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Ecotoxicol Environ Saf
March 2025
Foshan Fetal Medicine Research Institute, Foshan Maternity and Children's Healthcare Hospital Affiliated to Guangdong Medical University, Foshan, China; Department of Obstetrics, Foshan Maternity and Children's Healthcare Hospital Affiliated to Guangdong Medical University, Foshan, Guangdong, China. Electronic address:
Background: Tributyltin (TBT), a prevalent environmental antiseptic, contaminates seafood, fish, and drinking water, posing health risks. While TBT's hepatic toxicity is well-known, its sex-specific effects on liver function remain poorly understood.
Methods: To address this gap, a comprehensive analysis was conducted utilizing the Toxicant Exposures and Responses by Genomic and Epigenomic Regulators of Transcription (TaRGET) dataset.