45 results match your criteria: "From the University of Virginia[Affiliation]"
Aggressiveness of care following intracerebral hemorrhage in women and men.
Neurology
July 2017
From the University of Virginia (R.G. and B.B.W.), Charlottesville; Columbia University (A.B.), New York, NY; University of Cincinnati (S.L.D., C.J.M., J.O., P.S., D.W.), OH; Georgetown University (J.J.L.), Washington, DC; Tufts Medical Center (X.C.), Boston, MA; Duke University (M.L.J.), Durham, NC; University of Miami (S.K., S.C.), FL; Wake Forest School of Medicine (C.D.L.), Winston-Salem, NC; Yale University School of Medicine (K.N.S.), New Haven, CT; and Banner University Medical Center Tucson (E.W.), AZ.
Objective: To compare comorbidities and use of surgery and palliative care between men and women with intracerebral hemorrhage (ICH).
Methods: The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study is a prospective, multicenter, case-control study of ICH risk factors and outcomes. We compared comorbidities, treatments, and use of do-not-resuscitate (DNR) orders in men vs women.
Community Health Workers in Collaboration With Case Managers to Improve Quality of Life for Patients with Heart Failure.
Prof Case Manag
September 2018
Patra H. Reed, DNP, RN, CNML, is Sentara Blue Ridge Regional Director for Integrated Care Management at Sentara RMH Medical Center in Harrisonburg, VA. She received her DNP and BSN degrees from James Madison University and her MSN degree from the University of Virginia. Her 23 years of nursing experience include 15 years in case management and case management leadership. Patra helped in developing the Continuum Case Management role and the community health worker program at Sentara RMH Medical Center. She has also presented these programs at local, state, and national case management conferences. Linda J. Hulton, PhD, RN, is Professor of Nursing at James Madison University and Coordinator of the Doctor of Nursing Practice program. She received her BSN degree from Roberts Wesleyan College and her master's and PhD in nursing degree from the University of Virginia, with a specialty in Community Health. Her areas of research interest are adolescent health promotion and homeless populations. Past awards include the CISAT Distinguished Teacher from James Madison University, the Alger Family Endowment Award for Community Outreach, and the Provost Award for Excellence in Graduate Advising. In 2016, she received the Virginia Nurses Foundation Leadership in Excellence in Nursing Research Award.
Quantitative Analysis of the Cellular Microenvironment of Glioblastoma to Develop Predictive Statistical Models of Overall Survival.
J Neuropathol Exp Neurol
December 2016
From the University of Virginia School of Medicine (JXY, FFB, JWM, BJH, JMM), Department of Biomedical Engineering, University (JXY, JMM), Department of Pathology (FFB, JWM), and Department of Public Health Sciences (BJH), Division of Translational Research and Applied Statistics, University of Virginia, Charlottesville, Virginia.
Glioblastomas, the most common primary malignant brain tumors, have a distinct tissue microenvironment. Although non-neoplastic cells contribute to glioblastoma progression, very few quantitative studies have shown the effect of tumor microenvironmental influences on patient survival. We examined relationships of the cellular microenvironment, including astrocytes, microglia, oligodendrocytes, and blood vessels, to survival in glioblastoma patients.
View Article and Find Full Text PDFComparison of SEER Sonorheometry With Rotational Thromboelastometry and Laboratory Parameters in Cardiac Surgery.
Anesth Analg
December 2016
From the *University of Virginia, Charlottesville, Virginia; †University of Toledo College of Medicine, Toledo, Ohio.
Background: The Quantra Hemostasis Analyzer is a novel diagnostic device that uses an ultrasound-based technology, sonic estimation of elasticity via resonance (SEER) sonorheometry, to characterize the dynamic changes in viscoelastic properties of a blood sample during coagulation. Cardiac surgery utilizing cardiopulmonary bypass (CPB) is associated with a significant impact on the coagulation system and can result in perioperative coagulopathy. The aim of this study was to correlate SEER sonorheometry results to corresponding rotational thromboelastometry (ROTEM) and laboratory parameters obtained before, during, and after CPB.
View Article and Find Full Text PDFMinimally Invasive Mitral Valve Surgery I: Patient Selection, Evaluation, and Planning.
