13,401 results match your criteria: "Fla; Jackson Memorial Hospital[Affiliation]"

Cough and itch: Common mechanisms of irritation in the throat and skin.

J Allergy Clin Immunol

January 2025

Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, Miami Itch Center, University of Miami Miller School of Medicine, Miami, Fla. Electronic address:

Article Synopsis
  • Cough and itch are essential protective responses, helping to expel irritants from the body, but can lead to chronic conditions that diminish quality of life.
  • The article explores the mechanisms behind chronic cough and chronic itch, highlighting their similarities and differences to develop new treatment options.
  • A comprehensive review of literature revealed shared triggers, nervous system processing, and immune responses for both cough and itch, suggesting that therapies targeting these neuroimmune pathways could benefit both conditions.
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Carbon nano dots (CNDs) has received a lot of attention in recent years due to their potential use in various kinds of applications. Many conventional chemical methods have been used to synthesis CNDs, but these processes have several drawbacks, such as hazardous by products, harsh chemicals, and high costs. To overcome these issues, green chemistry has an importance in the development of CNDs.

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Statement Of Problem: The maxillary lateral incisor is often congenitally missing in patients with a cleft palate. The congenital cleft presents the practitioner with challenges including quantity and quality of bone, a surgically managed cleft correction, and limited clinical space.

Purpose: The purpose of this investigation was to calculate the 5-year success and survival rate of narrow-diameter implants used to restore a missing lateral incisor in patients with a cleft palate.

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Identification and mapping of late blight resistance QTLs in the wild tomato accession PI 224710 ().

Mol Breed

October 2024

Department of Plant Science and the Intercollege Graduate Degree Program in Plant Biology, The Pennsylvania State University, University Park, PA 16802 USA.

Unlabelled: Late blight (LB), caused by oomycete , is one of the most destructive diseases of the cultivated tomato, . Since new and aggressive clonal lineages of , many of which overcoming formerly effective fungicides or host resistance genes, have continued to emerge, it is crucial to identify, characterize, and utilize new sources of host resistance in tomato breeding. A recent screening of tomato germplasm identified accession PI 224710 with very strong resistance to several current clonal lineages.

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Article Synopsis
  • Common variable immunodeficiency (CVID) is a prevalent immunodeficiency condition, with only about 30% of cases having a defined genetic cause, highlighting a gap in understanding mortality risk factors.
  • Researchers conducted a study on 21 patients in Córdoba, Argentina, examining their clinical data and immune cell types to develop a mortality predictive score.
  • Key findings revealed that lower counts of CD4 T cells, natural killer (NK) cells, and memory switched B cells were significantly associated with reduced survival rates, leading to the proposal of a scoring system based on these immune cell types to estimate mortality risk in CVID patients.
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Purpose: College students are at an increased risk for trauma exposure (TE), as well as weight gain and subsequent obesity. Notably, existing research has demonstrated that TE is associated with subsequent obesity. However, there is a dearth of literature looking at this relationship in college students who are at increased risk.

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Xenobiotic response element (XRE) to flavone was the cis- regulatory elements that mediates the induction of the allelochemical-metabolizing CYP321A1 gene from Helicoverpa zea. However, it was unknown whether the XRE-Fla element existed in other species. Recently we have identified and cloned the CYP321A1 gene with promoter region in a related species, Helicoverpa armigera.

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Article Synopsis
  • - Parkinson's disease can lead to gastrointestinal issues like constipation, and a Mediterranean diet (MediDiet) may help manage these symptoms.
  • - In a study, participants with Parkinson's were either given standard care for constipation or a MediDiet alongside standard care for 8 weeks; both groups saw reduced constipation scores but no significant differences between them.
  • - The MediDiet group consumed more dietary fiber and showed a trend towards lower intestinal inflammation compared to the control group, suggesting it offers extra benefits beyond symptom relief.
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Pediatric Desmoid Tumor of the Head and Neck: A Systematic Review and Modified Framework for Management by Age Group.

Plast Reconstr Surg Glob Open

September 2024

Division of Pediatric Plastic and Reconstructive Surgery, Department of Pediatric Surgery, AdventHealth for Children, Orlando, Fla.

