26 results match your criteria: "From Stanford University School of Medicine[Affiliation]"
Perioperative Pembrolizumab for Early-Stage Non-Small-Cell Lung Cancer.
N Engl J Med
August 2023
From Stanford University School of Medicine, Stanford Cancer Institute, Stanford, CA (H.W.); Centre Hospitalier de l'Université de Montréal (M.L.) and McGill University Health Centre (J.D.S.) - both in Montreal; Kanagawa Cancer Center, Yokohama (T.K.), and National Cancer Center Hospital East, Kashiwa (M.T.) - both in Japan; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea (S.-H.L.); the National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (S.G.), and Beijing Cancer Hospital, Peking University (K.-N.C.) - both in Beijing; University Hospitals Leuven, Leuven, Belgium (C.D.); Hospital de la Santa Creu i Sant Pau, Barcelona (M.M.), and Hospital Universitario Insular de Gran Canaria, Universidad de Las Palmas de Gran Canaria, Las Palmas (D.R.-A.) - both in Spain; Zentralklinik Bad Berka, Bad Berka, Germany (E.E.); Sanatorio Parque, Cordoba, Argentina (G.L.M.); Hôpital d'Instruction des Armées Sainte-Anne, Toulon, France (O.B.); Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York (J.E.C.); the Department of Oncology, University of Turin, Azienda Ospedaliero-Universitaria San Luigi Gonzaga di Orbassano, Turin, Italy (S.N.); and Merck, Rahway, NJ (J.Y., S.M.K., A.S.).
Background: Among patients with resectable early-stage non-small-cell lung cancer (NSCLC), a perioperative approach that includes both neoadjuvant and adjuvant immune checkpoint inhibition may provide benefit beyond either approach alone.
Methods: We conducted a randomized, double-blind, phase 3 trial to evaluate perioperative pembrolizumab in patients with early-stage NSCLC. Participants with resectable stage II, IIIA, or IIIB (N2 stage) NSCLC were assigned in a 1:1 ratio to receive neoadjuvant pembrolizumab (200 mg) or placebo once every 3 weeks, each of which was given with cisplatin-based chemotherapy for 4 cycles, followed by surgery and adjuvant pembrolizumab (200 mg) or placebo once every 3 weeks for up to 13 cycles.
Corporate Investors in Primary Care - Profits, Progress, and Pitfalls.
N Engl J Med
January 2023
From Stanford University School of Medicine (S.S.) and Stanford Law School (H.R.-L.) - both in Stanford, CA; and the Center for Law, Health, and Society, Georgia State University College of Law, Atlanta (E.C.F.B.).
The Importance of Context in Covid-19 Vaccine Safety.
N Engl J Med
September 2021
From Stanford University School of Medicine, Stanford, CA.
Vadadustat in Patients with Anemia and Non-Dialysis-Dependent CKD.
N Engl J Med
April 2021
From Stanford University School of Medicine, Palo Alto, CA (G.M.C., E.F.L.); Renal Associates, San Antonio (P.E.P.), U.S. Renal Care, Plano (G.A.B.), Baylor University Medical Center, Baylor Heart and Vascular Hospital, Baylor Heart and Vascular Institute, Dallas (P.A.M.), and the Section of Nephrology, Baylor College of Medicine, Houston (W.C.W.) - all in Texas; Akebia Therapeutics, Cambridge (Y.M.K.F., S.B., Z.K., W.L., B.J.M., A.S., D.L.V.), and the Division of Nephrology, Tufts Medical Center, Tufts University School of Medicine, Boston (M.J.S.) - both in Massachusetts; the Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis (R.A.); Excellentis Clinical Trial Consultants, George, South Africa (S.A.); Bihor County Hospital Oradea, Oradea, Romania (G.B.); Qway Research, Hialeah, FL (F.P.C.); the Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom (A.G.J.); the Department of Medicine, Vanderbilt University Medical Center, Nashville (M.J.K.); Firma Clinical Research, Hunt Valley (T.L.), and the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore (K.M.) - both in Maryland; the Department of Medicine, Memorial University of Newfoundland, St. John's, Canada (P.S.P.); the Division of Nephrology and Hypertension, University of North Carolina Kidney Center, Chapel Hill, and the W.G. (Bill) Hefner Veterans Affairs Medical Center, Salisbury - both in North Carolina (P.R.-C.); the Division of Nephrology, New York-Presbyterian Queens, Flushing (B.S.); Firma Clinical Research, Chicago (C.T.); Emory University School of Medicine, Atlanta (J.T.); Statistics Collaborative, Washington, DC (K.A.W., J.W.); and the Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin (K.-U.E.).