Innovations (Phila)
May 2017
From the *University of Virginia, Charlottesville, VA USA; †Saint Elizabeth's Medical Center, Brighton, MA USA; ‡Penrose St. Francis Hospital, Colorado Springs, CO USA; §Northeast Georgia Physicians Group, Gainesville, GA USA; ∥Gulf Coast Cardiothoracic and Vascular Surgeons, Ft. Myers, FL USA; ¶Holy Spirit Northside Hospital, Chermside, Australia; #Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, MN USA; **New York University School of Medicine, New York, NY USA; ††Temple University, Philadelphia, PA USA; ‡‡Penn Presbyterian Medical Center, Philadelphia, PA USA; §§East Bay Cardiac Surgery Center, Oakland, CA USA; ∥∥Swedish Heart and Vascular Institute, Seattle, WA USA; ¶¶Northwestern University, Feinberg School of Medicine, Chicago, IL USA; ##Emory St. Joseph's Hospital, Atlanta, GA USA; ***St. Thomas Hospital, Nashville, TN USA; †††The Heart Hospital Baylor Plano, Plano, TX USA; ‡‡‡Weill Cornell Medical College/New York Presbyterian Hospital, New York, NY USA; §§§South Florida Heart & Lung Institute, Doral, FL USA; ∥∥∥David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA USA; ¶¶¶TriHealth Heart Institute, Cincinnati, OH USA; ###Central Maine Heart and Vascular Institute, Lewiston, ME USA; ****Lankenau Medical Center, Wynnewood, PA USA; and ††††Department of Cardiothoracic Surgery, Princeton Baptist Hospital, Birmingham, AL USA.
Widespread adoption of minimally invasive mitral valve repair and replacement may be fostered by practice consensus and standardization. This expert opinion, first of a 3-part series, outlines current best practices in patient evaluation and selection for minimally invasive mitral valve procedures, and discusses preoperative planning for cannulation and myocardial protection.
View Article and Find Full Text PDFA Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor.
N Engl J Med
August 2016
From the University of Virginia Health Sciences Center, Charlottesville (W.J.E., B.B.S., D.H., R.F.D.); Toronto Western Hospital (N.L., A.M.L.) and Sunnybrook Health Sciences Centre (M.S., K.H.), Toronto; Methodist Neurological Institute, Houston (W.G.O.); Stanford University School of Medicine, Stanford, CA (P.G., C.H.H., K.B.P.); Yonsei University College of Medicine, Seoul, South Korea (Y.G.K., W.L., J.W.C.); Swedish Neuroscience Institute, Seattle (R.G., J.W., S.R., R.C.); University of Maryland School of Medicine, Baltimore (H.M.E., P.S.F., D.G.); University of Miami School of Medicine, Nicklaus Children's Hospital, Miami (T.S.T.); Brigham and Women's Hospital, Boston (M.T.H., G.R.C.); and Shin-yurigaoka General Hospital, Kawasaki (T.Y.), and Tokyo Women's Medical University, Tokyo (K.A., T.T.) - both in Japan.
Background: Uncontrolled pilot studies have suggested the efficacy of focused ultrasound thalamotomy with magnetic resonance imaging (MRI) guidance for the treatment of essential tremor.
Methods: We enrolled patients with moderate-to-severe essential tremor that had not responded to at least two trials of medical therapy and randomly assigned them in a 3:1 ratio to undergo unilateral focused ultrasound thalamotomy or a sham procedure. The Clinical Rating Scale for Tremor and the Quality of Life in Essential Tremor Questionnaire were administered at baseline and at 1, 3, 6, and 12 months.
Using disease-specific, patient-reported measures in everyday clinic.
Neurology
August 2016
From the University of Virginia, Charlottesville.
Revision Anterior Cruciate Ligament Reconstruction: Results of a Single-stage Approach Using Allograft Dowel Bone Grafting for Femoral Defects.
J Am Acad Orthop Surg
August 2016
From the University of Virginia Health System, Charlottesville, VA (Dr. Werner, Dr. Gaskin, Dr. Carroll, Dr. Hart, and Dr. Miller), Presbyterian Rush Medical Center, Chicago, IL (Dr. Gilmore), and Northwest Iowa Bone, Joint, and Sports Surgeons, Spencer, IA (Dr. Hamann).
Introduction: The purpose of this study was to present results of single-stage revision anterior cruciate ligament (ACL) reconstruction using an allograft bone dowel for isolated femoral bony deficiency.
Methods: Sixteen patients underwent single-stage revision ACL reconstruction using an allograft bone dowel for isolated femoral bony deficiency between 2007 and 2012. Twelve patients (75%) completed study visits, which included CT scans as well as completion of validated outcomes measures.
Whither the "Improvement Standard"? Coverage for Severe Brain Injury after Jimmo v. Sebelius.