Article Synopsis
  • Pediatric head and neck desmoid tumors (DTs) can significantly disrupt normal development, necessitating clear management strategies.
  • A systematic review across various databases analyzed 44 studies involving 121 patients, focusing on tumor location, treatment outcomes, and age-related differences in management.
  • The findings highlight that DTs commonly occur in younger patients, are often treated with local resection leading to positive margins, and emphasize the need for more rigorous follow-up to improve treatment practices and reduce recurrence rates.
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  • * A case report describes a 48-year-old male with eye keratitis caused by V. vermiformis, identified through culture and molecular techniques after experiencing trauma to his eye.
  • * Treatment with chlorhexidine led to clinical improvement within 72 hours and complete resolution in 5 weeks, highlighting the importance of recognizing V. vermiformis as a potential cause of corneal infections, alongside the more known Acanthamoeba.
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Background: Seafood allergy (SA), including allergy to shellfish (crustacean and mollusks) and fish, is among the 4 most common food allergies causing anaphylaxis, but there are limited data showing SA clinical management in different countries.

Objective: We sought to characterize a large cohort of patients with fish and shellfish allergy and to facilitate standardization of future care for this increasingly common allergic disease.

Methods: We performed a retrospective, observational, noninterventional study from 945 patients from 2015 to 2019 in 7 hospitals in the United States and the United Kingdom to evaluate SA.

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Background: Tiny arteriovenous (AV) shunts of 10-150 µm (0.01-0.15 mm) are documented in the hands and feet.

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Recent reports of fatal meningoencephalitis from Kerala, South India, are creating ripples among medical and health administrations. Free-living amoebae (FLA) have been attributed to these infections. Despite their free-living nature, these amoebae have been recognized as potential opportunistic organisms that occasionally cause infections in immunocompetent and immunocompromised individuals.

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Biofilms are a critical factor for food safety, causing important economic losses. Among the novel strategies for controlling biofilms, essential oils (EOs) can represent an environmentally friendly approach, able to act both on early and mature stages of biofilm formation. This review reports the anti-biofilm mechanisms of action of EOs against five pathogenic bacterial species known for their biofilm-forming ability.

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Background: ChatGPT, launched in 2022 and updated to Generative Pre-trained Transformer 4 (GPT-4) in 2023, is a large language model trained on extensive data, including medical information. This study compares ChatGPT's performance on Plastic Surgery In-Service Examinations with medical residents nationally as well as its earlier version, ChatGPT-3.5.

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Article Synopsis
  • * Introducing 4-fluoroaniline (4-FLA) as an additive helps regulate the growth and distribution of PbI crystals, improving their uniform dispersion and reducing related defects.
  • * The modified perovskite films show enhanced hydrophobicity and achieved a PCE of 21.63% with a voltage of 1.16V, offering a promising strategy for creating more efficient and stable PSCs.
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The #HOPE4LIVER Single-Arm Pivotal Trial for Histotripsy of Primary and Metastatic Liver Tumors.

Radiology

September 2024

From the Department of Radiology, University of Michigan Medicine, Ann Arbor, Mich (M.M.L., N.D.P., C.C.); Institut für Röntgendiagnostik und Nuklearmedizin, Städtisches Klinikum Braunschweig, Braunschweig, Germany (P.W., M.P.); Klinik für Radiologie und Nuklearmedizin, Universitätsklinikum Magdeburg, Magdeburg, Germany (M.P., M.T.); Department of Radiology, Vall d'Hebrón University Hospital, Barcelona, Spain (X.S.C.); Department of Radiology, Medical College of Wisconsin, Milwaukee, Wis (S.B.W.); Department of Radiology, Tampa General Hospital, Tampa, Fla (C.D.); Department of Interventional Radiology, University of Chicago Pritzker School of Medicine, Chicago, Ill (O.A.); Departments of Biomedical Engineering, Radiology, and Neurosurgery, University of Michigan, Ann Arbor, Mich (Z.X.); Department of Radiology, University of Kansas Medical Center, Kansas City, Kan (Z.C.); Department of Interventional Radiology, Baptist Hospital of Miami, Miami, Fla (G.N.); Department of Biomedical Science, Humanitas University & Humanitas Clinical and Research Hospital IRCCS, Rozzano, Italy (G.T., L.S.); Department of Radiology, Freeman Hospital, Newcastle, United Kingdom (P.L.); Department of Diagnostic and Interventional Radiology, Leeds Teaching Hospital and Trust, West Yorkshire, United Kingdom (T.M.W.); and Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI 53792 (T.J.Z.).

Background Histotripsy is a nonthermal, nonionizing, noninvasive, focused US technique that relies on cavitation for mechanical tissue breakdown at the focal point. Preclinical data have shown its safety and technical success in the ablation of liver tumors. Purpose To evaluate the safety and technical success of histotripsy in destroying primary or metastatic liver tumors.

