[A case of anti-ganglioside antibody-positive Guillain-Barré syndrome with asymmetrical muscle weakness throughout the course of the disease].

A 56-year-old woman who presented with left drop foot and low back pain a week after the onset of diarrhea. Neurological symptoms progressed for a week and gradually improved thereafter. No weakness was observed in upper limbs and clearly asymmetrical muscle weakness was observed in left lower limbs during the course of the disease.

Posture-induced compressive peroneal neuropathy during harvesting season: A case series.

Posture-induced compressive peroneal neuropathy usually occurs after maintaining certain positions, such as prolonged squatting or habitual leg crossing. Peroneal neuropathy mainly presents with unilateral foot drop and variable sensory deficit. In this article, a case series of unilateral/bilateral peroneal nerve palsy secondary to prolonged squatting during peanut harvesting was reported.

Treatment of Terminal Syrinx With a Syringo-Subarachnoid Shunt and the Novel Use of a Titanium Knot Fastener: A Case Report.

A syrinx involves cystic dilation of the central canal of the spinal cord due to the accumulation of cerebrospinal fluid and often results in a neurological deficit. While treatment options vary, surgical management is often utilized and requires an open durotomy. A 70-year-old female presented with one year of progressive low back pain with associated leg numbness, urinary incontinence, bilateral foot drop, and imbalance resulting in multiple falls.

Acquisition, Retention, and Transfer Effects of Landing Training to Increase Foot Progression Angle During Bilateral Drop Landings.

Foot position during landing directly influences knee mechanics. Thus, the purpose of this study was to determine success in practicing, repeating, and transferring a desired foot progression angle (FPA) during landing, as well as changes in knee mechanics. Twenty females were randomly assigned to a control or verbal instruction group.

A patient with a PTPN11 gene variant complicated with Chiari I malformation and syringomyelia and a review of literatures.

Background: According to previous literature reports, PTPN11 gene variants account for approximately 50% of Noonan syndrome (NS) cases and 85% of Leopard syndrome (LS) cases. Several patients who were diagnosed with NS or LS complicated with Chiari I malformation (CIM) and/or syringomyelia have been reported to have a PTPN11 variant. However, it is not always clear whether the association between CIM and/or syringomyelia and PTPN11 variants is real or random.

Delayed percutaneous intradiscal hydrogel herniation causing neurological injury after minor trauma: illustrative case.

Background: Percutaneous intradiscal hydrogel injection has been used to treat low-back pain (LBP) due to degenerative disc disease with or without mild radicular pain. Complications from these procedures are underreported. In this case lesson, the authors present a rare case of a patient with herniated intradiscal hydrogel following a minor trauma leading to neurological injury.

The effects of combined exercises, short foot exercises, and short foot exercises with isometric hip abduction on navicular drop, static parameters, and postural sway in women with flat foot: A randomized trial.

Background: Recent research has found that strengthening hip joint stability can considerably affect foot mechanics. The purpose of this study was to determine the effect of short foot exercises (SFEs), combined exercises (CEs), and SFEs with isometric hip abduction (IHA) on navicular drop (ND), static parameters (SP), and postural sway in women with flat foot (FF).

Methods: This study recruited 45 women with flexible FF.

Ultrasound as a Complementary Tool to Electrodiagnostics in the Evaluation of Compressive Neuropathy of the Common Fibular Nerve.

Background: Compressive neuropathy of the common fibular nerve (CFN) is increasingly recognized as an etiology for foot drop and falls. Electrodiagnostic (EDX) studies are widely used to evaluate this condition, but such tests are invasive and costly. As with carpal and cubital tunnel syndromes, there may be patients with characteristic symptoms of CFN compressive neuropathy but normal EDX studies in which ultrasound may aid in decision-making.

Neglected, Perineural, Chronic, Extra-articular, Lateral, Gangliomatous Synovial Knee Cyst With Peroneal Neuropathy: A Case Report.

Lateral knee cysts are relatively common synovial swelling. They are commonly benign swelling due to synovial fluid herniation from the joint. They are usually asymptomatic and in most cases are so small that only magnetic resonance imaging (MRI) can confirm the diagnosis.

Simultaneous reconstruction of tibial osteomyelitis-complicated soft tissue defects using free flap transplantation in conjunction with the masquelet technique: a retrospective study.

Objective: To investigate the clinical effect of anterolateral femoral free flap combined with Masquelet technique in the treatment of tibial osteomyelitis with wound surface.

Methods: A retrospective study was conducted to analyze the clinical data of 25 patients with tibial osteomyelitis combined with defected wounds in Xijing Hospital of Fourth Military Medical University from Jun 2017 to Oct 2021. After one-stage treatment with free flap combined with Masquelet technique, the infection index, lower extremity function score (LEFS), and Mazur ankle function score were compared before bone defect repair and at the last follow-up.

Autosomal recessive -related disorder: comprehensive analysis of phenotypic variability and genetic mutations.

A newly identified subtype of hereditary axonal motor neuropathy, characterized by early proximal limb involvement, has been discovered in a cohort of 34 individuals with biallelic variants in von Willebrand factor A domain-containing 1 (). This study further delineates the disease characteristics in a cohort of 20 individuals diagnosed through genome or exome sequencing, incorporating neurophysiological, laboratory and imaging data, along with data from previously reported cases across three different studies. Newly reported clinical features include hypermobility/hyperlaxity, axial weakness, dysmorphic signs, asymmetric presentation, dystonic features and, notably, upper motor neuron signs.

Severe subacute onset sensorimotor polyneuropathy associated with brentuximab vedotin treatment for refractory classical Hodgkin's lymphoma.

A man in his 30s with a history of refractory classical Hodgkin's lymphoma presented with subacute onset asymmetric sensory disturbance, and severe weakness affecting his right more than left hand. Symptom onset was 18 weeks after commencing brentuximab vedotin (BV) treatment, an anti-CD30 antibody drug-conjugate for relapsed/refractory classical Hodgkin's lymphoma. Symptoms progressed to his lower limbs with distal sensory loss, gait imbalance, bilateral foot drop and mild proximal leg weakness.

Evaluation of a time-varying cut-off frequency low-pass filter for assessing knee joint moments and ACL injury risk.

Conventional low-pass filtering of 3D motion capture signals prior to estimating knee joint moments and ACL injury risk has known limitations. This study aimed to evaluate the fractional Fourier filter (FrFF), which employs a time-varying cut-off frequency, for assessing peak knee moments during common ACL injury risk screening tasks. Ground reaction force and motion data were collected from 23 team sport athletes performing 45° unanticipated sidesteps and drop jumps.

Comparative efficacy and safety of Chinese patent medicines as an adjunctive therapy for diabetic peripheral neuropathy: systematic review and network meta-analysis of randomized controlled trials.

Context: Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes mellitus. Chinese patent medicines (CPMs) are widely used in clinical practice to treat DPN.

Objective: This study aims to summarize the latest evidence on the harms and benefits of CPMs as adjunctive therapy for DPN.