Article Synopsis
- * The study involved two large Phase 3 clinical trials focusing on patients with low hemoglobin levels; the main goal was to assess the safety of vadadustat compared to darbepoetin, specifically looking at major cardiovascular events.
- * Results showed that vadadustat did not meet the safety benchmark compared to darbepoetin, as indicated by a higher hazard ratio for major adverse cardiovascular events, and there was minimal difference in hemoglobin improvement between the two treatments.
The Missing Piece - SARS-CoV-2 Testing and School Reopening.
N Engl J Med
December 2020
From Stanford University School of Medicine (Y.R., M.M.M.) and Stanford Law School (M.M.M.), Stanford, CA.
The Unexpected Volunteer.
J Am Board Fam Med
July 2021
From Stanford University School of Medicine, Stanford, CA.
In this narrative account, the author, a medical student, describes his encounters with several inpatients at a community hospital. He becomes acquainted with a patient's son, who, initially withdrawn, over the course of his mother's hospitalizations transforms into a compassionate volunteer. This change is made especially evident when the author meets another patient who recognizes the volunteer and reveals his very different past.
View Article and Find Full Text PDFVISUAL VIGNETTE.
Endocr Pract
December 2019
From Stanford University School of Medicine, Department of Otolaryngology-Head and Neck Surgery, Stanford, California.
Quality of Randomized Controlled Trials for Surgical Treatment of Carpal Tunnel Syndrome: A Systematic Review.
Plast Reconstr Surg
March 2019
From Stanford University School of Medicine; and the Division of Plastic and Reconstructive Surgery, Stanford Health Care.
Background: Randomized controlled trials are considered the gold standard in evidence-based medicine. The authors conducted a systematic review to evaluate the quantity, quality, and trends of randomized controlled trials that assess surgical treatment of carpal tunnel syndrome.
Methods: The authors identified randomized controlled trials comparing two or more surgical interventions for carpal tunnel syndrome in PubMed, Cochrane, Scopus, Google Scholar, and Clinicaltrials.
Toward an Effective Innovation Agenda.
N Engl J Med
March 2019
From Stanford University School of Medicine, Stanford, CA (K.A.S.); and Duke University School of Law, Durham, NC (B.D.R.).
Lymphedema after Breast Cancer Treatment.
N Engl J Med
November 2018
From Stanford University School of Medicine, Stanford, CA.
To Be Guided by Instinct.
N Engl J Med
September 2018
From Stanford University School of Medicine, Stanford, CA.
Video NeuroImages: Paraneoplastic spinal myoclonus associated with Caspr2 antibodies.
Neurology
April 2018
From Stanford University School of Medicine (H.H.); and Department of Neurology and Neurological Sciences (N.M.M., S.A., S.J., C.A.G.), Stanford University Medical Center, CA.
Novel Metrics for Improving Professional Fulfillment.
Ann Intern Med
November 2017
From Stanford University School of Medicine, Stanford Health Care, and Stanford Children's Health, Palo Alto, California; American Medical Association, Chicago, Illinois; and University HealthCare Alliance, Newark, California.
Pain Catastrophizing Moderates Relationships between Pain Intensity and Opioid Prescription: Nonlinear Sex Differences Revealed Using a Learning Health System.
Anesthesiology
July 2017
From Stanford University School of Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford Systems Neuroscience and Pain Laboratory, Palo Alto, California.
