Reciprocating Torsional Fatigue and Mechanical Tests of Thermal-Treated Nickel Titanium Instruments.

Introduction: This study aimed to evaluate the mechanical properties of Reciproc, Reciproc Blue, One RECI, and R-Motion, specifically focusing on their flexibility and buckling resistance and to assess their torsional fatigue behavior under 2 different reciprocation angles (150°/30° or 70°/30°).

Methods: A total of 160 instruments (40 per brand) were tested. Flexion and buckling tests were conducted using a Universal testing machine (DL 200 MF).

Mercury Levels in the Worldwide Farmed Fish: A Systematic Review.

Aquaculture, specifically farmed fish, contributes to global aquatic fish stuff production. The present study systematically reviewed mercury levels in farmed fish. One hundred two scientific articles were found in four databases.

Metabolic acidosis with elevated anion gap and euglycemic ketoacidosis in pregnant and postpartum women with severe Covid-19.

Background/objectives: Pregnant and postpartum women have a higher risk for developing severe Covid-19 and other clinical and obstetric complications. This study aims to evaluate the frequency of metabolic acidosis with elevated anion gap and describe a case series of euglycemic ketoacidosis (EKA) in pregnant and postpartum women with severe confirmed or suspected Covid-19.

Materials And Methods: Observational retrospective study carried in a reference intensive care unit from May 2020 to June 2022.

Cell death by apoptosis induced by (Schott) Mez essential oil in different cancer cell lines.

Cancer is the second leading cause of death in the world. Plants from genus have been studied for their biological activities. Here we evaluated the antitumor activity of essential oil in several cancer cell lines and its phytochemical composition.

Effects of a pre-enlargement on fracture incidence of reused reciprocating instruments: A clinical study.

This study assessed the impact of pre-enlarging the root canal using a size 25 K-file on the fracture incidence of three reciprocating instruments after multiple uses. After a glide path performed with a size 15 K-file, the instruments (Reciproc R25, Reciproc Blue R25, and WaveOne Gold Primary) were initially used in 936 root canals. Then, for the second and third uses (933 and 927, respectively), a pre-enlargement using a size 25 K-file at the working length was done.

A systematic review and meta-analysis of users versus non-users: unveiling the influence of proton pump inhibitors on capecitabine efficacy in colorectal cancer.

Introduction: Colorectal cancer is the second leading cause of cancer-related deaths worldwide. The impact of proton pump inhibitors (PPIs) on patients taking capecitabine, an oral fluoropyrimidine, remains uncertain, despite their use by 20 to 55% of cancer patients. We investigated how PPIs affect the effectiveness of capecitabine in treating colorectal cancer.

Immune Profile and MRI-Detected Cardiac Fibrosis and Edema in Hypertensive and Non-Hypertensive Patients with COVID-19.

Cardiac involvement in 2019 coronavirus disease (COVID-19) survivors has been reported frequently. An exacerbated immune response may be the main mechanism of myocardial injury and late cardiac sequelae in this population. We investigated the immune profile in hypertensive and non-hypertensive patients with COVID-19 who developed late cardiac fibrosis and edema, as detected by magnetic resonance imaging (MRI).

Disordered Eating Behaviors and Weight Regain in Post-Bariatric Patients.

Background/objective: Weight regain has serious health consequences after bariatric surgery, and disordered eating behaviors (EBs) may be involved in it. We compared disordered EB symptoms in post-bariatric patients according to low vs. high ratio of weight regain (RWR) and investigated associations between disordered EB symptoms with weight regain and time since surgery.

Metabolic and Regulatory Pathways Involved in the Anticancer Activity of Perillyl Alcohol: A Scoping Review of In Vitro Studies.

Background/objectives: Perillyl alcohol (POH), a plant-derived compound, has demonstrated anti-tumor activity across various human cancers. Understanding the regulatory pathways through which POH exerts its effects is crucial for identifying new therapeutic opportunities and exploring potential drug repositioning strategies. Therefore, this scoping review aims to provide a comprehensive overview of the metabolic and regulatory pathways involved in the anticancer effects of POH, based on in vitro evidence.

(Re)building the nervous system: A review of neuron-glia interactions from development to disease.

Neuron-glia interactions are fundamental to the development and function of the nervous system. During development, glia, including astrocytes, microglia, and oligodendrocytes, influence neuronal differentiation and migration, synapse formation and refinement, and myelination. In the mature brain, glia are crucial for maintaining neural homeostasis, modulating synaptic activity, and supporting metabolic functions.

Pumpkin seed protein as a carrier for Astaxanthin: Molecular characterization of interactions and implications for stability.

This study investigated pumpkin seed protein (PSP) as a carrier for astaxanthin (AST). Interaction mechanisms revealed through fluorescence spectroscopy and molecular docking, showed that hydrogen bonds and Van der Waals forces form the PSP-AST complex. AST binding altered PSP's secondary structure, increasing α-helix (7.

Letter to the editor in response to "Microbial colonization in the partially exposed nonabsorbable membrane during alveolar ridge preservation" (Braz et al., clinical oral Investigations, https://doi.org/10.1007/s00784-024-05763-7.).

