2 results match your criteria: "Friendship Hospital to Urumqi[Affiliation]"

Background: The aim of the present study is to determine the association of serum lipid level in the above 55-year-old age elderly with ischemic stroke (IS) in Xinjiang regions, China.

Methods: 408 patients with IS and 347 healthy individuals as control in the ≥55-year-old elderly were selected for the present study in Xinjiang province of China from July 2010 to July 2012. Patients were divided into different groups according to the IS subtypes (large-artery atherosclerosis, LAA; cardio-aortic embolism CE; small-artery occlusion, SAO), plague stability, hypertension and diabetes.

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Article Synopsis
  • The study investigates the link between specific genetic polymorphisms related to lipid metabolism and ischemic stroke in the Han and Uighur populations of Xinjiang, China.
  • Genetic analysis was performed on 400 ischemic stroke patients and 347 healthy individuals, focusing on genes like ApoA5, LPL, CETP, and LDL-R, using advanced genotyping techniques.
  • Significant associations were found between ischemic stroke and LDLR rs688 in both populations, particularly in the Han group, while no notable link was observed in the Uighur group; the results suggest a complicated relationship between these genetic factors and stroke risk.
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