J Law Med Ethics
March 2016
Joseph J. Fins, M.D., M.A.C.P., is The E. William Davis, Jr. M.D. Professor of Medical Ethics and Chief of the Division of Medical Ethics at Weill Cornell Medical College where he is a Tenured Professor of Medicine, Professor of Medical Ethics in Neurology, Professor of Health Care Policy and Research, and Professor of Medicine in Psychiatry. He Co-Directs, the Consortium for the Advanced Study of Brain Injury (CASBI) at Weill Cornell and Rockefeller University, is a Senior Research Scholar in Law at the Yale Law School, an elected Member of the Institute of Medicine of the National Academy of Sciences, a Fellow of the American Academy of Arts and Sciences and an Academico de Honor (Honored Academic) of the Real Academia Nacional de Medicina de Espana (the Royal Academy of Medicine of Spain). He received his B.A. with Honors from Wesleyan University (Middletown, CT) and M.D. from Cornell University (New York, NY). Megan S. Wright, Ph.D., is a J.D. candidate (2016) at Yale Law School (New Haven, CT). She earned a Ph.D. in Sociology from the University of Arizona (Tucson, Arizona). Claudia Kraft is a third-year law student at Yale Law School (New Haven, CT). She received a B.A. in Human Biology from the University of Virginia (Charlottesville, VA). Alix Rogers, M.Phil., is concurrently pursuing a J.D. at Yale Law School (New Haven, CT), and a Ph.D. in the History and Philosophy of Science at the University of Cambridge (Cambridge, United Kingdom). She holds a M.Phil from the University of Cambridge (Cambridge, United Kingdom), and a B.A. from the University of Pennsylvania (Philadelphia, PA). Marina Romani is a J.D Candidate (2016) at Yale Law School (New Haven, CT). She received a B.S. in Biology from Dartmouth College (Hanover, NH). Samantha Godwin, J.D., is a Ph.D candidate and Gates Cambridge Scholar at Cambridge University and an LL.M student at Yale Law School. She received her B.A. and MA from University College London department of philosophy and her J.D. from
As improvements in neuroscience have enabled a better understanding of disorders of consciousness as well as methods to treat them, a hurdle that has become all too prevalent is the denial of coverage for treatment and rehabilitation services. In 2011, a settlement emerged from a Vermont District Court case, Jimmo v. Sebelius, which was brought to stop the use of an "improvement standard" that required tangible progress over an identifiable period of time for Medicare coverage of services.
View Article and Find Full Text PDF"Basal Cell Blanche": A Diagnostic Maneuver to Increase Early Detection of Basal Cell Carcinomas.
J Am Board Fam Med
November 2017
From the University of Virginia School of Medicine, Charlottesville (OLQ); the Department of Dermatology, University of Virginia Health System, Charlottesville (MB, BBW); and the Department of Dermatology, University of Mississippi, Jackson (ARC).
Basal cell carcinomas represent one of the most common skin cancers and often present initially in the primary care setting. Subtle basal cell carcinomas may be difficult to detect, and early detection of these carcinomas remains important in limiting patient morbidity. In this article, we present a simple diagnostic maneuver, "basal cell blanche," to increase early detection of basal cell carcinomas.
View Article and Find Full Text PDFGenomic Databases and Biobanks in Israel.
J Law Med Ethics
February 2017
Professor of Law at the University of Virginia School of Law and the Director of the Center for Health Law, Bioethics and Health Policy at Ono Academic College in Israel. He is a Member of the Israeli National Committee on Human Subject Research and Commissioner of the Israel National Bioethics Council. He earned his medical and law degrees from Tel Aviv University and doctorate degree in law from the University of Virginia.
Large-scale biobanks represents an important scientific and medical as well as a commercial opportunity. However, realizing these and other prospects requires social, legal, and regulatory conducive climate, as well as a capable scientific community and adequate infrastructure. Israel has been grappling with the appropriate approach to establishing such a repository, and debates over the governance, structure, finance, and mode of operation shed a bright light on the underlying social norms, civic engagement and scientific clout in steering a governmental response to pressing medical needs.
View Article and Find Full Text PDFEvolution of brain lesions in a patient with TREX1 cerebroretinal vasculopathy.
Neurology
November 2015
From the University of Virginia (R.D., D.S., M.B.S.L., B.B.W.), Charlottesville; the UCLA School of Medicine (J.C.J.), Los Angeles, CA; and the Johns Hopkins University School of Medicine (D.D.L.), Baltimore, MD.
Moral Distress: Recognition, Diagnosis, and Treatment.
