2 results match your criteria: "From the Institute for Environmental Medicine[Affiliation]"
Mutation of Serine 32 to Threonine in Peroxiredoxin 6 Preserves Its Structure and Enzymatic Function but Abolishes Its Trafficking to Lamellar Bodies.
J Biol Chem
April 2016
From the Institute for Environmental Medicine, Department of Physiology, and
Peroxiredoxin 6 (Prdx6), a bifunctional protein with phospholipase A2 (aiPLA2) and GSH peroxidase activities, protects lungs from oxidative stress and participates in lung surfactant phospholipid turnover. Prdx6 has been localized to both cytosol and lamellar bodies (LB) in lung epithelium, and its organellar targeting sequence has been identified. We propose that Prdx6 LB targeting facilitates its role in the metabolism of lung surfactant phosphatidylcholine (PC).
View Article and Find Full Text PDFHyperbaric oxygen: its mechanisms and efficacy.
Plast Reconstr Surg
January 2011
Philadelphia, Pa. From the Institute for Environmental Medicine and Department of Emergency Medicine, University of Pennsylvania Medical Center.
Background: This article outlines therapeutic mechanisms of hyperbaric oxygen therapy and reviews data on its efficacy for clinical problems seen by plastic and reconstructive surgeons.
Methods: The information in this review was obtained from the peer-reviewed medical literature.
Results: Principal mechanisms of hyperbaric oxygen are based on intracellular generation of reactive species of oxygen and nitrogen.