22 results match your criteria: "From the Stein Eye Institute[Affiliation]"
Cutaneous Lower Eyelid Retractor Release Averts Lower Lid Malposition After Inferior Rectus Muscle Recession.
Am J Ophthalmol
January 2025
From the Stein Eye Institute and Department of Ophthalmology, University of California (W.-Y.L., J.L.D.), Los Angeles, California, USA; Department of Neurology, University of California (J.L.D.), Los Angeles, California, USA; Bioengineering Department, University of California (J.L.D.), Los Angeles, California, USA; Neuroscience Interdepartmental Program, University of California (J.L.D.), Los Angeles, California, USA. Electronic address:
Article Synopsis
- - The study investigates the impact of cutaneous lower eyelid retractor release (CLERR) during inferior rectus (IR) muscle recession, finding that CLERR significantly reduces lower eyelid retraction and corneal exposure symptoms after the procedure.
- - A total of 89 IR recessions were reviewed, showing that those involving CLERR resulted in a greater recession (4.6 mm) and less scleral show (0.2 mm) compared to surgeries without CLERR (3.2 mm and 0.7 mm, respectively).
- - CLERR is noted as a quick and effective technique that minimizes lower eyelid retraction, making it a valuable method for strabismus surgeons, with minimal complications and quick
A New Era of Ophthalmology Leadership? A Descriptive and Comparative Analysis of Ophthalmology Department Chairs in 2024.
Am J Ophthalmol
January 2025
From the Stein Eye Institute (S.A.C., V.L.T., A.L.C.), University of California Los Angeles, Los Angeles, California, USA. Electronic address:
Purpose: To (1) characterize and analyze the demographics and scholarly achievements of United States (US) academic ophthalmology department chairs, and (2) to elucidate trends in the academic and demographic profiles of newly hired department chairs.
Design: Cross-sectional study.
Methods: Online search of publicly available resources conducted January 1, 2024.
Multifocal Vitelliform Paravascular Retinopathy (MVPR): A New Disorder in the Vitelliform Spectrum.
Am J Ophthalmol
January 2025
From the Stein Eye Institute (W.S., D.S.), University of California, Los Angeles, California, USA; Greater Los Angeles VA Healthcare Center (D.S.), Los Angeles, California, USA. Electronic address:
Purpose: To describe a new retinal phenotype characterized by bilateral, multifocal, subretinal vitelliform lesions along the vascular arcades that we refer to as multifocal vitelliform paravascular retinopathy (MVPR).
Design: Observational case series.
Methods: Multimodal retinal imaging including color fundus photography, fundus autofluorescence and cross sectional and en-face optical coherence tomography was performed to evaluate and characterize the lesions of MVPR.
Laterality Targeting in Graded Inferior Rectus Tenotomy Corrects Lateral Incomitance of Hypertropia in Sagging Eye Syndrome.
Am J Ophthalmol
January 2025
From the Stein Eye Institute and Department of Ophthalmology University of California (W.Y.L., J.L.D.), Los Angeles, California, USA; Department of Neurology (J.L.D.), University of California, Los Angeles, California, USA; Bioengineering Department (J.L.D.), University of California, Los Angeles, California, USA. Electronic address:
Purpose: To determine if laterally selective graded vertical rectus tenotomy (GVRT) of the inferior rectus (IR) can correct the lateral incomitance of hypertropia (HT) commonly encountered in sagging eye syndrome (SES), comparing it with inferior oblique (IO) recession.
Design: Retrospective comparative interventional clinical study.
Methods: We reviewed 73 consecutive patients undergoing GVRT of the IR for correction of horizontally incomitant HT due to SES from July 2012 to October 2023.
Co-existence of Neurotrophic Keratopathy in Eyes With Limbal Stem Cell Deficiency.
Am J Ophthalmol
November 2024
From the Stein Eye Institute (D.N., C.B., S.S.M.F., R.U., S.X.D.), David Geffen School of Medicine at UCLA, Los Angeles, California, USA; Molecular Biology Institute (S.X.D.), University of California, Los Angeles, California, USA. Electronic address:
Purpose: To investigate whether neurotrophic keratopathy is present in limbal stem cell deficiency (LSCD), by measuring corneal sensation and characterizing corneal subbasal nerve plexus.
Design: Prospective, cross-sectional, case-control comparative study.
Methods: A total of 46 eyes with LSCD and 14 normal eyes were recruited from 2019 to 2022.
Biomechanics Explains Variability of Response of Small Hypertropia to Graded Vertical Rectus Tenotomy.
Am J Ophthalmol
September 2024
From the Stein Eye Institute and Department of Ophthalmology, University of California, Los Angeles (C.K., S.L., J.L.D.), Los Angeles, California, USA; Department of Neurology, University of California, Los Angeles (J.L.D.), Los Angeles, California, USA; Bioengineering Department, University of California, Los Angeles (J.L.D.), Los Angeles, California, USA. Electronic address:
Purpose: Small angle hypertropia in sagging eye syndrome is conveniently treated by graded vertical rectus tenotomy, yet an adjustable technique under topical anesthesia has been recommended because of variability of effect. We performed graded tenotomy in an experimental model to elucidate the reason for variability of response to this surgical procedure.