J Infus Nurs
December 2016
Formerly from the University of Virginia, School of Nursing, Charlottesville, Virginia. Jennifer Trautmann, PhD, RN, FNP-BC, received her doctoral degree from the University of Virginia, Charlottesville, Virginia. She is currently a Morton K. and Jane Blaustein Post Doctoral Fellow in Mental Health and Psychiatric Nursing at Johns Hopkins University School of Nursing, Baltimore, Maryland, Jennifer has 20 years of nursing experience and 13 years of experience as a nurse practitioner. Her dissertation focused on relationships regarding advanced practice autonomy and moral distress of emergency department nurse practitioners. Her current research interest is in child mental and behavioral health and implementing parenting interventions to preschool families. Her long-term research goal is to adapt an evidence-based parenting program for military families with young children.
Infusion nursing is a unique hybrid of inpatient and ambulatory nursing. The subspecialty of nurses cares for patients requiring treatment over long periods, including cancer patients receiving chemotherapy and patients who require short bursts of treatment, such as those with multiple sclerosis, Crohn's disease, and rheumatoid arthritis. Infusion nurses are exposed to many of the common root causes of moral distress in their practice, similar to nurses caring for terminally ill or critically ill patients.
View Article and Find Full Text PDFNeurophobia: a chronic disease of medical students.
Neurology
July 2015
From the University of Virginia (G.E.S.), Charlottesville; and the University of Rochester (R.F.J.), NY.
Epithelial ovarian cancer in older women: defining the best management approach.
Am Soc Clin Oncol Educ Book
February 2016
From the University of Virginia, Charlottesville, VA; Memorial Sloan Kettering Cancer Center, New York NY; University of Oklahoma, Oklahoma City, OK.
Epithelial ovarian cancer is a cancer of older women. In fact, almost half of women diagnosed with ovarian cancer will be older than age 64, and 25% will be older than age 74. Therefore, it is crucial to examine the available data in older populations to optimize the therapeutic approach without negatively affecting the quality of life permanently.
View Article and Find Full Text PDFWhat are the concerns about custom-compounded "bioidentical" hormone therapy?
Menopause
December 2014
From the University of Virginia Midlife Health Center, Charlottesville, VA.
Unsubstantiated claims, lack of scientific safety and efficacy data, and lack of quality control surround custom-compounded bioidentical hormone products. FDA-approved hormone therapy provides tested and regulated therapy without the risks of unregulated and untested custom preparations.
View Article and Find Full Text PDFInjury tolerance of the wrist and distal forearm to impact loading onto outstretched hands.
J Trauma Acute Care Surg
September 2014
From the University of Virginia Center for Applied Biomechanics (J.F.), Charlottesville, Virginia; University of Virginia Center for Applied Biomechanics (B.P.), Charlottesville, Virginia; University of Virginia Center for Applied Biomechanics (A.A.), Charlottesville, Virginia; University of Virginia Department of Orthopaedics (A.F.) and the University of Virginia Hand Center, Charlottesville, Virginia; University of Virginia Center for Applied Biomechanics (R.S.), Charlottesville, Virginia; and Applied Research Associates (T.W.), Littleton, Colorado.
Background: The wrist/forearm complex is one of the most commonly fractured body regions, yet the impact tolerance of the wrist is poorly understood. This study sought to quantify the injury tolerance of the adult male forearm-wrist complex under loading simulating axial impact to an outstretched hand.
Methods: Fifteen isolated cadaveric forearm/wrist specimens were tested.
The Cushing response evoked by a fourth ventricular brainstem mass.
Neurology
September 2014
From the University of Virginia, Charlottesville.
We report a case of a patient with a mass lesion of the pontomedullary junction with paroxysmal episodes of autonomic and other homeostatic dysfunction that echo the classic Cushing response to intracranial hypertension.
View Article and Find Full Text PDFIn attempting to respond to current public concerns about nutrition when creating its health education program, the New American Plate, the American Institute for Cancer Research found it necessary to emphasize the importance of portion size. Justifiable concern about overweight and obesity and as yet unproved ideas about weight management were causing people to distort the shape of their diet. The focus of the new education program was reduction of cancer risk through a predominantly plant-based diet.
View Article and Find Full Text PDFA Retrospective Chart Review of Lithium Side Effects in a Geriatric Outpatient Population.
Am J Geriatr Psychiatry
January 2013
From the University of Virginia, School of Medicine.
The charts of 114 elderly outpatients with mood disorders treated with lithium were reviewed to determine the incidence of side effects. Patients had been treated with lithium for an average of 7.5 years, with an average serum lithium level of 0.
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