100 results match your criteria: "From the *Centers for Disease Control and Prevention[Affiliation]"

Zika Virus Shedding in Semen of Symptomatic Infected Men.

N Engl J Med

April 2018

From the Centers for Disease Control and Prevention (CDC) National Center for Emerging and Zoonotic Infectious Diseases, Fort Collins, CO (P.S.M., N.K.D., S.A.H., M.D., M.F., H.B., R.J.M., M.A., A.M.S., W.-P.T., C.A.N., E.M.M., A.C.B., A.F.H.); and the CDC National Center for Chronic Disease Prevention and Health Promotion (D.O.M.) and the CDC National Center for HIV-AIDS, Viral Hepatitis, STD, and TB Prevention (J.T.B.) - both in Atlanta.

Background: Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that has been linked to adverse birth outcomes. Previous reports have shown that person-to-person transmission can occur by means of sexual contact.

Methods: We conducted a prospective study involving men with symptomatic ZIKV infection to determine the frequency and duration of ZIKV shedding in semen and urine and to identify risk factors for prolonged shedding in these fluids.

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Standardized Hypertension Management to Reduce Cardiovascular Disease Morbidity and Mortality Worldwide.

South Med J

March 2018

From the Centers for Disease Control and Prevention, Atlanta, Georgia, the Pan American Health Organization, Washington, DC, the University of the West Indies, Cave Hill Campus, St Michael, Barbados, the Medical University of South Carolina, Charleston, and the University of South Carolina School of Medicine, Columbia.

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Shiga Toxin-Producing E. coli Infections Associated with Flour.

N Engl J Med

November 2017

From the Centers for Disease Control and Prevention (S.J.C., L.B., L.W., A.B., M.N.S., D.W., E.T., M.E.W., K.P.N.), and IHRC (L.B., D.W.), Atlanta; Food and Drug Administration, College Park, MD (L.N.S., B.M.W., J.B., S.V.); Colorado Department of Public Health and Environment, Denver (N.C.); Washington State Department of Health, Shoreline (B.M.), and Food and Drug Administration, Bothell (J.W., L.A.N.) - both in Washington; Michigan Department of Health and Human Services, Lansing (K.D.A., D.D.); Oklahoma State Department of Health, Oklahoma City (J.S.); and Virginia Department of Health, Richmond (K.A., J.R.).

Article Synopsis
  • - In 2016, an outbreak of Shiga toxin-producing Escherichia coli (STEC) infections linked to contaminated flour led to an investigation that identified 56 cases across 24 states.
  • - The study showed a significant association between the outbreak and a specific brand of flour, as well as the consumption of unbaked dough, with high odds ratios indicating a strong link.
  • - Laboratory tests confirmed the presence of outbreak strains in flour samples, and whole-genome sequencing connected the clinical and food samples to a single flour production facility, highlighting the risk of raw flour as a source of foodborne illness.
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Effectiveness of a Third Dose of MMR Vaccine for Mumps Outbreak Control.

N Engl J Med

September 2017

From the Centers for Disease Control and Prevention, Atlanta (C.V.C., K.W., H.E.G., M.S., M.M., D.R.F., M.P.); Maximus Federal, Falls Church, VA (R.M.D.); and the University of Iowa (L.J.) and Johnson County Public Health (J.R.), Iowa City, and the Iowa Department of Public Health, Des Moines (P.Q.).

Background: The effect of a third dose of the measles-mumps-rubella (MMR) vaccine in stemming a mumps outbreak is unknown. During an outbreak among vaccinated students at the University of Iowa, health officials implemented a widespread MMR vaccine campaign. We evaluated the effectiveness of a third dose for outbreak control and assessed for waning immunity.

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US Public Sexually Transmitted Disease Clinical Services in an Era of Declining Public Health Funding: 2013-14.

Sex Transm Dis

August 2017

From the *Centers for Disease Control and Prevention, Atlanta, GA; †National Association of County and City Health Officials; and ‡National Coalition of STD Directors, Washington DC.

Background: We examined the infrastructure for US public sexually transmitted disease (STD) clinical services.