Background: Pain catastrophizing is a maladaptive response to pain that amplifies chronic pain intensity and distress. Few studies have examined how pain catastrophizing relates to opioid prescription in outpatients with chronic pain.
Methods: The authors conducted a retrospective observational study of the relationships between opioid prescription, pain intensity, and pain catastrophizing in 1,794 adults (1,129 women; 63%) presenting for new evaluation at a large tertiary care pain treatment center.
Handgun Acquisitions in California After Two Mass Shootings.
Ann Intern Med
May 2017
From Stanford University School of Medicine and Stanford Law School, Stanford, and School of Medicine, University of California, Davis, California, and Monash University, Clayton, Victoria, Australia.
Background: Mass shootings are common in the United States. They are the most visible form of firearm violence. Their effect on personal decisions to purchase firearms is not well-understood.
View Article and Find Full Text PDFPoint-of-Care Ultrasound in Internal Medicine: Challenges and Opportunities for Expanding Use.
South Med J
December 2016
From Stanford University School of Medicine, Stanford, California.
Treatment of Muscle-Invasive Bladder Cancer in Older Patients.
Am Soc Clin Oncol Educ Book
January 2017
From Stanford University School of Medicine, Stanford, CA.
Treatment of muscle-invasive bladder cancer in older patients is challenging. Definitive therapy of localized disease requires either surgery or radiation therapy, ideally combined with systemic chemotherapy. However, current population data suggest that less than half of patients older than age 70 are offered such treatments.
View Article and Find Full Text PDFPrevalence and Characteristics of Physicians Prone to Malpractice Claims.
N Engl J Med
January 2016
From Stanford University School of Medicine and Stanford Law School, Stanford, CA (D.M.S., M.M.M.); Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia (M.M.B., M.J.S.); and the Health Resources and Services Administration, Department of Health and Human Services, Rockville, MD (H.S.).
Background: The distribution of malpractice claims among physicians is not well understood. If claim-prone physicians account for a substantial share of all claims, the ability to reliably identify them at an early stage could guide efforts to improve care.
Methods: Using data from the National Practitioner Data Bank, we analyzed 66,426 claims paid against 54,099 physicians from 2005 through 2014.
Opioids in Psychiatric Disorders: Back to the Future?
Am J Psychiatry
June 2016
From Stanford University School of Medicine, Stanford, Calif.
Long-Term Outcomes of Rectosigmoid Neocolporrhaphy in Male-to-Female Gender Reassignment Surgery.
Plast Reconstr Surg
August 2015
Stanford, Calif.; and Chicago, Ill. From Stanford University School of Medicine; the Division of Plastic Surgery, Department of Surgery, Stanford University Medical Center; and Northwestern University Feinberg School of Medicine.
Background: Favorable outcomes of rectosigmoid neocolporrhaphy have previously been reported. Unfortunately, rectosigmoid transfers are still perceived negatively, usually relegated to secondary vaginoplasties. This study aims to provide an objective investigation into the safety and efficacy of rectosigmoid neocolporrhaphy for vaginoplasty in male-to-female transsexual patients.
View Article and Find Full Text PDFRole of somatostatin analogues in the treatment of neuroendocrine tumors.
J Natl Compr Canc Netw
January 2015
From Stanford University School of Medicine, Stanford, California.
Neuroendocrine tumors (NETs) are rare epithelial neoplasms with neuroendocrine differentiation that most commonly originate in the lungs and gastrointestinal tract. Many patients have advanced disease not amenable to surgery or local management. Some tumors also secrete amines, such as serotonin, that lead to syndromes of hormone excess, such as diarrhea and flushing.
View Article and Find Full Text PDFMedical laboratories in sub-Saharan Africa that meet international quality standards.
Am J Clin Pathol
June 2014
the Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
Objectives: A recent survey of laboratories in Kampala, Uganda, demonstrated that only 0.3% of laboratories (3/954) met international quality standards. To benchmark laboratory quality throughout the rest of sub-Saharan Africa (SSA), we compiled a list of SSA laboratories meeting international quality standards.
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