14 results match your criteria: "From the University of Edinburgh[Affiliation]"
Nonsurgical Management of a Caudal Mediastinal Granuloma.
J Am Anim Hosp Assoc
March 2025
From the University of Edinburgh, Edinburgh, Scotland.
A 3 yr old female springer spaniel presented with a 3-day history of pyrexia, lethargy, and a mild cough. A year prior, the dog had undergone surgical removal of a grass seed from her sublumbar muscles. Computed tomography of the thorax revealed the presence of a caudal mediastinal mass closely associated with the esophagus and diaphragm.
View Article and Find Full Text PDFAI Implementation in Thoracic Radiology: It Is Getting Closer.
Radiology
February 2025
From the University of Edinburgh Centre for Cardiovascular Science-Edinburgh Imaging, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
CT Attenuation of Periaortic Adipose Tissue in Abdominal Aortic Aneurysms.
Radiol Cardiothorac Imaging
February 2024
From the University of Edinburgh Centre for Cardiovascular Science, University of Edinburgh, 49 Little France Crescent, Chancellor's Building, Room SU.305, Edinburgh EH16 4SB, United Kingdom (S.D., E.T., M.B.J.S., J.N., A.J.F., M.R.D., D.E.N., R.O.F., M.C.W.); School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, United Kingdom (A.J.F.); Department of Medicine, Division of Artificial Intelligence, and Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, Calif (D.D.); and Edinburgh Vascular Service, Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, United Kingdom (R.O.F.).
Purpose To assess periaortic adipose tissue attenuation at CT angiography in different abdominal aortic aneurysm disease states. Materials and Methods In a retrospective observational study from January 2018 to December 2022, periaortic adipose tissue attenuation was assessed at CT angiography in patients with asymptomatic or symptomatic (including rupture) abdominal aortic aneurysms and controls without aneurysms. Adipose tissue attenuation was measured using semiautomated software in periaortic aneurysmal and nonaneurysmal segments of the abdominal aorta and in subcutaneous and visceral adipose tissue.
View Article and Find Full Text PDFBreast-Conserving Surgery with or without Irradiation in Early Breast Cancer.
N Engl J Med
February 2023
From the University of Edinburgh (I.H.K., L.J.W., D.A.C., J.M.D.) and Western General Hospital (W.J.L.J.) - both in Edinburgh.
Article Synopsis
- A phase 3 randomized trial was conducted to explore the effects of omitting radiotherapy in older women (65+) with hormone receptor-positive early breast cancer after breast-conserving surgery.
- Of the 1326 participating women, those who did not receive radiotherapy had a significantly higher local breast cancer recurrence rate (9.5%) compared to those who did (0.9%), but overall survival rates were nearly the same in both groups (around 80.8%).
- The findings suggest that while omitting radiotherapy may lead to higher local recurrences, it does not impact distant recurrence or overall survival for these patients on adjuvant endocrine therapy.
Radiologic Findings after COVID-19 and the Correlation with Lung Function.
Radiology
April 2023
From the University of Edinburgh Centre for Cardiovascular Science-Edinburgh Imaging, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, United Kingdom.
Beta-Blockers in COPD - A Controversy Resolved?
N Engl J Med
December 2019
From the University of Edinburgh Medical School, Edinburgh.
Coronary CT Angiography and 5-Year Risk of Myocardial Infarction.
N Engl J Med
September 2018
From the University of Edinburgh, Edinburgh (D.E.N., P.D.A., N.A.B., M.R.D., A.H., S.L., N.L.M., J.N., A.S.V.S., E.J.R.B., M.C.W.), the University of Glasgow, Glasgow (C.B., G.R.), the University of East Anglia, Norwich (M.F.), NHS Fife, Kirkcaldy (S.M.), and Queen Mary University, London (A.D.T.) - all in the United Kingdom; and the University of Limerick, Limerick, Ireland (J.F.).
Background: Although coronary computed tomographic angiography (CTA) improves diagnostic certainty in the assessment of patients with stable chest pain, its effect on 5-year clinical outcomes is unknown.
Methods: In an open-label, multicenter, parallel-group trial, we randomly assigned 4146 patients with stable chest pain who had been referred to a cardiology clinic for evaluation to standard care plus CTA (2073 patients) or to standard care alone (2073 patients). Investigations, treatments, and clinical outcomes were assessed over 3 to 7 years of follow-up.
Safe Surgery Globally by 2030: The View From Surgery.
Anesth Analg
April 2018
Surgical Unit, BARC Hospital (Government of India), World Health Organization Collaborating Centre for Research on Surgical Care Delivery in LMICs, Mumbai, India.
The Sequence-specific Peptide-binding Activity of the Protein Sulfide Isomerase AGR2 Directs Its Stable Binding to the Oncogenic Receptor EpCAM.
Mol Cell Proteomics
April 2018
From the ‡University of Edinburgh, Institute of Genetics and Molecular Medicine, Edinburgh, Scotland, United Kingdom, EH4 2XR;
AGR2 is an oncogenic endoplasmic reticulum (ER)-resident protein disulfide isomerase. AGR2 protein has a relatively unique property for a chaperone in that it can bind sequence-specifically to a specific peptide motif (TTIYY). A synthetic TTIYY-containing peptide column was used to affinity-purify AGR2 from crude lysates highlighting peptide selectivity in complex mixtures.
View Article and Find Full Text PDFIs Radiography Necessary for Pediatric Emergency Department Clinicians to Safely Manage Ankle Injuries?
Pediatr Emerg Care
December 2019
From the University of Edinburgh, Royal Hospital for Sick Children, Edinburgh, Scotland.
Objectives: Ankle radiography in the pediatric emergency department exposes a radiosensitive population to harmful ionizing radiation and is costly to health care systems. This study aimed to determine if ankle injuries in children could be managed safely and effectively without radiography.
Methods: This prospective study enrolled 94 patients with ankle injuries between July 14, 2015, and December 16, 2015.
Innate immune responses after resection for lung cancer via video-assisted thoracoscopic surgery and thoracotomy.
Innovations (Phila)
January 2015
From *The University of Edinburgh, Medical Research Council Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh, UK; †Department of Thoracic Surgery, The Royal Infirmary of Edinburgh, Edinburgh, UK; ‡Centre for Population Health Sciences, The University of Edinburgh, Medical School, Edinburgh, UK; §Department of Radiology, and ∥Department of Anaesthesia, The Royal Infirmary of Edinburgh, Edinburgh, UK; and ¶Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle-upon-Tyne, UK.
Objective: Innate immune responses to pulmonary resection may be critical in the pathogenesis of important postoperative pulmonary complications and potentially longer-term survival. We sought to compare innate immunity of patients undergoing major pulmonary resection for bronchogenic carcinoma via video-assisted thoracoscopic surgery (VATS) and thoracotomy.
Methods: Bronchoalveolar lavage was conducted in the contralateral lung before staging bronchoscopy and mediastinoscopy and immediately after lung resection.
Image quality with single-heartbeat 320-multidetector computed tomographic coronary angiography.
J Comput Assist Tomogr
June 2014
From the *University of Edinburgh/British Heart Foundation Centre for Cardiovascular Science, †Clinical Research Imaging Centre, University of Edinburgh; and ‡Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Objective: We aimed to establish the feasibility of single-heartbeat 320-multidetector computed tomographic coronary angiography (CTCA) and assess variables affecting image quality.
Methods: Consecutive patients (n = 249, 38% male) underwent CTCA. Two observers assessed image quality using a 4-point scale (1, excellent; 4, poor).