7 results match your criteria: "From the VA Medical Center[Affiliation]"

Objective: The aim of the study is to characterize geographic variation in electroconvulsive therapy (ECT) receipt across the United States (US) Veterans Administration (VA) healthcare system and explore potential explanatory variables.

Background: ECT is a highly effective and rapidly acting treatment for multiple mental disorders. However, there may be geographic disparities in access to ECT across the US.

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Rationale: Gq signaling in cardiac myocytes is classically considered toxic. Targeting Gq directly to test this is problematic, because cardiac myocytes have many Gq-coupled receptors.

Objective: Test whether Gq coupling is required for the cardioprotective effects of an alpha-1A-AR (adrenergic receptor) agonist.

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Joint Impact of Early Life Adversity and COMT Val158Met (rs4680) Genotypes on the Adult Cortisol Response to Psychological Stress.

Psychosom Med

April 2018

From the VA Medical Center (Lovallo, Sorocco); Department of Psychiatry and Behavioral Sciences (Lovallo, Cohoon), University of Oklahoma Health Sciences Center, Oklahoma City; Laboratory of Neurogenetics (Enoch, Hodgkinson, Goldman), National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland; Donald W. Reynolds Department of Geriatric Medicine (Sorocco), University of Oklahoma Health Sciences Center, Oklahoma City; Cognitive Science Research Center (Vincent), University of Oklahoma, Norman; Department of Psychiatry (Acheson), University of Texas Health Sciences Center at San Antonio; and Research Imaging Institute (Acheson), San Antonio, Texas.

Objective: Exposure to stress during critical periods of development can diminish stress reactivity by the hypothalamic-pituitary-adrenocortical axis. Genetic characteristics may further modify this effect of early adversity, leading to a gene by environment (G × E) interaction on stress reactivity in adulthood. Val-allele carriers of a common polymorphism of the COMT gene (Val158Met, rs4680) have rapid removal of catecholamines in the prefrontal cortex, limbic system, and reward centers.

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A New Pathway for Sympathetic Cardioprotection in Heart Failure.

Circ Res

September 2015

From the VA Medical Center, San Francisco, CA; and University of California, Department of Medicine and CVRI, San Francisco.

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Prognostic value of soluble ST2 in the Valsartan Heart Failure Trial.

Circ Heart Fail

May 2014

From the VA Medical Center, Minneapolis, MN (I.S.A., T.S.R., M.K.); University of Minnesota, Minneapolis (I.A.S., T.S.R., M.K., J.N.C.); and Critical Diagnostics, San Diego, CA (J.S.).

Background: Soluble ST2 (sST2), a biomarker related to inflammation, is associated with outcomes of patients with heart failure. In-depth analyses of the relationship among sST2, changes in sST2, and patient outcomes are reported.

Methods And Results: sST2 was measured at baseline (n=1650), 4 months (n=1345), and 12 months (n=1094) in Valsartan Heart Failure Trial.

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Misidentification of Candida parapsilosis as C famata in a clinical case of vertebral osteomyelitis.

Am J Med Sci

January 2011

From the VA Medical Center (mjb, es), Jackson, Mississippi; and Departments of Medicine (mjb, es) and Microbiology (ps, es), University of Mississippi Medical Center, Jackson, Mississippi.

A case of vertebral osteomyelitis involving misidentification of Candida parapsilosis as C famata by the VITEK 2 compact is described. Species-specific primers were used in the polymerase chain reaction to correctly identify the clinical isolate. When uncommon species of Candida are reported using automated systems, heightened clinical suspicion is warranted.

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