The effects of region-specific resistance and aerobic exercises on bone mineral density in premenopausal women.

Epidemiological, cross-sectional, and prospective studies strongly suggest that exercise has beneficial effects on bone mass in premenopausal women. We prospectively compared the effects of resistance or aerobic exercises on regional bone mass in premenopausal active duty military women ranging in age from 19 to 40 years. Subjects were assigned, by preference, to a resistance exercise group or an aerobic exercise group and instructed to exercise at least 30 minutes per day, three times per week, for a period of 1 year.

Failure of gamma-interferon to decrease mortality from group B streptococcal sepsis in neonatal rats.

Newborns possess an altered immune response to infection with impaired leukocyte chemotaxis and deficient production of gamma-interferon (IFN-gamma). IFN-gamma enhances neonatal leukocyte activation and movement. We proposed that IFN-gamma in conjunction with penicillin compared to penicillin therapy without IFN-gamma would increase survival from group B streptococcal sepsis in a neonatal rat model.

A prospective, multidisciplinary evaluation of premenopausal women with iron-deficiency anemia.

Objective: The cause of iron deficiency anemia (IDA) in premenopausal women is often presumed to be menstrual blood loss. The purpose of this study was to determine the diagnostic value of a comprehensive gynecological and gastrointestinal evaluation in premenopausal women with IDA.

Methods: Nineteen premenopausal, nonpregnant women older than 18 yr of age with IDA defined by a hemoglobin < 12 gm/dl with serum ferritin < 10 ng/ml participated in the study.

Endoscopic ultrasound localization of a pancreatic insulinoma: case report and review of the localization techniques.

A 23-year-old male was referred to our hospital for evaluation of new-onset seizures. Signs and symptoms of neuroglycopenia, including weakness, dizziness, and confusion, appeared during fasting and resolved promptly with intravenous dextrose administration. Insulin, proinsulin, and C-peptide levels were consistent with a diagnosis of insulinoma.

Physical and sexual abuse in female patients with fibromyalgia.

Sexual and physical abuse during childhood seem to be common. The purpose of this study was to determine the prevalence of sexual and physical abuse reported by female fibromyalgia (FM) patients in a referral-based rheumatology practice, and whether patients with FM report greater frequencies of abuse than do patients with rheumatoid arthritis (RA).Patients from two tertiary care centers, 205 with FM and 84 with RA, were mailed a self-administered questionnaire requesting information about demographics, mental health care use, and history of sexual and/ or physical abuse.

Patient certification through mutual problem lists.

Objective: To determine whether retired military personnel and spouses are cognizant of the patient's complete list of medical problems.

Methods: Receiving help from their spouses or other personal care givers, 12 patients listed their health problems from memory plus from a page-by-page review of their permanent medical records. The personal physician produced his own lists and combined them with the patient-generated lists.

Antigen-specific antibody responses in lupus patients following immunization.

Objective: To determine the safety and efficacy of 3 clinically relevant vaccines in patients with systemic lupus erythematosus (SLE).

Methods: We studied 73 consecutive SLE patients immunized with pneumococcal, tetanus toxoid (TT), and Haemophilus influenzae type B (HIB) vaccines. Patients were evaluated preimmunization and 12 weeks postimmunization for disease activity and immunization side effects.

Postpneumonectomy pulmonary edema: can it be predicted preoperatively?

Postpneumonectomy pulmonary edema (PPE) is a rarely reported form of acute lung injury which occurs in up to 4% of all pneumonectomies. The details of two well-documented cases of PPE are described with special emphasis paid to the preoperative lung functions. Both cases illustrated a striking disparity between preserved spirometric lung function and advanced emphysema as detected by quantitative CT emphysema scores and single-breath diffusion of carbon monoxide measurements.

Prospective validation of a scoring system for predicting neonatal morbidity after acute perinatal asphyxia.

Objective: To prospectively validate a previously reported scoring system for identifying the near-term infant at risk for the multiple organ system sequelae of acute perinatal asphyxia.

Study Design: Prospective observational study.

Setting: Three Denver teaching hospitals, each providing comprehensive obstetric care.

Mugwort and sage (Artemisia) pollen cross-reactivity: ELISA inhibition and immunoblot evaluation.

Background: Plants of the genus Artemisia are a source of fall allergic symptoms, particularly in the western United States. Studies have characterized the allergens in one of the major species (A. vulgaris) but currently there are no cross-reactivity data on the major United States species.

