1,919 results match your criteria: "Fournier Gangrene"
Fournier's Gangrene Mortality Index (FGMI): A New Scoring System for Predicting Fournier's Gangrene Mortality.
Diagnostics (Basel)
December 2024
Department of General Surgery, Faculty of Medicine, Harran University, Şanlıurfa 63300, Turkey.
Objectives: Fournier's gangrene is an aggressive, rapidly progressing, and life-threatening necrotizing fasciitis of the perineal and genital regions. Various scoring systems have been developed for predicting survival and prognosis in Fournier's gangrene. This retrospective study aimed to evaluate the effectiveness of the newly developed Fournier's gangrene mortality index (FGMI) in predicting mortality associated with Fournier's gangrene.
View Article and Find Full Text PDFFournier's gangrene in elderly men: A report of two cases.
Int J Surg Case Rep
December 2024
Nepalese Army Institute of Health Sciences, Kathmandu, Nepal.
Introduction: Fournier's gangrene, a polymicrobial infection affecting the scrotum and perineal area, predominantly affects elderly males, presenting challenges in diagnosis and management. This report examines two cases, with a focus on the rare outcome of bilateral orchidectomy.
Case Presentation: A 69-year-old diabetic male presented with severe penile and scrotal pain, leading to the diagnosis of Fournier's gangrene.
Fournier's gangrene and rectal cancer.
Rev Esp Enferm Dig
December 2024
Cirugía General y del Aparato Digestivo, Hospital Universitario de Toledo, España.
Article Synopsis
Anterolateral Thigh Flap for Abdominal Wall Defect After Debridement for Meleney's With Fournier's Gangrene: A Case Report of a Rare Outcome.
Cureus
November 2024
Institute of General Surgery, Madras Medical College, Chennai, IND.
Article Synopsis
[SGLT2 inhibitors - A novel treatment for congestive heart failure and chronic kidney disease].
Laeknabladid
December 2024
MD, MS. Sahlgrenska University Hospital, Gothenburg, Sweden.
Article Synopsis
- - SGLT2 inhibitors block transporters in the kidneys, which increases sodium and glucose excretion, leading to lower blood sugar levels, improved blood pressure, and weight loss.
- - These medications have shown protective effects for the heart and kidneys, reducing the risk of cardiovascular death, hospitalization due to heart failure, and progression to advanced kidney disease.
- - While SGLT2 inhibitors are generally safe and do not raise the risk of low blood sugar or acute kidney injury, they can lead to rare but serious side effects, like normoglycemic ketoacidosis and Fournier's gangrene, that require medical awareness.
Role of C-Reactive Protein/Lymphocyte and Neutrophil/Lymphocyte Ratios in Predicting Mortality in Patients with Fournier's Gangrene.
J Invest Surg
December 2024
Department of General Surgery, Antalya Education and Research Hospital, University of Health Sciences, Antalya, Turkey.
Article Synopsis
Fournier's Gangrene and Sodium-Glucose Cotransporter 2 Inhibitor Use: A Report of Two Cases.
J Pharm Pract
November 2024
Department of Emergency Medicine, Jesse Brown Veterans Affairs Medical Center, Chicago, IL, USA.
Article Synopsis
[Monkeypox complicated with Fournier's gangrene: A case report].
Rev Med Inst Mex Seguro Soc
July 2024
Instituto Mexicano del Seguro Social, Coordinación de Calidad de Insumos y Laboratorios Especializados. Ciudad de México, México.
Article Synopsis
Management of a complex case of Fournier's gangrene in a female patient with ulcerative colitis.
Tech Coloproctol
November 2024
Department of Surgery, Hospital Sant' Antonio, University of Padova, Padua, Italy.
Imaging of necrotizing fasciitis.
Clin Imaging
December 2024
Department of Radiology, Denver Health, 777 Bannock Street, Denver, CO 80204, United States of America.
Article Synopsis
MR imaging of the penis: What a radiologist needs to know!
Abdom Radiol (NY)
November 2024
Department of Radiology, University of Texas Health, San Antonio, TX, USA.