Design: Experimental study.
Biometry challenges in the longest eyes we have encountered to date.
Am J Ophthalmol Case Rep
March 2024
From the Stein Eye Institute and Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Purpose: This report aims to present biometry challenges and solutions for a patient with the longest eyes we have encountered to date.
Observations: A 41-year-old woman with a history of Crouzon syndrome, extreme axial myopia, and posterior segment staphylomas was referred for cataract evaluation. Optical biometry was attempted using two partial coherence interferometry and optical low-coherence reflectometry devices that were available in 2011.
Magnetic Resonance Imaging of Globe Translation in Abducens Palsy.
Am J Ophthalmol
February 2024
From the Stein Eye Institute and Department of Ophthalmology (C.K., J.L.D), University of California, Los Angeles, California, USA; Department of Neurology (J.L.D.), University of California, Los Angeles, California, USA; Bioengineering Department (J.L.D.), University of California, Los Angeles, California, USA. Electronic address:
Purpose: It has been supposed that rectus muscle paralysis would cause proptosis due to the reduction in active posterior tension. This study aimed to test this proposition by evaluating globe translation during horizontal duction in patients with abducens palsy.
Design: Prospective, single-center, fellow-eye controlled, case series.
Experimental study of occlusion break surge volume in 3 different phacoemulsification systems.
J Cataract Refract Surg
November 2021
From the Stein Eye Institute and Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California (Miller); Alcon Research LLC, Lake Forest, California (Dyk, Yalamanchili).
Purpose: To evaluate surge volume after occlusion breaks in 3 different phacoemulsification systems.
Setting: Alcon Research LLC, Lake Forest, California.
Design: Experimental study.
Comparison of early visual outcomes after low-energy SMILE, high-energy SMILE, and LASIK for myopia and myopic astigmatism in the United States.
J Cataract Refract Surg
January 2021
From the Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles (Chen, Khorrami, Nejad), Los Angeles, and Hamilton Eye Institute (Hamilton, Nutkiewicz), Los Angeles, California, USA.
Purpose: To compare uncorrected distance visual acuities (UDVAs) and induced higher-order aberrations (HOAs) in the early postoperative period between low-energy (LE) small-incision lenticule extraction (SMILE), high-energy (HE) SMILE, and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) procedures.
Setting: University based refractive surgery center.
Study Design: Retrospective cohort study.
Orbital Volume Increases With Age: A Computed Tomography-Based Volumetric Study.
Ann Plast Surg
December 2019
Department of Plastic Surgery, University of California, Irvine, Newport Beach, CA.
Objective: The aim of the study was to determine whether the bony orbital volume (BOV) changes with age in males and females.
Methods: This case-control study reviewed high-resolution (<1-mm slices) computed tomography (CT) scans of consecutive patients seen for 4 years. The scans were requested as part of the patient's routine care for symptoms related to sinus symptoms.
Phacoemulsifier occlusion break surge volume reduction.
J Cataract Refract Surg
December 2018
From the Stein Eye Institute and Department of Ophthalmology (Thorne, Miller), David Geffen School of Medicine at University of California Los Angeles, Los Angeles, and Alcon Research Ltd. (Dyk, Fanney), Lake Forest, California, USA. Electronic address:
Purpose: To compare the volumetric occlusion break surge responses of phacoemulsification units from 1 company over 3 generations under varying vacuum limits and target intraocular pressure (IOP) settings.
Setting: Alcon Research, Ltd., Lake Forest, California, USA.
Safety and efficacy of black iris diaphragm intraocular lens implantation in eyes with large iris defects: Report 4.
J Cataract Refract Surg
June 2018
From the Stein Eye Institute and the Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Purpose: To assess the safety and efficacy of Morcher 67B black iris diaphragm intraocular lens (IOL) implantation for managing large iris defects and aphakia.
Setting: Stein Eye Institute, UCLA, Los Angeles, California, USA.
Design: Prospective case series.
Medical and surgical management of the small pupil during cataract surgery.
J Cataract Refract Surg
August 2018
From the Stein Eye Institute and Department of Ophthalmology (Al-Hashimi, Hamilton), David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, the Bascom Palmer Eye Institute (Donaldson), Miller School of Medicine, Plantation, Florida, the University of Colorado Eye Center (Davidson), University of Colorado School of Medicine, Denver, Colorado, the UPMC Eye Center (Dhaliwal), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, Jacksoneye (Jackson), Lake Villa, Illinois, Lexington Eye Associates (Kieval), Lexington, Massachusetts, Eye Centers of Tennessee (Patterson), Crossville, Tennessee, and the Department of Ophthalmology (Stonecipher), University of North Carolina, Chapel Hill, North Carolina, USA.
As cataract surgery continues to evolve, the intraoperative small pupil continues to pose challenges to even the most experienced cataract surgeon. Several steps can be taken preoperatively to decrease the chance of intraoperative miosis. Even so, the problem of miosis during cataract surgery remains a relatively common occurrence.
