1,077,179 results match your criteria: "France; University Pierre et Marie Curie Paris VI[Affiliation]"

Increasing consumer concerns underscore the importance of verifying the practices and origins of food, especially certified premium products. The aim of this study was to evaluate the ability of Fourier-transform mid-infrared (FT-MIR) spectroscopy to authenticate animal welfare parameters, farming practices, and dairy systems. Data on farm characteristics were obtained from the Parmigiano Reggiano Consortium in northern Italy.

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It is currently uncertain how selection of more efficient animals might impact other traits such as resilience (which, in this context, is defined as the ability of an animal to sustain or revert quickly to its previous production level and health status after a disturbance), especially in small ruminants. However, improving, or at least maintaining, resilience is of utmost importance to ensure livestock production in the face of external perturbances, which are expected to become more prevalent in the near future due to climate change and global instability. This study was conducted to investigate whether a nutritional challenge consisting of animals receiving only 70% of their voluntary feed intake (DMI) for 26 d, might differentially affect the response of high- and low-feed efficiency (FE) sheep.

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Despite numerous studies on fetal therapy for myelomeningoceles (MMC), the pathophysiology of this malformation remains poorly understood. This study aimed to analyze the biochemical profile and proteome of amniotic fluid (AF) supernatants from MMC fetuses to explore the prenatal pathophysiology. Biochemical analysis of 61 AF samples from MMC fetuses was compared with 45 healthy fetuses' samples.

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Transcranial direct current stimulation in patients with depression: An electric field modeling meta-analysis.

J Affect Disord

January 2025

Mondor University Hospitals, INSERM U955, Institut Mondor de La Recherche Biomédicale (IMRB), University of Paris Est Créteil, Équipe Neuropsychiatrie Translationnelle, Créteil, France; NeuroSpin, Neuroimaging Platform, CEA, UNIACT Lab, PsyBrain Team, Saclay, France. Electronic address:

Transcranial Direct Current Stimulation (tDCS) has shown potential in modulating cortical activity and treating depression. Despite its promise, variability in electrode montage configurations and electric field strength across studies has resulted in inconsistent outcomes. Traditional meta-analytic methods assessing the effect of tDCS in depression typically do not compare tDCS montage and the anatomical distribution of electric field, which is a major source of inter-experimental variability.

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Interplay of acidic residues in the proton channel of E. coli cytochrome bd-I oxidase to promote oxygen reduction and NO release.

Biochim Biophys Acta Bioenerg

January 2025

Laboratoire de Bioélectrochimie et Spectroscopie, UMR 7140, Chimie de la Matière Complexe, Université de Strasbourg-CNRS 4, Rue Blaise Pascal, 67081 Strasbourg, France; Institut universitaire de France (IUF), France. Electronic address:

The reduction of oxygen to water is crucial to life under aerobic conditions. Cytochrome bd oxidases perform this reaction with a very high oxygen affinity. Members of this protein family are solely found in prokaryotes and some archaea playing an important role in bacterial virulence and antibiotic resistance.

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Introduction: Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous condition that includes a spectrum of oral clinical manifestations ranging from mild painless white lesions to painful erosions and ulcers. The purpose of this European multicenter study is to describe the general characteristics of OLP lesions, the clinical and histopathological diagnosis, and the management of OLP at different European Oral Medicine and Maxillofacial Surgery centers, in order to minimize selections biases and provide information about the current trends in the treatment of OLP across Europe.

Materials And Methods: Data and histopathological records of patients with OLP were retrospectives revised and only those patients that fulfilled the diagnostic criteria from the 2016 position paper by American Academy of Oral and Maxillofacial Pathology were included.

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Leishmaniasis is a neglected tropical disease caused by protozoans of the Leishmania genus, against which no effective treatment or control is available. Like other eukaryotes, parasite telomeres are maintained by telomerase, a ribonucleoprotein complex vital for genome stability. Its protein component, TERT (telomerase reverse transcriptase), presents four structural and functional domains, with the TEN (Telomerase N-terminal) and TRBD (Telomerase RNA-binding) located at its N-terminal.

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Water scarcity in the Mediterranean area has increased the number of intermittent rivers. Recently, hyporheic zones (HZ) of intermittent rivers have gained attention since a substantial part of the stream's natural purification capacity is located within these zones. Thus, understanding the flow dynamics in HZs is crucial for gaining insights into the degradation of organic micropollutants.

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Identification of serum IFN-α and BAFF levels as potential biomarkers of activity and severity in cutaneous lupus erythematosus.

J Invest Dermatol

January 2025

Sorbonne Université, Faculté de médecine, Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Dermatologie et Allergologie, Hôpital Tenon, Paris, France; Sorbonne Université, Inserm, Centre d'Immunologie et des Maladies Infectieuses-Paris (CIMI PARIS), INSERM U1135, Paris, France.

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The aim of the study was to identify distinct trajectories of perceived stress and control in athletes across a season of sports competitions and whether these trajectory memberships could be predicted by subdimensions of the emotional intelligence (EI). Latent class growth analyses were performed on a five-stage longitudinal measurement plan (to cover the entire sporting season). Four hundred fifteen athletes answered to the Brief Emotional Intelligence Scale, the Mastery Scale, the Perceived Stress Scale, and the Attainment of Sport Achievement Goal Scale.

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Evaluating interface pressure in a lower-limb prosthetic socket: Comparison of FEM and experimental measurements on a roll-over simulator.

