185 results match your criteria: "Fox-Fordyce Disease"

Article Synopsis
  • Fox-Fordyce disease (FFD) is a rare skin condition that leads to itchy, skin-colored bumps, primarily affecting areas with apocrine sweat glands like the armpits and pubic region.
  • This condition can occur as a side effect following laser hair removal treatments, such as those using Alex or Diode lasers.
  • It is important for clinicians to consider FFD as a possible diagnosis when patients experience itchy bumps after receiving hair removal laser treatments.
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Article Synopsis
  • Light-assisted hair removal is increasingly popular, leading to a rise in reported side effects, including ocular and skin complications.
  • A systematic review of literature found 104 relevant studies detailing issues like eye problems, burns, pigment changes, and other skin conditions linked to the procedure.
  • Key recommendations for improving safety include better operator training and a deeper understanding of laser physics to reduce risks associated with these hair removal techniques.*
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Article Synopsis
  • - Fox-Fordyce disease is a chronic skin condition related to the apocrine sweat glands that causes itching and can reduce quality of life.
  • - There is no known cure, and standard treatment usually involves topical corticosteroids, but options for tough cases are limited.
  • - This case study presents a successful treatment of a young patient using botulinum toxin type A injections, showing its effectiveness in a pediatric setting, although it has been reported in adults before.
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Article Synopsis
  • Fox-Fordyce disease (FFD) is a rare chronic inflammation of the apocrine sweat glands, primarily characterized by itchy, raised bumps in areas where these glands are present, such as the underarms and genitals.
  • Research highlights that most affected individuals are young females, with the condition often appearing bilaterally and showing improvement post-menopause.
  • The study suggests that FFD can either be sporadic or familial, may sometimes be asymptomatic, and highlights the need for more clinical trials to explore various treatment options.
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Article Synopsis
  • - Fox-Fordyce disease (FFD) is a rare skin condition mainly affecting postpubertal females, characterized by itchy, skin-colored papules that primarily appear in the armpits but can also occur in other areas like the pubic and umbilical regions.
  • - Diagnosis usually relies on clinical observation since the histological features are often unclear and can mimic other skin conditions, making it challenging to identify.
  • - Dermoscopy is becoming a valuable tool for examining FFD, revealing distinctive features such as brown folliculocentric areas and changes in skin texture, which can help differentiate it from other skin disorders.
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Article Synopsis
  • Fox-Fordyce disease (FFD) is a rare skin condition that affects sweat glands, specifically apocrine glands.
  • A case study describes a 26-year-old woman who developed itchy, raised lesions in her armpits after undergoing two sessions of Diode laser hair removal.
  • Treatment involved applying 0.1% tacrolimus gel to manage the lesions, which did not appear in other areas where she received the laser treatment.
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Rapid remission with calcipotriol betamethasone in refractory Fox-Fordyce disease.

Dermatol Ther

March 2020

Dermatovenerology Department, Celje General and Teaching Hospital, Celje, Slovenia-EU, Institute of Anatomy, Histology, and Embryology, Faculty of Medicine, University of Maribor, Maribor, Slovenia.

Article Synopsis
  • Fox-Fordyce disease (FFD) is a rare skin condition that causes itchy bumps, primarily affecting women in areas with apocrine glands, like underarms and groin.
  • The exact cause of FFD is still not well understood, and finding effective treatments has been difficult.
  • A case study highlights a 26-year-old woman who had little success with previous treatments but found relief using calcipotriol betamethasone, leading to quick improvement of her symptoms.*
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Article Synopsis
  • Fox-Fordyce disease is a rare condition affecting the apocrine glands, primarily seen in young women.
  • It leads to itchy bumps in the armpits that are hard to treat and can significantly impact the patient's quality of life.
  • The report details two cases, confirming the diagnosis through histological examination that revealed a unique feature known as perifollicular xanthomatosis.
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[Axillary and perimamillary Fox-Fordyce disease (apocrine miliaria) in a 19-year-old woman].

Hautarzt

April 2018

Universitäts-Hautklinik Heidelberg, Ruprecht-Karls Universität Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Deutschland.

Article Synopsis
  • Fox-Fordyce disease (FFD) is a rare skin condition mainly seen in young women aged 13 to 35, marked by itching and papules that are skin-colored or light brown/yellowish.
  • The exact cause of FFD is unclear, but hormonal influences and factors like laser hair removal and excessive sweating may worsen the condition.
  • Treatment options for FFD have shown limited effectiveness, making it a difficult disease to manage.
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Article Synopsis
  • Stanisław Ostrowski was the president of prewar Lvov and a Polish Republic figure in Exile, as well as an associate professor and dermatologist focused on dermatopathology.
  • His work mainly consisted of original reports where he provided detailed descriptions of skin conditions, including naevus epitheliomatosus sebaceus and Fox-Fordyce disease, in both Polish and German.
  • The study highlights Ostrowski's significant contributions to dermatopathology, which were influential enough to be referenced in notable handbooks published by Springer Verlag.
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Effective treatment of Fox-Fordyce disease with pulsed dye laser.

Photodermatol Photoimmunol Photomed

September 2016

Department of Pathology, School of Medicine, Göztepe Training and Research Hospital, Istanbul Medeniyet University, Istanbul, Turkey.

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Foxc1 Ablated Mice Are Anhidrotic and Recapitulate Features of Human Miliaria Sweat Retention Disorder.

J Invest Dermatol

January 2017

Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.

Article Synopsis
  • - Sweat glands play a vital role in regulating body temperature, consisting of a secretory portion and a duct that leads to the skin surface, but the genes responsible for their structure and function are still largely unknown.
  • - Research indicates that the transcription factor Foxc1 is essential for proper sweat duct function in mice; when Foxc1 is removed, the glands mature but fail to produce sweat effectively, leading to a condition similar to the human disorder miliaria.
  • - The absence of Foxc1 leads to keratin-based blockages in sweat ducts, causing enlargement of the ducts and skin issues, highlighting Foxc1's key role in regulating the differentiation of sweat duct cells and suggesting a potential animal model for studying sweat retention disorders.
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Inflammatory and glandular skin disease in pregnancy.

Clin Dermatol

May 2017

Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island; Department of Dermatology, Rhode Island Hospital, Providence, Rhode Island.

Article Synopsis
  • * Skin conditions that are Th2-mediated, like atopic dermatitis, may worsen, while Th1-mediated diseases may improve; hormonal changes can also lead to flare-ups in certain gland-related skin diseases.
  • * The review covers several inflammatory and glandular skin diseases during gestation, detailing their causes, symptoms, and treatment options with a focus on safety for both mother and fetus.
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