Article Synopsis
- - MRI is key for checking penile pathologies because it offers high-quality images of soft tissues and can view structures from multiple angles.
- - The review discusses MRI techniques and important anatomy related to these conditions.
- - MRI is not only a supportive tool alongside ultrasound for trauma and infections but is also the main method for evaluating penile prostheses and complicated cases.
Geriatric Nutritional Risk Index in Predicting the Mortality of Fournier's Gangrene: Analysis of 14-Year Statistics of Referral Center.
Arch Acad Emerg Med
September 2024
Clinical Research Development Unit of Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Article Synopsis
National Study of Fournier Gangrene in Spain (2016-2021): Gender/Sex Differences in Mortality and Risks.
Medicina (Kaunas)
September 2024
Department of Clinical Medicine, Miguel Hernández University, 03550 Sant Joan d'Alacant, Spain.
Article Synopsis
Safety of dapagliflozin and empagliflozin in cases with diabetes mellitus or/and heart failure: a retrospective pharmacovigilance study conducted on the eudravigilance database.
Pharmacol Rep
October 2024
Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology - Department of Experimental Medicine, Section of Pharmacology "L. Donatelli", University of Campania "Luigi Vanvitelli", Via Costantinopoli 16, Naples, 80138, Italy.
Article Synopsis
Closure of the initial surgical wound resulting in successful treatment of a pediatric case of Fournier's gangrene: A case report.
Urol Case Rep
November 2024
Department of Urology, Kitasato University School of Medicine, Japan.
Article Synopsis
Comparative analysis of scoring systems for predicting mortality in Fournier gangrene: single center, 15 years experience.
Updates Surg
November 2024
Department of Urology, Faculty of Medicine Hospital, Bezmialem Vakif University, Istanbul, Turkey.
Article Synopsis
- The study evaluated five different scoring systems (FGSI, UFGSI, ACCI, qSOFA, LRINEC) to predict outcomes in patients with Fournier gangrene, analyzing data from 311 patients between 2010 and 2024.
- Univariate and multivariate analyses showed that UFGSI and FGSI were the most effective scoring systems in predicting mortality, with higher values seen in non-survivor patients.
- ROC analysis determined optimal cut-off values for each scoring system, with UFGSI proving to be the most accurate for predicting mortality, achieving 84% sensitivity and 97% specificity at a score ≥12.
Higher Morbidity and Mortality in Females With Fournier Gangrene Compared With Males: Insights From National Inpatient Sample Data.
J Urol
January 2025
Department of Urology, University of California San Francisco, San Francisco, California.
Article Synopsis
- The study compares Fournier gangrene between female and male patients, using data from the National Inpatient Sample from 2016 to 2020, to identify factors related to mortality in both groups.
- It found that a higher percentage of females (7.1%) died from the condition compared to males (5.7%), and that females experienced longer hospital stays and more severe complications.
- Key factors affecting mortality included the time until initial treatment and race, with diabetes found to lower mortality odds for both genders, highlighting the need for timely intervention in female patients.
Revisiting Fournier Gangrene: A Contemporary Epidemiological Perspective vs Perineal Cellulitis.
Urol Pract
January 2025
Department of Urology, University of California San Francisco, San Francisco, California.
Article Synopsis
- A population-based analysis was conducted using National Inpatient Sample data from 2016-2020 to compare risk factors and mortality rates associated with Fournier's gangrene and perineal cellulitis.
- The study identified significant associations between Fournier's gangrene and factors such as Native American race, diabetes, malignancy, and seasonal admissions, while certain racial groups and higher income decreased the likelihood of this condition.
- Increased mortality risks in Fournier's gangrene patients were linked to female gender, Native American ethnicity, and the frequency of medical procedures, highlighting the need for better care access and understanding of the condition for improved patient outcomes.
Platelet-Rich Plasma in Urogynecology: A Case Series.
Cureus
August 2024
Obstetrics and Gynaecology, Hospital Sibu, Sibu, MYS.
