns indicating different strategies for maintaining balance and initiating movement.
Auricular Reconstruction.
Facial Plast Surg
October 2024
Department of Otolaryngology-Head and Neck Surgery, University of Virginia, Charlottesville, Virginia.
Article Synopsis
- * The chapter outlines different strategies for auricular reconstruction based on the severity and location of injuries, including superficial, composite, and full-thickness defects.
- * It discusses specific methods for total auricular reconstruction, prosthetic options, and management strategies for traumatic injuries such as avulsions, burns, and bites.
Skin organoid transplantation promotes tissue repair with scarless in frostbite.
Protein Cell
October 2024
Stem Cell and Regenerative Medicine Lab, Institute of Clinical Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Article Synopsis
- * A study used a mouse model to examine the recovery from frostbite and employed single-cell transcriptomics to analyze cellular changes in response to the injury.
- * The application of skin organoids created from human stem cells significantly improved healing by reducing early inflammation, enhancing stem cell presence, and remodeling the extracellular matrix, offering a promising new treatment for frostbite-related injuries.
Cold Environment-Associated Extremity Lesions or Severe Hypothermia Help Differentiate Between Frostbitten and Trench Foot (Immersion Foot).
Int J Low Extrem Wounds
October 2024
Department of Plastic and Reconstructive Surgery, Aizawa Hospital, Matsumoto, Nagano, Japan.
Article Synopsis
- Cold foot injuries like frostbite and trench foot are common in very cold places.
- Frostbite is when the foot freezes, while trench foot happens when the foot gets too wet and cold, but doesn't freeze.
- It's important to tell them apart because treating them wrong can make things worse, and signs like frostbite on fingers can help doctors know which one it is.
Frostbite injuries related to recreational nitrous oxide use: incidence, management, and complications in a Swedish case series.
JPRAS Open
December 2024
Department of Reconstructive Plastic Surgery, Karolinska University Hospital, Stockholm, Sweden.
Article Synopsis
- Nitrous oxide (NO) recreational use is rising in Sweden and Europe, leading to an increase in frostbite injuries (FIs) that necessitate medical attention, particularly surgical intervention.
- A study conducted over 22 months identified 9 patients with NO-related FIs, focusing on their injuries, treatments, and outcomes; most patients had full-thickness injuries primarily caused by direct contact with gas canisters.
- The findings highlighted that surgical treatment for these injuries often results in complications, with all operated patients experiencing minor complications, and half facing major ones, underscoring the need for further research to enhance treatment strategies.
Cold exposure accelerates lysine catabolism to promote cold acclimation via remodeling hepatic histone crotonylation.
Environ Int
October 2024
Department of Occupational and Environmental Health and the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China. Electronic address:
Article Synopsis
- Cold weather can be really bad for our health, causing problems like heart attacks and frostbite, so it's important to adapt to the cold.
- Scientists wanted to find out which specific amino acids help our bodies adjust to cold temperatures.
- They discovered that lysine is super important for helping the body stay warm when it’s cold and that it helps improve how our cells work in the cold.
Biophysical evidence that frostbite is triggered on nanocrystals of biogenic magnetite in garlic cloves (Allium sativum).
Commun Biol
September 2024
Earth-Life Science Institute, Tokyo Institute of Technology, Meguro, Tokyo, Japan.
Article Synopsis
- Biologically precipitated magnetite (FeO) nanocrystals are found in various organisms, including plants, and they can act as ice nucleation particles (INPs) that initiate freezing in supercooled water.
- Research on garlic cloves showed that these magnetite INPs might trigger frost damage; when subjected to different magnetic fields, the temperature distribution of supercooling was significantly affected.
- The study found that while weak magnetic fields increased freezing chances, stronger fields decreased it, suggesting the presence of loose binding agents on the magnetite that influence ice nucleation.
Chilblain lupus erythematosus triggered by UV nail lamp exposure: A case series. .
Lupus
October 2024
Hospital Militar Central, Bogotá, Colombia.
Article Synopsis
- - Two cases of chilblain lupus erythematosus (CLE) were reported that may have been triggered by ultraviolet (UV) nail lamps.
- - The cases, alongside existing literature, indicate a potential connection between the use of UV nail lamps and the development or reactivation of CLE.
- - More research is necessary to verify this link, but healthcare providers should be cautious about the risks associated with UV nail lamps, particularly for patients with conditions sensitive to light.
Construction and validation of a risk prediction model for soldiers with frostbite in northeast China: a cross-sectional study.
