1 results match your criteria: "From the St. John's University[Affiliation]"
Cardiotoxic (Arrhythmogenic) Effects of 1,1-Difluoroethane Due to Electrolyte Imbalance and Cardiomyocyte Damage.
Am J Forensic Med Pathol
June 2017
From the St. John's University, Queens, NY.
Article Synopsis
- Inhalant abuse involves inhaling chemical vapors, such as 1,1-difluoroethane (DFE), to achieve euphoric effects, often leading to serious health risks.
- An animal study was conducted with Sprague Dawley rats to explore the effects of DFE inhalation on electrolyte levels, cardiomyocyte damage, and oxidative stress, simulating human inhalant abuse scenarios.
- The results indicated that DFE can cause significant increases in plasma potassium and magnesium levels, elevated cardiac enzymes, and hyperemia in heart tissues, suggesting it leads to fatal cardiac arrhythmias and underlining the need for awareness in clinical settings related to inhalant abuse.