1 results match your criteria: "France (J.D.) Réunion Island University-affiliated Hospital[Affiliation]"
Reconstituted High-density Lipoprotein Therapy Improves Survival in Mouse Models of Sepsis.
Anesthesiology
April 2020
From Réunion Island University, French Institute of Health and Medical Research (INSERM) U1188, Diabetes atherothrombosis Réunion Indian Ocean (DéTROI), CYROI Plateform, Saint-Denis de La Réunion, France (S.T., J.Y-S., C.P., M.B., D.C., O.M.) Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Anesthesiology and Critical Care Medicine, Bichat-Claude Bernard Hospital, Paris, France (S.T., C.G., N.Z., P.M.) INSERM U1148, Laboratory for Vascular Translational Science, Paris France (C.G., N.Z., L.L.) Réunion Island University, INSERM U1187, CNRS (National Center for Scientific Research) 9192, IRD (Institute for Research and Development) 249, PIMIT Laboratory, Infectious Processes in Tropical Island Environment, CYROI Plateform 2, Saint-Denis de La Réunion, France (W.V.) INSERM U1152, Physiopathology and Epidemiology of Respiratory Diseases, Paris, France (P.M.) INSERM U1137, Infection, Antimicrobials, Modelling, Evolution, Paris, France (E.D.) AP-HP, Department of Anesthesiology and Critical Care Medicine, Paris-Sud Hospitals, Paris-Sud University, Bicêtre Hospital, Le Kremlin-Bicêtre, France (J.D.) Clinical Research Unit (Bio-CANVAS: biomarkers in CardioNeuroVascular DISEASES) U942, Paris, France (J.D.) Réunion Island University-affiliated Hospital, France (D.C., O.M.).
Background: High-density lipoproteins exert pleiotropic effects including antiinflammatory, antiapoptotic, and lipopolysaccharide-neutralizing properties. The authors assessed the effects of reconstituted high-density lipoproteins (CSL-111) intravenous injection in different models of sepsis.
Methods: Ten-week-old C57BL/6 mice were subjected to sepsis by cecal ligation and puncture or intraperitoneal injection of Escherichia coli or Pseudomonas aeruginosa pneumonia.