BMC Public Health
September 2024
Department of Nursing, General Hospital of Northern Theater Command, Wenhua Road 83rd Shenhe Region, Shenyang, Liaoning, 110016, People's Republic of China.
Article Synopsis
- - **Study Purpose**: The research aimed to create and validate a risk prediction model for frostbite among soldiers training in extreme conditions in Northeast China, focusing on identifying risk factors for frostbite occurrence.
- - **Methodology**: In winter 2021-2022, 698 soldiers were surveyed through a questionnaire; data were split into training and testing sets, and a Logistic regression analysis was used to establish the model for predicting frostbite risk based on various factors like temperature and wind speed.
- - **Results**: Out of the training group, 19.83% suffered frostbite, primarily first-degree, with key risk factors identified. The model displayed strong predictive performance (AUC values of 0.816
3D printed multi-coupled bioinspired skin-electronic interfaces with enhanced adhesion for monitoring and treatment.
Acta Biomater
October 2024
School of Biomedical Engineering, Anhui Medical University, Hefei 230032, China. Electronic address:
Article Synopsis
- Skin-electronic interfaces are crucial for applications in diagnostics, health monitoring, and smart wearables but struggle with issues like adhesion in wet or dynamic environments.
- The researchers drew inspiration from octopus suckers and snail slime to create a hydrogel interface that enhances adhesion and durability using ultrasound techniques.
- Their newly developed patch, PAMS, is multifunctional, showing excellent sensitivity, flexibility, and biocompatibility, and successfully accelerates wound healing in experimental models.
Design, application, and recycling of zinc alginate/guar gum hydrogel-based fibers.
Int J Biol Macromol
October 2024
School of Textile and Material Engineering, Dalian Polytechnic University, Dalian 116034, China; Liaoning Engineering Technology Research Center of Function Fiber and Its Composites, Dalian Polytechnic University, Dalian 116034, China.
Article Synopsis
- Extreme cold events necessitate the creation of flexible wearable electronics for health monitoring in low temperatures.
- Researchers developed sodium zinc alginate/guar gum hydrogel fibers that are both durable and effective, resulting in a wearable sensor that works efficiently between -20 °C and -40 °C.
- To address waste from these devices, they can be recycled and converted into biomass for supercapacitors, which retain 92.53% capacitance after 10,000 cycles, promoting sustainability and resource conservation.
Keep Cool but Don't Freeze: The Influence of William J. Mills Jr. on the Treatment of Frostbite.
Wilderness Environ Med
December 2024
Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Canada.
Article Synopsis
- - Dr. William J. Mills Jr. is an Alaskan orthopedic surgeon who transformed frostbite treatment protocols, challenging a long-standing approach set by Napoleon's surgeon general in the early 1800s.
- - After recognizing the limitations of existing methods in his practice, he researched and advocated for rapid warming of frozen body parts, resulting in significant publication contributions in the 1960s that established this as the new standard treatment.
- - Mills and his team developed a simplified 2-tier classification system for frostbite (superficial and deep) that is still widely used in clinical and non-hospital settings today.
Topical frankincense treatment for frostbite based on microcirculation improvements.
J Ethnopharmacol
January 2025
Lab of Hepatopharmacology and Ethnopharmacology, School of Pharmaceutical Sciences, South-central Minzu University, No. 182, Minyuan Road, Wuhan 430074, China. Electronic address:
Article Synopsis
- Frankincense is a traditional Chinese medicine that helps improve blood flow and can be used to treat skin injuries like frostbite.
- The study looked at how frankincense oil extract (FOE) helps frostbite wounds heal faster by increasing temperature and improving skin structure.
- Results showed that FOE not only helped warm and heal the skin but also reduced inflammation and stopped cell damage, making it a promising treatment for frostbite.
Inhibition of AIM2 expression enhance treatment effect of osimertinib in treatment of glioma.
Folia Neuropathol
August 2024
Clinic of Xiangjiang Road Primary School, Tianjin, China.
Article Synopsis
- Glioma is a prevalent brain tumor accounting for 80% of cases and is challenging to treat, particularly with the limited options for effective therapy using EGFR tyrosine kinase inhibitors (TKIs) like osimertinib, which targets specific mutations.
- Osimertinib shows promise against EGFR mutations but faces complications due to the secretion of pro-cancer cytokines that may lead to treatment resistance, especially influenced by the protein AIM2.
- Research indicates that inhibiting AIM2 could enhance the therapeutic effects of EGFR-TKIs like osimertinib, potentially by regulating inflammatory gene expression and improving patient outcomes.