Methods: In 2013 to 2014, we surveyed 331 of 1225 local health departments (LHDs) who either reported providing STD testing/treatment in the 2010 National Profile of Local Health Departments survey or were the 50 local areas with the highest STD cases or rates. The sample was stratified by jurisdiction population size.

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Background: From 2012 to 2014, rates of congenital syphilis increased in Louisiana and Florida. We evaluated the effectiveness of early (first or second) and third trimester syphilis screening for the prevention of congenital syphilis in these high-morbidity states.

Methods: Reported syphilis cases among pregnant women in Louisiana and Florida during January 1, 2013, to December 31, 2014, were reviewed for documented screening for syphilis in the first 2 trimesters and third trimester.

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Reflective Responses Following a Role-play Simulation of Nurse Bullying.

Nurs Educ Perspect

July 2018

About the Authors Deborah L. Ulrich, PhD, RN, ANEF, is interim dean, Wright State University College of Nursing and Health, Dayton, Ohio. Gordon Lee Gillespie, PhD, DNP, FAEN, FAAN, is deputy director, Occupational Health Nursing Program, University of Cincinnati College of Nursing, Cincinnati, Ohio. Maura C. Boesch, DNP, MPH, RN, is a faculty member, Wright State University College of Nursing and Health. Kyle M. Bateman, BSN, RN, CCRN, is a staff nurse, Union Memorial Hospital, Baltimore, Maryland. Paula L. Grubb, PhD, is a research psychologist, CDC-National Institute for Occupational Safety and Health, Cincinnati, Ohio. This research study was funded by Contract No. 200-2013-M-57090 from the Centers for Disease Control and Prevention-National Institute for Occupational Safety and Health (CDC-NIOSH). Its contents are solely the responsibility of the authors and do not necessarily represent the official view of the CDC-NIOSH. For more information, contact Dr. Ulrich at

A qualitative exploratory design was used for this study to evaluate role-play simulation as an active learning strategy. The context for the role-play was bullying in nursing practice. Following a simulation, 333 students from five college campuses of three universities completed a reflection worksheet.

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Long-Acting Reversible Contraception.

N Engl J Med

February 2017

From the Centers for Disease Control and Prevention, Atlanta (K.M.C.); and the Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis (J.F.P.).

A 17-year-old high school student who has never been pregnant presents for advice regarding contraception. She has an unremarkable medical history and is planning to become sexually active with her boyfriend in the near future. Her primary concern is an unintended pregnancy, and she inquires about methods of contraception that are highly effective.

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Perinatal Antiretroviral Exposure and Prevented Mother-to-child HIV Infections in the Era of Antiretroviral Prophylaxis in the United States, 1994-2010.

Pediatr Infect Dis J

January 2017

From the *Centers for Disease Control and Prevention (CDC), Washington, DC; National Center for Viral Hepatitis, HIV/AIDS, Sexually-Transmitted Disease and Tuberculosis Prevention (NCHHSTP), Division of HIV/AIDS Prevention (DHAP), Epidemiology Branch, Atlanta, GA; and †CDC, NCHHSTP, DHAP, Quantitative Sciences and Data Management Branch, Atlanta, GA.

Article Synopsis
  • The study analyzed the number of HIV-exposed and infected infants born in the U.S. from 1978 to 2010, assessing the impact of interventions aimed at preventing mother-to-child transmission (PMTCT).
  • It found about 186,157 HIV-exposed and 21,003 HIV-infected infants were born during this period, with a significant number showing prenatal exposure to antiretroviral (ARV) drugs.
  • Between 1994 and 2010, PMTCT efforts helped prevent approximately 21,956 cases of mother-to-child HIV transmission, demonstrating the effectiveness of these interventions.
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Before any vaccine introduction, overall DNA prevalence of any 9-valent human papillomavirus (9vHPV) types, HPV 31/33/45/52/58, and HPV 16/18 was 16.0%, 9.5%, and 6.

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Molecular Typing of Treponema pallidum in Ocular Syphilis.

Sex Transm Dis

August 2016

From the *Centers for Disease Control and Prevention, Atlanta, GA; †Department of Neurology, and ‡Department of Medicine (Infectious Diseases), University of Washington School of Medicine, Seattle, WA.