Objective: This letter addresses the recent study by Braz et al. published in Clinical Oral Investigations in 2024 ( https://doi.org/10.

Cinnamon powder intake enhances the effect of caloric restriction on white adipose tissue in male rats.

Caloric Restriction (CR) and cinnamon promote several benefits, including the modulation of lipid metabolism and body fat mass. We hypothesize that cinnamon may act as a mimetic of restriction or enhance the effects of caloric restriction on adipose tissue. Adult male Wistar rats were divided into Control (CT, n = 8) and Cinnamon (CIN, n = 7), with free access to standard chow; Calorie Restriction (CR, n = 8) and Calorie Restriction with Cinnamon (CIN-CR, n = 7), subjected to a 30% reduction in food intake compared to the average consumption of CT rats.

The correlation between abnormal Krüger strict morphology and the sperm DNA fragmentation index.

Objective: This study aims to investigate whether alterations in sperm DNA fragmentation rates are more frequent when Krüger strict morphology is ≥4% (normal).

Methods: The retrospective study included 132 participants from March 2020 to November 2021. Participants were divided into two groups based on the inclusion criteria: normal and abnormal Krüger strict morphology, with a mean age of 40 years.

Magnetic Resonance Imaging Features for Distinguishing High-Grade From Low-Grade Soft Tissue Sarcoma: A Systematic Review and Meta-Analysis.

Soft tissue sarcomas are malignant tumors characterized by heterogeneity and are associated with a high mortality rate. Histopathological grading is considered a pivotal factor in prognostication and treatment planning. While core needle biopsy exhibits high accuracy in determining tumor histology, it fails in some cases, potentially misclassifying high-grade tumors as low-grade.

Enhancing the functionality of yogurt: Impact of exotic fruit pulps addition on probiotic viability and metabolites during processing and storage.

The effect of exotic fruit pulp (araçá, cagaita, cambuci, grumixama, blueberry, and uvaia) on probiotic viability during storage and after gastrointestinal tract (GIT) simulation, in vitro biological activity, total phenolics (TPC) and flavonoids content, and the production of metabolic products of microbial in probiotic yogurt were investigated. During the storage period (28 days), probiotic strain populations remained high (above 6 log CFU/g), while after the GTI simulation, L. acidophilus and B.

Regulatory issues related to the use of sodium hypochlorite solutions in endodontics.

Aim: To assess the regulation of sodium hypochlorite (NaOCl) solutions for endodontic usage in some of the world's main dental markets, in view of the European Union's recent move to classify antimicrobial root canal irrigants as high-risk devices under their Medical Device Regulation (MDR).

Methodology: The authors consulted legal texts available online and communicated with local health authorities wherever necessary to assess into which medical device category NaOCl solutions intended for endodontic application were subsumed. Furthermore, it was investigated whether there were sources outside the dental market to obtain NaOCl solutions for root canal treatments.

Serum microRNA 143 and 223 Gene Expression Profiles as Potential Biomarkers in Individuals with Hepatitis and COVID-19.

MicroRNAs (miRNAs) can act as biomarkers and descriptors of the association between infections and other diseases, such as hepatitis and COVID-19. This study aims to investigate the role of miRNA serum expression according to laboratory data concerning hepatitis and COVID-19. Seventy individuals recruited in Southern and Southeastern Brazil donated serum samples and were divided into four groups: (i) 20 negative subjects, (ii) 20 presenting hepatitis, (iii) 19 with COVID-19 and (iv) 11 with hepatitis and COVID-19.

Multifunctional Metasurface with PIN Diode Application Featuring Absorption, Polarization Conversion, and Transmission Functions.

The objective of this paper is to explore the potential of integrating three distinct functionalities into a thin, single-layer metasurface. Specifically, the study introduces a metasurface design that combines absorption, polarization conversion, and transmission capabilities. The proposed structure consists of a double square loop disposed on a dielectric substrate, which is covered by a superstrate.

Time of Energy Intake: Association with Weight Status, Diet Quality, and Sociodemographic Characteristics in Brazil.

This study aimed to estimate the association of time of energy intake with weight status, diet quality, and sociodemographic characteristics in Brazil. This cross-sectional study used data from a nationally representative survey with 44.744 individuals (≥10 years old).

Effects of intradialytic bicycle ergometer exercise on transcription factors NF-ĸB and Nrf2 in patients with chronic kidney disease: A randomized crossover clinical trial.

Purpose: To evaluate the effects of an intradialytic aerobic exercise training program on the expression of transcription factors nuclear factor κappa B (NF-κB) and nuclear factor erythroid 2-related factor 2 (Nrf2), related to inflammatory and antioxidant pathways, respectively, in patients with chronic kidney disease (CKD) on hemodialysis.

Methods: This was a longitudinal, randomized clinical trial with a washout period and crossover performed with 33 patients randomized into two groups: Exercise (individualized intradialytic aerobic exercise on an adapted stationary exercise bike) three times per week for three months and control (without exercise). After the washout period (1 month), the exercise group became the control, and the other group performed the exercises for another three months.