View Article and Find Full Text PDFAqueous volume loss associated with occlusion break surge in phacoemulsifiers from 4 different manufacturers.
J Cataract Refract Surg
July 2018
From the Stein Eye Institute and Department of Ophthalmology (Aravena, Thorne, Miller), David Geffen School of Medicine, University of California Los Angeles, Los Angeles and Alcon Research Ltd. (Dyk, Fanney), Lake Forest, California, USA Dr. Aravena is now with the Departamento de Oftalmología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Electronic address:
Purpose: To evaluate aqueous volume losses associated with occlusion breaks at varying vacuum limits in phacoemulsification systems from 4 different manufacturers.
Setting: Alcon Research Ltd., Lake Forest, California, USA.
Outcomes of cataract surgery in eyes with ocular melanoma treated with iodine-125 brachytherapy.
J Cataract Refract Surg
March 2018
From the Stein Eye Institute and Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA. Electronic address:
Purpose: To evaluate visual and surgical outcomes of cataract surgery in eyes with a history of iodine-125 (I) brachytherapy for ocular melanoma.
Setting: Department of Ophthalmology, David Geffen School of Medicine at UCLA and the Stein Eye Institute, Los Angeles, California, USA.
Design: Retrospective case series.
Structural and functional insights into the interaction between the Cas family scaffolding protein p130Cas and the focal adhesion-associated protein paxillin.
J Biol Chem
November 2017
From the Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095,
The Cas family scaffolding protein p130Cas is a Src substrate localized in focal adhesions (FAs) and functions in integrin signaling to promote cell motility, invasion, proliferation, and survival. p130Cas targeting to FAs is essential for its tyrosine phosphorylation and downstream signaling. Although the N-terminal SH3 domain is important for p130Cas localization, it has also been reported that the C-terminal region is involved in p130Cas FA targeting.
View Article and Find Full Text PDFComparison of a new optical biometer using swept-source optical coherence tomography and a biometer using optical low-coherence reflectometry.
J Cataract Refract Surg
August 2016
From the Stein Eye Institute, University of California, Los Angeles, and St. Mary's Eye Center (Hoffer), Santa Monica, California, USA; the Augen und Laserklinik (Hoffmann), Castrop-Rouxelle, Germany; the G.B. Bietti Foundation IRCCS (Savini), Rome, Italy.
Purpose: To investigate agreement between the IOLMaster 700 based on swept-source optical coherence tomography (SS-OCT) and the Lenstar LS 900 based on optical low-coherence reflectometry (OLCR).
Setting: Private practice, Castrop-Rouxelle, Germany.
Design: Prospective evaluation of diagnostic test.
Outcomes of implantation of modified capsule tension rings with multiple black occluder paddles for eyes with congenital and acquired iris defects: Report 3.
J Cataract Refract Surg
June 2016
From the Stein Eye Institute and the Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Purpose: To evaluate the safety and efficacy of Morcher 50F iris diaphragm implantation to manage moderate to large defects of the human iris.
Setting: Stein Eye Institute, UCLA, Los Angeles, California, USA.
Design: Prospective nonrandomized interventional case series.
Development of a nomogram for femtosecond laser astigmatic keratotomy for astigmatism after keratoplasty.
J Cataract Refract Surg
April 2016
From the Stein Eye Institute (St. Clair, Sharma, Yu, Jun, Aldave), David Geffen School of Medicine, University of California, Los Angeles, California, the Casey Eye Institute (Huang), Oregon Health Sciences University, Portland, Oregon, and the Bascom Palmer Eye Institute (Yoo, Cabot), University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA; the Department of Ophthalmology and Vision Sciences (Goldich, Rootman), the University of Toronto, Canada; the Refractive Center (Zhang), the Third Hospital of Dailan, Dailan, China. Electronic address:
Purpose: To develop a nomogram for femtosecond laser astigmatic keratotomy (AK) to treat post-keratoplasty astigmatism.
Setting: Three academic medical centers.
Design: Retrospective interventional case series.
Anterior chamber depth studies.
J Cataract Refract Surg
September 2015
From the Stein Eye Institute (Hoffer), University of California, Los Angeles, and St. Mary's Eye Center (Hoffer), Santa Monica, California, USA; the G.B. Bietti Foundation-IRCCS (Savini), Rome, Italy.
Purpose: To compare the anterior chamber depth (ACD; corneal epithelium to lens) using 3 modalities and compare the change 1 day and 3 months postoperatively.
Setting: Private practice, Santa Monica, California, USA.
Design: Nonrandomized prospective series.
Bisretinoid-mediated complement activation on retinal pigment epithelial cells is dependent on complement factor H haplotype.
J Biol Chem
March 2014
From the Stein Eye Institute, Department of Ophthalmology.
Age-related macular degeneration (AMD) is a common central blinding disease of the elderly. Homozygosity for a sequence variant causing Y402H and I62V substitutions in the gene for complement factor H (CFH) is strongly associated with risk of AMD. CFH, secreted by many cell types, including those of the retinal pigment epithelium (RPE), is a regulatory protein that inhibits complement activation.
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