Background: Syphilis can have many clinical manifestations, including eye involvement, or "ocular syphilis." In 2015, an increase in reported cases of ocular syphilis and potential case clusters raised concern for an oculotropic strain of Treponema pallidum, the infectious agent of syphilis. Molecular typing was used to examine strains found in cases of ocular syphilis in the United States.

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Targeted Estimation of Marginal Absolute and Relative Associations in Case-Control Data: An Application in Social Epidemiology.

Epidemiology

July 2016

From the aSequoia Foundation, La Jolla, CA; bDivision of Biostatistics, and cDivision of Epidemiology, School of Public Health, University of California, Berkeley, CA.The study was funded in part by the University of California, Berkeley, Committee on Research and Contract # 200-2007-M-23716 from the Centers for Disease Control and Prevention.

Background: Case-control studies are useful for rare outcomes, but typical analyses limit investigators to parametric estimation of conditional odds ratios. Several methods exist for obtaining marginal risk differences and risk ratios in a case-control setting, including a recently described semiparametric targeted approach optimized for rare outcomes.

Methods: Using case-control data from a study of neighborhood poverty and very preterm birth, we demonstrate estimation of marginal risk differences and risk ratios and compare a parametric substitution estimator based on maximum likelihood estimation with targeted maximum likelihood estimation (TMLE), and a refinement of TMLE for rare outcomes that incorporates bounds on the conditional risk.

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Public Health 3.0: Time for an Upgrade.

Am J Public Health

April 2016

Karen B. DeSalvo is Acting Assistant Secretary for Health with the US Department of Health and Human Services (HHS), Washington, DC. Patrick W. O'Carroll is Acting Deputy Assistant Secretary for Health (Science and Medicine) with the Office of the Assistant Secretary for Health, HHS. Denise Koo is Advisor to the Acting Assistant Secretary for Health, HHS, on detail from the Centers for Disease Control and Prevention (CDC). John M. Auerbach is Associate Director for Policy with CDC, Atlanta, GA. Judith A. Monroe, MD, is Director, Office for State, Tribal, Local and Territorial Support with CDC.

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Clinical Management of Ebola Virus Disease in the United States and Europe.

N Engl J Med

February 2016

From the Centers for Disease Control and Prevention (T.M.U., J.G.) and the Division of Infectious Diseases, Emory University School of Medicine (A.K.M.) - both in Atlanta; the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (R.T.D.); Texas Health Presbyterian Hospital Dallas, Dallas (A.M.L.); the Department of Infectious Diseases, University Hospital Frankfurt, Frankfurt am Main (T.W.), the First Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg (S.S.), and Leipzig Treatment Center for Highly Contagious Diseases, Klinikum St. Georg, Leipzig (T.G.) - all in Germany; the Division of Infectious Diseases and Laboratory of Virology, Geneva University Hospitals, Geneva (P.V.); the Department of Infection, Royal Free London NHS Foundation Trust, London (M.J.); the Internal Medicine Department, Infectious Diseases Unit Madrid, Hospital La Paz-Carlos III IdiPAZ, Madrid (J.R.A.); New York University School of Medicine-Bellevue Hospital Center, New York (L.E.); University of Nebraska Medical Center, Omaha (A.L.H.); the Departments of Infectious Diseases and Acute Medicine, Oslo University Hospital, Oslo (A.B.B.); Lazzaro Spallanzani National Institute for Infectious Diseases, Rome (G.I.); the Infectious and Tropical Diseases Department, Bégin Military Hospital, Saint-Mandé, France (C.R.); and the Department of Internal Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht, the Netherlands (A.I.M.H.).

Background: Available data on the characteristics of patients with Ebola virus disease (EVD) and clinical management of EVD in settings outside West Africa, as well as the complications observed in those patients, are limited.

Methods: We reviewed available clinical, laboratory, and virologic data from all patients with laboratory-confirmed Ebola virus infection who received care in U.S.