Learning from the last ultrasound. A population-based study of patients with abdominal aortic aneurysm.

Background: Patients with abdominal aortic aneurysm often are followed up with serial ultrasound examinations, but published studies usually describe rupture risk according to the diameter of the abdominal aortic aneurysm at diagnosis rather than by most recent ultrasound. Information in this form is misleading when used to predict prognosis.

Methods: We used data from the population-based cohort of residents of Rochester, Minn, diagnosed as having abdominal aortic aneurysm who have had at least 1 ultrasound measurement.

Atmospheric mold spore counts in relation to meteorological parameters.

Fungal spore counts of Cladosporium, Alternaria, and Epicoccum were studied during 8 years in Denver, Colorado. Fungal spore counts were obtained daily during the pollinating season by a Rotorod sampler. Weather data were obtained from the National Climatic Data Center.

Attempt to correlate urine arsenic excretion with clinical course during melarsoprol therapy of patients with Rhodesian trypanosomiasis.

This study enrolled 28 CNS-involved patients with Trypanosoma brucei rhodesiense at the Kenya Trypanosomiasis Research Institute (Alupe, Kenya) to examine treatment efficacy and toxicity of melarsoprol in relation to renal excretion/dose relationships. This study complied with World Health Organization treatment recommendations, initially treating with suramin followed by three courses of melarsoprol. Traced study patients had a relapse rate of 4.

Indium In-111 pentetreotide scintigraphy: application to carotid body tumors.

Purpose: This study was conducted to investigate and illustrate the use of Indium In-111 pentetreotide scintigraphy as it applies to carotid body tumors (CBT). Localization has relied primarily on ultrasonography, computed tomography, and magnetic resonance imaging with angiographic confirmation. These methods only assess the cervical bifurcation without providing an evaluation of metastasis in patients without symptoms or recurrence in patients after surgery.

5-Fluorouracil reduces scarring after strabismus surgery.

Purpose: To examine the effect of topically administered 5-fluorouracil during strabismus surgery on post-operative scarring and the strength of the tendon-muscle union.

Methods: Bilateral superior and inferior rectus muscle recessions were performed on 10 Stauffland white rabbits. The operated muscles in one eye received a 5-min topical application of 50 mg/mL solution of 5-fluorouracil (5-FU).

Hypertrophic cardiomyopathy presenting with 3rd-degree atrioventricular block.

A 15-year-old boy presented with exercise intolerance and near syncope. Electrocardiography showed 3rd-degree atrioventricular block. He was treated emergently with temporary transvenous ventricular pacing.

Vulvar metastasis of breast carcinoma. A case report.

Background: Metastasis of breast carcinoma to the vulva is rare: only a few cases have been previously described.

Case: A 61-year-old woman with a history of recurrent breast carcinoma presented with a painless lump on the vulva. Excisional biopsy showed an infiltrating adenocarcinoma that was histologically similar to the primary breast tumor.

Initial success and substantial government savings may mandate prime vendor contracts for Table of Organization and Equipment units and development support.

In November 1994, the Department of Pharmacy at Madigan Army Medical Center and the 62nd Medical Group Logistics (Fort Lewis, Washington) examined the feasibility of prime vendor support for the 18th Mobile Army Surgical Hospital in a Table of Organization and Equipment (TOE) unit rapid deployment. The TOE medication list was deemed to be out of date and a state-of-the-art formulary was developed. By identifying three National Drug Code bioequivalent substitutes for each National Stock Number, a 94% prime vendor match was achieved for pharmaceuticals form the new formulary serving as our template.

Orbital and eyelid manifestations of neurofibromatosis: a clinical study and literature review.

Neurofibromatosis (NF) is an autosomal dominant abnormality that may effect multiple organ systems. Eyelids, orbits, and adjacent tissues may be involved with varying frequency and severity. Plexiform neurofibromas, causing mechanical ptosis and proptosis, optic nerve gliomas, and sphenoid wing dysplasia are some of the more common orbital and eyelid findings in NF.

Adjuvant radiation therapy for low stage testicular seminoma: Diagnosis and therapy in evolution.

We performed a retrospective study to evaluate the clinical outcome of patients with early stage testicular seminoma who received adjuvant radiation therapy after orchiectomy over the past 15 years. During the 15 year period, 61 patients were treated with adjuvant radiation therapy for stages I, IIA, and IIB testicular seminoma. Patients received from 2,000 to 4,000 cGy delivered by a Cobalt machine and later by a linear accelerator.