Article Synopsis
- Platelet-rich plasma (PRP) is gaining popularity in urogynecology due to its effective results and low side effects.
- This study introduces three new uses of PRP: improving recovery from chronic obstetric anal sphincter injuries, reducing pain in vulvodynia, and promoting healing in recurrent vaginal stenosis after Fournier gangrene.
- The authors also outline patient selection, preparation processes for PRP, and a straightforward protocol to achieve optimal platelet yield without commercial kits.
Fournier's Gangrene Associated With Untreated Crohn's Disease in a Male Patient: A Case Report and Review of the Literature.
Cureus
August 2024
Department of Surgical Oncology, Agios Savvas Anti-Cancer Oncology Hospital of Athens, Athens, GRC.
Article Synopsis
- The patient was admitted with a perianal abscess and cellulitis, and after emergency treatment, he was diagnosed with Fournier's gangrene due to untreated Crohn's disease.
- A comprehensive treatment plan involving surgery and wound therapy was successful, and the patient was referred for further management, highlighting the importance of early diagnosis and multidisciplinary care in managing such rare complications of Crohn's disease.
A needs assessment for simulation-based training in emergency urological skills in Ethiopia.
World J Surg
October 2024
Consultant Urological Surgeon, St James's University Hospital, Leeds, UK.
Article Synopsis
- Urologic emergencies are frequent and often complicated to manage, highlighting the need for effective training methods like simulation-based education (SBE).
- A study in Ethiopia surveyed surgical consultants and residents about their training needs, collecting responses primarily through online platforms, and found strong support for SBE in managing urological emergencies.
- The results indicated a high interest among trainees for a dedicated SBE course, with many participants emphasizing specific topics like acute urinary retention and urologic trauma as critical areas for training.
Case report: is necrotizing fasciitis in a rectal cancer patient after targeted systemic therapy related to the tumor site? - evidence from a hepatocellular carcinoma patient.
Infect Agent Cancer
September 2024
Department of Surgical Oncology, Lanzhou University Second Hospital, Lanzhou, 730030, China.
Article Synopsis
- Necrotizing fasciitis (NF) is a rare but serious infection that causes rapid tissue death in various body areas, particularly in male genital and groin regions, often triggered by multiple types of bacteria.
- While NF can sometimes be linked to tumor sites like rectal or sigmoid colon cancer and issues related to targeted therapy drugs, cases showing NF with these cancers without prior perforation highlight a complex relationship.
- Two patient cases further illustrate the link between targeted therapy and NF, with one developing it after immunotherapy for rectal cancer and another after treatment for hepatocellular carcinoma, suggesting targeted cancer therapies may elevate the risk of developing NF.
Validation of necrotising infection clinical composite endpoint in a retrospective cohort of patients with necrotising soft tissue infections.
Diving Hyperb Med
September 2024
Department of Intensive Care and Hyperbaric Medicine, Alfred Health, Melbourne, Australia.
Article Synopsis
- Rapidly progressive necrotising soft tissue infections (NSTIs) are serious conditions with high risks for patients, and the NICCE offers a useful way to assess treatment effectiveness.
- A study evaluated the NICCE using a cohort of 235 patients with NSTIs, focusing on their severity through the mSOFA score; those with higher scores had worse outcomes.
- The findings suggest that NICCE is better than just using mortality rates, as it identifies patients at risk for complications and could improve the design of clinical trials, especially if it incorporates patient-centered outcomes.
An Uncommon Consequence of Perforated Acute Appendicitis in Elderly Patients: Fournier's Gangrene.
Cureus
August 2024
General and Colorectal Surgery, Glan Clwyd Hospital, Rhyl, GBR.
Article Synopsis
- Untreated acute appendicitis can lead to serious complications like necrotizing fasciitis, especially in older patients.
- A 77-year-old man developed Fournier's gangrene due to a perforated appendix, despite not showing typical symptoms initially.
- This case emphasizes the importance of recognizing atypical symptoms in elderly patients and the need for prompt surgical treatment to prevent severe infections.