9 results match your criteria: "Friedrich-Loeffler-Institut - Federal Research Institute for Animal Health (FLI)[Affiliation]"

Paratuberculosis in South American camelids: two independent cases in alpacas in Germany.

BMC Vet Res

December 2024

Chemical and Veterinary Investigation Office Westphalia, Arnsberg, Germany.

Background: Paratuberculosis, caused by Mycobacterium avium subspecies paratuberculosis (MAP), is a chronic granulomatous enteritis that affects domestic and wild ruminants and camelids. The disease has rarely been reported in alpacas in Germany. This publication describes epidemiologically independent cases of paratuberculosis in two alpacas in Germany.

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Experimental arboviral infection of mosquito larvae: A novel approach for vector competence studies.

J Virol Methods

January 2025

Friedrich-Loeffler-Institut - Federal Research Institute for Animal Health (FLI), Institute of Infectology, Südufer 10, Greifswald, Insel Riems 17493, Germany.

Vector competence studies in mosquitoes present valuable opportunities to explore arboviral transmission and virus-vector interactions. However, oral infection studies in mosquitoes can be challenging. An alternative approach is to infect mosquitoes during their aquatic larval stage, resulting in the emergence of infected adults.

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Article Synopsis
  • * Tick nymphs were collected in 2009/2010 and 2019 for pathogen analysis, revealing fluctuating prevalence rates of various species over the decade.
  • * While some pathogens showed minimal significant changes in prevalence, the need for ongoing research that considers various ecological factors is emphasized to better understand the dynamics of tick-borne diseases.
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Generation of transgenic birds can be achieved by temporal suppression of endogenous spermatogenesis in males prior to primordial germ cell implantation. One of many established methods to induce male sterility is the intraperitoneal injection of busulfan, an alkylating agent. Nevertheless, the use of busulfan injections, which may also affect hematopoietic stem cells, carries the risk of potential lethality in animals.

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Antimicrobial resistance (AMR) is considered one of the greatest threats to both human and animal health. Efforts to address AMR include implementing antimicrobial stewardship programs and introducing alternative treatment options. Nevertheless, effective treatment of infectious diseases caused by bacteria will still require the identification and development of new antimicrobial agents.

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In the northernmost German federal state Schleswig-Holstein, populations of European brown hares () show diverse densities and varying courses over the years. To examine differences in pathomorphological findings and infectious diseases as possible reasons for varying population dynamics, we assessed 155 hunted hares from three locations in Schleswig-Holstein from 2016 to 2020. We investigated the association of location, year, age, and sex of animals to certain pathomorphological findings and infectious diseases.

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The European brown hare () is a quite adaptable species, but populations have been decreasing for several decades in different countries, including Germany. To investigate infectious diseases as possible influences on observed population decline in the German federal state Schleswig-Holstein, 118 deceased free-ranging European brown hares were collected between 2017 and 2020 and underwent detailed postmortem examination with extended sampling. Infectious diseases were a major cause of death (34.

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Genomic epidemiology of subsp. from Germany.

Front Vet Sci

January 2023

Friedrich-Loeffler-Institut-Federal Research Institute for Animal Health (FLI), Institute of Bacterial Infections and Zoonoses, Jena, Germany.

Article Synopsis
  • - The text discusses bovine genital campylobacteriosis (BGC), a disease causing major reproductive issues in cattle and recognized by the World Organization for Animal Health, leading to economic challenges and strict control measures in various countries.
  • - A study conducted in Germany analyzed 63 BGC strains collected over 30 years using whole-genome sequencing, revealing a genetically conserved population with geographical clusters.
  • - Results indicate that BGC control efforts in Germany have been effective, with no reported outbreaks since 2015, and suggest that the German strains share a common lineage that likely originated in the 19th century.
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Collaboration across sectors, disciplines and countries is a key concept to achieve the overarching One Health (OH) objective for better human, animal and environmental health. Differences in terminology and interpretation of terms are still a significant hurdle for cross-sectoral information exchange and collaboration within the area of OH including One Health Surveillance (OHS). The development of the here described glossary is a collaborative effort of three projects funded within the One Health European Joint Programme (OHEJP).

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