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MRI Predicts Residual Disease and Outcomes in Watch-and-Wait Patients with Rectal Cancer.

Radiology

September 2024

From the Departments of Surgery, Colorectal Service (H.W., D.M.O., H.M.T., F.S.V., J.B.Y., J.B., M.R.M., J.G.A.), Epidemiology and Biostatistics (S.T.L., L.X.Q.), and Radiology (J.M., M.J.G.), Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065; Department of Radiology, University of Rochester Medical Center, Rochester, NY (D.A.D.); Department of Radiology, University of South Florida, Tampa, Fla (R.K.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology, Oregon Health and Science University, Portland, Ore (E.K.); Department of Radiology, Cleveland Clinic, Cleveland, Ohio (J.C.V.); Department of Radiology, John Muir Health, Walnut Creek, Calif (S.G.); Department of Radiology, University of Virginia, Charlottesville, Va (A.K.); Department of Radiology, University of Washington, Seattle, Wash (M.J.); Department of Radiology, St Joseph Hospital Orange County, Orange, Calif (K.O., D.V.); Department of Radiology, University of California San Francisco, San Francisco, Calif (T.A.H.); Department of Radiology, University of California Irvine, Irvine, Calif (S.L.); Department of Radiology, University of Michigan, Ann Arbor, Mich (A.P.W.); and Department of Radiology, University of Colorado Anschutz Medical Campus, Aurora, Colo (N.M.).

Background MRI plays a crucial role in restaging locally advanced rectal cancer treated with total neoadjuvant therapy (TNT); however, prospective studies have not evaluated its ability to accurately select patients for nonoperative management. Purpose To evaluate the ability of restaging MRI to predict oncologic outcomes and identify imaging features associated with residual disease (RD) after TNT. Materials and Methods This was a secondary analysis of the Organ Preservation in Rectal Adenocarcinoma (OPRA) trial, which randomized participants from April 2014 to March 2020 with stages II or III rectal adenocarcinoma to undergo either induction or consolidation TNT.

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Expressing plant metabolic pathways in microbial platforms is an efficient, cost-effective solution for producing many desired plant compounds. As eukaryotic organisms, yeasts are often the preferred platform. However, expression of plant enzymes in a yeast frequently leads to failure because the enzymes are poorly adapted to the foreign yeast cellular environment.

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Frontal EEG alpha asymmetry predicts foreign language anxiety while speaking a foreign language.

Behav Brain Res

October 2024

Section of Child & Adolescent Psychiatry, Department of Psychiatry, Chang Gung Memorial Hospital at Taoyuan, No. 123, Dinghu Rd., Guishan Dist., Taoyuan City 333, Taiwan, ROC; School of Medicine, Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan Tao, Yuan 333, Taiwan, ROC. Electronic address:

Article Synopsis
  • Engaging in dialogue requires individuals to effectively send and receive messages while managing emotions, which can be more challenging when using a foreign language due to anxiety.
  • Research using EEG studies indicates that anxiety can be measured through frontal alpha asymmetry (FAA) in the brain.
  • The findings suggest that FAA is a significant predictor of anxiety levels during the speaking section of a second language anxiety scale, highlighting potential methods to enhance communication in foreign language interactions.
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Intraprocedural Diffusion-weighted Imaging for Predicting Ablation Zone during MRI-guided Focused Ultrasound of Prostate Cancer.

Radiol Imaging Cancer

September 2024

From the Departments of Radiology (R.R.B., Y.C., R.L.B., M.R., P.G.) and Urology (G.S.), Stanford University School of Medicine, 1024 Welch Rd, MC 5488, Stanford, CA 94305; and Department of Medical Quantitative Health, University of Florida, Gainesville, Fla (W.S.).

Purpose To compare diffusion-weighted imaging (DWI) with thermal dosimetry as a noncontrast method to predict ablation margins in individuals with prostate cancer treated with MRI-guided focused ultrasound (MRgFUS) ablation. Materials and Methods This secondary analysis of a prospective trial (ClinicalTrials.gov no.

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Article Synopsis
  • Variation exists in diagnosing and treating neurogenic thoracic outlet syndrome (NTOS), causing challenges in standardizing outcomes and practices among hand surgeons.
  • An international group of expert hand surgeons reached a consensus on guidelines for diagnosing and managing NTOS using the Delphi method, confirming 17 key statements.
  • Recommendations include a specific diagnostic approach, prioritizing conservative management, routine preoperative imaging, and surgical techniques for effective NTOS treatment.*
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