Discordance in Recommendation Between Next-Generation Sequencing Test Reports and Molecular Tumor Boards in India.

Purpose: Accurate understanding of the genomic and transcriptomic data provided by next-generation sequencing (NGS) is essential for the effective utilization of precision oncology. Molecular tumor boards (MTBs) aim to translate the complex data in NGS reports into effective clinical interventions. Often, MTB treatment recommendations differ from those in the NGS reports.

A Study to Analyze Impact of Treatment Couch and Immobilization Devices on Surface Dose for Megavoltage Photon Beams.

Purpose/objective: The purpose of this study is to investigate the effect of treatment couch and immobilization devices on surface dose for megavoltage photon beams.

Material/methods: Percentage surface dose (PSD) measurement was carried out in Elekta Synergy™ Linear accelerator using PTW Markus® Parallel plate ionization chamber of volume 0.05cm3 with water equivalent RW3 Slab phantom (PTW, Germany).

Practical Clinical Consensus Guidelines for the Management of Cancer Associated Anemia in Low- and Middle-Income Countries.

Purvish M. ParikhCancer-associated anemia (CAA) remains a major unmet need that compromises overall survival (OS) and quality of life (QoL). Currently, available guidelines do not take into consideration the unique challenges in low- and middle-income countries (LMIC).

Analysis of Rapid arc-based Radiation Therapy on Dosimetric Parameters in Cervical Cancer Patients with and without Bone Marrow Sparing.

Background: The standard treatment for cervical cancer is chemoradiation therapy. Pelvic radiation is associated with higher dose to bone marrow (BM) causing interrupted treatment due to haematologic toxicity with inferior outcomes. This study aims to evaluate rapid arc technique in sparing pelvic BM and dosimetric parameters for pelvis V5GY, V10GY, V20GY, V30GY, and V40GY dose.

Dosimetric Importance of Implementing Jaw Tracking Technique in Radiotherapy Treatment Plan Execution.

Objective: To study the dosimetric importance of Jaw tracking technique in reducing the doses to organs at risk (OAR) while achieving the optimal dose coverage for the target.

Methods: We retrospectively selected ten Glioblastoma cases and for each patient, two plans were created namely Static Jaw Technique Dynamic Intensity Modulated Radiotherapy plan and Jaw Tracking Technique D-IMRT plan with 6 MV for Varian Truebeam™ STx machine using Eclipse Treatment planning system. Both plans were analyzed and compared based on various dosimetric parameters for Planning Target Volume (PTV) and OARs.

Dosimetric Importance of the Implementation of Daily Image Guidance in Radiotherapy Practice.

Background: The purpose of this study is to show the dosimetric importance of using daily image guidance in radiotherapy treatment.

Methods: A sample of 30 patients with various head and neck cancers were retrospectively selected for the studies. The prescribed dose, 66 Gy/33 fractions was used for all patients who received 7 to 9 beams, 6 MV Intensity Modulated Radiation Therapy (IMRT) plan delivered by Varian Truebeam STx.

Evaluation of Dosimetric Effect of Millennium and High Definition Multi Leaf Collimator Using 6 MV Photon Beams.

Purpose: The present study aims to compare different dosimetric parameters from field sizes defined by secondary and tertiary collimators. A comparison has been drawn between two types of Multi Leaf Collimator (MLC) designs.

Materials And Methods: The measurements were obtained using Millennium MLC (Mi-MLC) from Varian Unique™ linear accelerator (LINAC-1) and compared with measurements from Varian Truebeam™ linear accelerator (LINAC-2) using High Definition MLC (HD-MLC).

Adaptations and Safety Modifications to Perform Safe Minimal Access Surgery (MIS: Laparoscopy and Robotic) During the COVID-19 Pandemic: Practice Modifications Expert Panel Consensus Guidelines from Academia of Minimal Access Surgical Oncology (AMASO).

The pandemic of COVID-19 across the globe triggered national lockdowns hampering normal working for all the essential services including healthcare. In order to reduce transmission and safety of patients and healthcare workers, the elective surgeries have been differed. The visits to the hospitals for follow-ups and consultations received temporary halt.

IMPACT OF THREE DIFFERENT MATCHING METHODS ON PATIENT SET-UP ERROR IN X-RAY VOLUMETRIC IMAGING FOR HEAD AND NECK CANCER.

Impact of three different matching methods for delivery of Volumetric Modulated Arc Therapy (VMAT) in Cone-beam computed tomography (CBCT) on patient set-up error. As per institutional imaging protocol, 300 CBCT scans of 20 VMAT head and neck cancer patients treated with 60 Gy/30 fractions were chosen for the present study. Approved CT images of the plan were registered as a reference with the CBCT images on board.

Dosimetric impact of statistical uncertainty on Monte Carlo dose calculation algorithm in volumetric modulated arc therapy using Monaco TPS for three different clinical cases.

Aim: To study the dosimetric impact of statistical uncertainty (SU) per plan on Monte Carlo (MC) calculation in Monaco™ treatment planning system (TPS) during volumetric modulated arc therapy (VMAT) for three different clinical cases.

Background: During MC calculation SU is an important factor to decide dose calculation accuracy and calculation time. It is necessary to evaluate optimal acceptance of SU for quality plan with reduced calculation time.

Study to Compare the Effect of Different Registration Methods on Patient Setup Uncertainties in Cone-beam Computed Tomography during Volumetric Modulated Arc Therapy for Breast Cancer Patients.

Purpose: This study compared three different methods used in registering cone-beam computed tomography (CBCT) image set with planning CT image set for determining patient setup uncertainties during volumetric modulated arc therapy (VMAT) for breast cancer patients.

Materials And Methods: Seven breast cancer patients treated with 50 Gy in 25 fractions using VMAT technique were chosen for this study. A total of 105 CBCT scans were acquired by image guidance protocol for patient setup verification.

Validation of a Software Upgrade in a Monte Carlo Treatment Planning System by Comparison of Plans in Different Versions.

Purpose: Validation of a new software version of a Monte Carlo treatment planning system through comparing plans generated by two software versions in volumetric-modulated arc therapy (VMAT) for lung cancer.

Materials And Methods: Three patients who were treated with 60 Gy/30 fractions in Elekta Synergy™ linear accelerator by VMAT technique with 2% statistical uncertainty (SU) were chosen for the study. Multiple VMAT plans were generated using two different software versions of Monaco treatment planning system TPS (V5.