Time to Refine Prostate Cancer Epidemiology: Defining New Endpoints for Effective Screening and Causal Epidemiological Studies.

Current epidemiological indicators reflect the prevalence of prostate-specific antigen (PSA) testing rather than the actual incidence of clinically significant prostate cancer. These indicators are also biased because of the variability of the PSA test. We therefore need to adopt new reliable criteria in causal epidemiological studies and screening programs.

Mechanical Circulatory Support for Massive Pulmonary Embolism.

Up to 50% of patients with pulmonary embolism (PE) experience hemodynamic instability and approximately 70% of patients who die of PE experience an accelerated cascade of symptoms within the first hours of onset of symptoms, thus necessitating rapid evaluation and intervention. Venoarterial extracorporeal membrane oxygenation and other ventricular assist devices, depending on the hemodynamic derangements present, may be used to stabilize patients with massive PE refractory to initial therapies or with contraindications to other interventions. Given the abnormalities in both pulmonary circulation and gas exchange caused by massive PE, venoarterial extracorporeal membrane oxygenation may be considered the preferred form of mechanical circulatory support for most patients.

Ecosystem Size Mediates the Effects of Resource Flows on Species Diversity and Ecosystem Function at Different Scales.

Ecosystem size and spatial resource flows are key factors driving species diversity and ecosystem function. However, the question of whether and how these drivers interact has been largely overlooked. Here, we investigated how ecosystem size asymmetry affects species diversity and function of two-patch meta-ecosystems connected through flows of nonliving resources.

First records of and from Senegal (Selaginellaceae).

Background: The monogeneric family Selaginellaceae is made up of about 700 species distributed throughout the world, but the most concentrated part is in tropical and subtropical areas. According to the most recent infrageneric classification of the genus , six or seven subgenera can be recognised and perhaps 700 species. The genus is monophyletic, cosmopolitan, characterised by the presence of rhizophores, ligulated leaves and has a reniform adaxial sporangia with two type of spores (heterospory).

Childhood interstitial lung disease survivors in adulthood: a European collaborative study.

Background: Interstitial lung disease (ILD) is rarer in children (chILD) than adults, but with increasing diagnostic awareness, more cases are being discovered. chILD prognosis is often poor, but increasing numbers are now surviving into adulthood.

Aim: To characterize chILD-survivors and identify their impact on adult-ILD centers.

Partners experiences of caesarean deliveries in the operating room.

Objective: To describe the experiences of partners accompanying pregnant women during a caesarean section and to identify factors which influence the experiences.

Methods: It is a prospective, single-center, observational study which included all partners of women who underwent a planned or an unplanned caesarean section in a maternity hospital during a two months period (1st November 2020 - 1st January 2021). The outcome was evaluated by a standardized questionnaire: the first-time father questionnaire (FTFQ) (1).

A Comparative Analysis of Satellite-Derived CO Retrievals During the 2020 Wildfires in North America.

In September 2020, the Western United States experienced anomalously severe wildfires that resulted in carbon monoxide (CO) emissions almost three times the 2001-2019 average. In this study, we investigate the influence of wildfires on atmospheric carbon monoxide (CO) variability through a comparative analysis of observations from the Measurements of Pollution in the Troposphere (MOPITT), the Infrared Atmospheric Sounding Interferometer (IASI), and the Tropospheric Monitoring Instrument (TROPOMI). Our focus is on the North American domain, aiming to understand the differences among these products.

The Political Glass Cliff: When Ethnic, Racial and Immigration Minority Participants Choose Minority Candidates for Hard-To-Win Seats.

Atypical political candidates, such as those from ethnic, racial and immigration (ERI) minorities (vs. majority), are more likely to be chosen for hard-to-win seats than easy-to-win seats, a phenomenon known as the political glass cliff. This research aimed to uncover how the ERI status of decision makers played a role in this process.

Probing the water adsorption and stability under steam flow of Zr-based metal-organic frameworks using Zr solid-state NMR spectroscopy.

The stability of metal-organic frameworks (MOFs) in the presence of water is crucial for a wide range of applications, including the production of freshwater, desiccation, humidity control, heat pumps/chillers and capture and separation of gases. In particular, their stability under steam flow is essential since most industrial streams contain water vapor. Nevertheless, to the best of our knowledge, the stability under steam flow of Zr-based MOFs, which are among the most widely studied MOFs, has not been investigated so far.

Inflammatory Waldenström Macroglobulinemia is associated with clonal hematopoiesis: a multicentric cohort.