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Background: Verifying correct treatment of reported cases of gonorrhea may slow antibiotic resistance, but verification remains challenging for many sexually transmitted disease (STD) programs due to increased laboratory case reporting and decreased provider reporting. The objectives of this study were to document current reported levels of correct treatment of gonorrhea and to identify approaches and barriers to verifying treatment.

Methods: We reviewed funding opportunity reports for the Centers for Disease Control and Prevention's directly funded STD programs and conducted key-informant interviews to elicit further treatment verification details.

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The Program Cost of a Brief Video Intervention Shown in Sexually Transmitted Disease Clinic Waiting Rooms.

Sex Transm Dis

January 2016

From the *Centers for Disease Control and Prevention, Atlanta, GA; †Education Development Center, Waltham, MA; ‡Rietmeijer Consulting, LLC, Denver, CO; §California State University, Long Beach, Long Beach, CA; and ¶University of California, Los Angeles, Los Angeles, CA.

Background: Patients in sexually transmitted disease (STD) clinic waiting rooms represent a potential audience for delivering health messages via video-based interventions. A controlled trial at 3 sites found that patients exposed to one intervention, Safe in the City, had a significantly lower incidence of STDs compared with patients in the control condition. An evaluation of the intervention's cost could help determine whether such interventions are programmatically viable.

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Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults.

N Engl J Med

July 2015

From the Centers for Disease Control and Prevention, Atlanta (S.J., A.M.B., C.R., M.L., S.L., J.M.W., J.M.K., D.E., E.S., L.A.H., L.F.); Vanderbilt University School of Medicine (W.H.S., C.G.G., J.D.C., F.C., D.J.W., Y.Z., K.M.E.) and University of Tennessee Health Science Center-Saint Thomas Health (C.T.), Nashville, and Le Bonheur Children's Hospital (S.R.A., J.A.M.), University of Tennessee Health Science Center (S.R.A., J.A.M.), and St. Jude Children's Research Hospital (J.A.M.), Memphis - all in Tennessee; Northwestern University Feinberg School of Medicine (R.G.W., E.J.A., D.M.C., C.Q., E.M.H., H.K.D., G.W.W.), John H. Stroger, Jr., Hospital of Cook County (S.F.), and Rush University Medical Center (R.B.) - all in Chicago; University of Utah Health Sciences Center, Salt Lake City (K.A., A.T.P.); and University of Western Australia, Perth (G.W.W.).

Background: Community-acquired pneumonia is a leading infectious cause of hospitalization and death among U.S. adults.

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Comparison of Antimicrobial Susceptibility of Urogenital Neisseria gonorrhoeae Isolates Obtained From Women and Men.

Sex Transm Dis

August 2015

From the *Centers for Disease Control and Prevention, Atlanta, GA; †University of Arkansas for Medical Sciences, Little Rock, AR; ‡San Francisco Department of Health, San Francisco, CA; §University of Pittsburgh and Allegheny County Health Department, Pittsburgh, PA; ¶County of Los Angeles, Department of Public Health, Los Angeles, CA; ∥FHI360, Durham, NC; **Johns Hopkins University School of Medicine, Baltimore, MD; and ††University of Alabama at Birmingham and Jefferson County Department of Health, Birmingham, AL.

Background: The US system for gonococcal antimicrobial susceptibility surveillance monitors trends exclusively among men with urethral infection, the population from whom the yield of gonococcal culture is highest. Little is known about the susceptibility of female urogenital isolates, and it is unclear whether gonococcal susceptibility among men who report sex exclusively with women (MSW) is representative of susceptibility among women.

Methods: Using isolates collected during a recent treatment trial in 5 US cities, we performed a secondary analysis to compare antimicrobial susceptibilities of Neisseria gonorrhoeae urogenital isolates obtained from women, MSW, and men who have sex with men (MSM).

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Purpose: To examine, at the population level, health behaviors, comorbidities, and health-related quality of life among colorectal cancer (CRC) survivors compared with other cancer survivors and persons without cancer.

Methods: We used data from the 2009 and 2010 Behavioral Risk Factor Surveillance System cancer survivor modules. We calculated descriptive statistics, conducted chi-square tests for comparisons, and used multivariable logistic regression analysis to compare CRC survivors with other cancer survivors and persons without cancer.

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