1 results match your criteria: "France. Electronic address: jessica.sabourin@universite-paris-saclay.fr.[Affiliation]"
Cell Calcium
May 2024
Inserm, UMR-S 1180, Signalisation et Physiopathologie Cardiovasculaire, Université Paris-Saclay, 91400 Orsay, France. Electronic address:
The stromal interaction molecules (STIMs) are the sarcoplasmic reticulum (SR) Ca sensors that trigger store-operated Ca entry (SOCE) in a variety of cell types. While STIM1 isoform has been the focus of the research in cardiac pathophysiology, the function of the homolog STIM2 remains unknown. Using Ca imaging and patch-clamp techniques, we showed that knockdown (KD) of STIM2 by siRNAs increased SOCE and the I current in neonatal rat ventricular cardiomyocytes (NRVMs).
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