Inflammation in Waldenström Macroglobulinemia (iWM) predicts outcomes after immuno-chemotherapy and BTK inhibitors, but its origin is unknown. Here, we unravel increased clonal hematopoiesis in iWM patients (61% versus 23% in non-inflammatory WM), suggesting a contribution of environmental cells to iWM.

SWAP algorithm for lattice spin models.

We adapted the SWAP molecular dynamics algorithm for use in lattice Ising spin models. We dressed the spins with a randomly distributed length and we alternated long-range spin exchanges with conventional single spin flip Monte Carlo updates, both accepted with a stochastic rule which respects detailed balance. We show that this algorithm, when applied to the bidimensional Edwards-Anderson model, speeds up significantly the relaxation at low temperatures and manages to find ground states with high efficiency and little computational cost.

ArcaNN: automated enhanced sampling generation of training sets for chemically reactive machine learning interatomic potentials.

The emergence of artificial intelligence is profoundly impacting computational chemistry, particularly through machine-learning interatomic potentials (MLIPs). Unlike traditional potential energy surface representations, MLIPs overcome the conventional computational scaling limitations by offering an effective combination of accuracy and efficiency for calculating atomic energies and forces to be used in molecular simulations. These MLIPs have significantly enhanced molecular simulations across various applications, including large-scale simulations of materials, interfaces, chemical reactions, and beyond.

Substantial Insect Herbivory in a South African Savanna-Forest Mosaic: A Neglected Topic.

Insect herbivory plays a crucial role in shaping plant communities in many terrestrial ecosystems. However, in African savannas, insect herbivory has been relatively understudied compared to large mammalian herbivory. In this study, we examined the impact of insect herbivory, focusing on leaf chewers and miners, in a South African savanna-forest mosaic (including patches of forest, thicket and savanna) in Hluhluwe iMfolozi Park, South Africa.

Évaluation de la mise en œuvre des missions de service sanitaire en santé sexuelle en Île-de-France.

Contexte: Le service sanitaire français, réalisé par des étudiants en santé (3 année), est un programme de promotion de la santé (PS) récent qui est encore peu évalué.

Objectif: Cette étude s'est intéressée au service mis en place dans la filière médecine à l'université Paris Cité, sur la thématique santé sexuelle. L'objectif de l'étude est d'évaluer des interventions réalisées par les étudiants en termes pédagogiques et en termes de bonnes pratiques en PS, sur les plans suivants : éthique, qualité du contenu et communication.

Long-term outcome of 2-year survivors after allogeneic hematopoietic cell transplantation for acute leukemia.

Information on late complications in patients with acute leukemia who have undergone allogeneic hematopoietic cell transplantation (HCT) is limited. We performed a left-truncated analysis of long-term survival in patients with acute leukemia who were alive and disease-free 2 years after HCT. We included 2701 patients with acute lymphoblastic leukemia (ALL) and 9027 patients with acute myeloid leukemia (AML) who underwent HCT between 2005 and 2012.

Description of sp. nov., a new hard tick species (Acari, Ixodidae) collected from mouse-eared bats (Vespertilionidae, ) in Vietnam.

Historically, for more than one and a half centuries, only one so-called "long-legged bat tick" species, i.e., Koch was known to science.

Towards a history of global hospital governance, late nineteenth century to mid-twentieth century: a contribution to a history yet to be written.

This article draws on the recent historiography in international relations and global health, as well as selected archives, to propose some milestones for a history of global hospital governance from the late nineteenth to the mid-twentieth century. How can we identify a system of hospital governance, including formal and informal arrangements, on a global or sub-global scale? Through the lens of the International Hospital Association, founded in 1931, we highlight the significance of internationalization processes, relationships with other international organizations, transnational interpersonal networks, and forces structuring innovation. This document provides a preliminary starting point for discussion and encourages further research.

Unlocking metal-ligand cooperative catalytic photochemical benzene carbonylation: a mechanistic approach.

A key challenge in green synthesis is the catalytic transformation of renewable substrates at high atom and energy efficiency, with minimal energy input (Δ ≈ 0). Non-thermal pathways, , electrochemical and photochemical, can be used to leverage renewable energy resources to drive chemical processes at well-defined energy input and efficiency. Within this context, photochemical benzene carbonylation to produce benzaldehyde is a particularly interesting, albeit challenging, process that combines unfavorable thermodynamics (Δ° = 1.