J Biomech

January 2025

Arts et Métiers Institute of Technology, Université Sorbonne Paris Nord, IBHGC - Institut de Biomécanique Humaine Georges Charpak, HESAM Université, 151 boulevard de l'Hôpital, 75013 Paris, France. Electronic address:

Improper socket fitting in lower-limb prostheses can lead to significant complications, including pain, skin lesions, and pressure ulcers. Current suspension and socket design practices rely predominantly on visual inspection of the residual limb and patient feedback. Monitoring stress distribution at the residual limb/socket interface offers a more objective approach.

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Introduction: After a pandemic outbreak, designing and implementing an effective vaccine supply chain is key. The last-mile vaccine delivery (LMVD) - the last stage of the vaccine supply chain - is of particular importance. LMVD design choices, such as the delivery mode (e.

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Toward a comprehensive profiling of alternative splicing proteoform structures, interactions and functions.

Curr Opin Struct Biol

January 2025

Sorbonne Université, CNRS, IBPS, Laboratory of Computational and Quantitative Biology (LCQB), UMR 7238, 75005 Paris, France.

The mRNA splicing machinery has been estimated to generate 100,000 known protein-coding transcripts for 20,000 human genes (Ensembl, Sept. 2024). However, this set is expanding with the massive and rapidly growing data coming from high-throughput technologies, particularly single-cell and long-read sequencing.

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Perfluorooctanesulfonic acid (PFOS) is one of the most investigated Per- and polyfluoroalkyl substances (PFAS) for being the strongest compound to eliminate and having adverse health concerns. In this work, we have conducted the sonochemical treatment of PFOS simulated water under high (500 kHz) and low (22 kHz) frequencies while monitoring the operational parameters via an integrated sonochemical system. The integrated advanced sonochemical system includes software to monitor treatment power, solution temperature and frequency while allowing distinctive control of the reaction conditions.

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Spontaneous rupture of aortic aneurysm due to Listeria monocytogenes in an immunocompetent patient and review of the literature.

Diagn Microbiol Infect Dis

December 2024

Laboratoire de Biologie Médicale, GCS Biologie85, CHD Vendée, 85000 LA ROCHE SUR YON, France. Electronic address:

Infectious aneurysms represent <5 % of cases [1] with a crucial and challenging diagnosis. Staphylococcus, Streptococcus, Enterobacteria are mostly involved but unusual pathogens like Listeria monocytogenes can be responsible. Collecting data of these rare situations allows to improve diagnosis.

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Recent studies outline markedly different possible decarbonization pathways for civil aviation by 2050. This paper examines how the key assumptions retained in these scenarios (i.e.

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Toxicity assessment of DMSO extracts of environmental aged beached plastics using human cell lines.

Ecotoxicol Environ Saf

January 2025

Univ. Bordeaux, CNRS, Bordeaux INP, EPOC, UMR 5805, Pessac F-33600, France. Electronic address:

Plastic products contain complex mixtures of chemical compounds that are incorporated into polymers to improve material properties. Besides the intentional chemical additives, other compounds including residual monomers and non-intentionnaly added substances (NIAS) as well as sorbed pollutants are usually also present in aged plastic. Since most of these substances are only loosely bound to the polymer via non-covalently interactions, i.

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Fibroblast plasticity in pulmonary and cardiovascular fibrosis: Mechanistic insights and emerging therapeutic targets.

Arch Med Res

January 2025

Centre for Innovation and eHealth, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania; Institute for Molecular Medicine, University of Southern Denmark, Odense, Denmark; Department of Cardiology, St. Katharinen Hospitals Frechen, Germany.

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Model of drop infiltration into a thin amphiphilic porous medium.

J Colloid Interface Sci

January 2025

UMR1114 EMMAH INRAE-AU, 228, Route de L'Aérodrome, Avignon, F84000, France. Electronic address:

Hypothesis: Water drop infiltration into a thin amphiphilic porous medium is influenced by wettability. Due to the reorganization of amphiphilic matter in contact with water, polar interaction changes the wettability in the bulk porous medium and at the liquid/porous substrate interface. To model out of equilibrium water transfer, we propose a thermodynamics approach derived from Onsager's principle.

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In this study, a novel imidazolium-based ionic liquid (IL) coating was developed for stir bar sorptive extraction (SBSE) using a sol-gel method. The effects of different counterions, conditioning temperatures and polymer compositions were investigated. The stir bar with bis((trifluoromethyl)sulfonyl) amide 1-butyl-3-(3-(triethoxysilyl)propyl)-1H-imidazol-3-ium showed good mechanical and thermal stability with high resistance to water solubilization.

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Deep learning methods have been widely used for various glioma predictions. However, they are usually task-specific, segmentation-dependent and lack of interpretable biomarkers. How to accurately predict the glioma histological grade and molecular subtypes at the same time and provide reliable imaging biomarkers is still challenging.

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Prevalence of Borrelia burgdorferi sensu lato infection in the Czech Republic.

Int J Med Microbiol

January 2025

Global Vaccines, and Anti-infectives Medical Affairs, Pfizer Inc., 1 Portland Street, Cambridge, MA 02139, USA. Electronic address:

Introduction: Lyme borreliosis (LB), an infection caused by Borrelia burgdorferi sensu lato (Bbsl), is the most common tick-borne disease in Europe. To further characterize the LB burden in the Czech Republic, we conducted a seroprevalence study and estimated the incidence of symptomatic Bbsl infections.

Methods: Anti-Bbsl IgM and IgG antibodies were detected in sera collected from the adult population in 2011 -2012 by enzyme-linked immunosorbent assay and immunoblot tests at the National Reference Laboratory.

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