1,007 results match your criteria: "First-Degree Atrioventricular Block"
Bradyarrhythmias in patients with embolic stroke of undetermined source: a tight relationship with atrial cardiomyopathy.
Neurol Sci
December 2024
Division of Cardiology, Cardio-Thoracic Department, University Hospital of Verona, Verona, Italy.
Background: Implantable loop recorders (ILRs) have been shown to significantly improve the detection of atrial fibrillation (AF) in patients with embolic stroke of undetermined source (ESUS). The incidence and characterization of bradyarrhythmias in this subset of patients is still unknown.
Methods: All consecutive patients who received ILRs, after an ESUS, between March 2015 and December 2022 in our Center were retrospectively enrolled and analyzed.
Short RP Interval and Long PR Interval: What Is the Cardiac Rhythm?
JACC Case Rep
November 2024
Division of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Marked first-degree atrioventricular block with a PR interval ≥500 ms is rare, leading to unusual P-wave placement. In this case, the P waves immediately after the QRS waves complicated rhythm interpretation. Close attention to P-wave morphology and fused premature ventricular complexes can be important for a proper diagnosis.
View Article and Find Full Text PDFAmyloidosis and the Syncopal Enigma.
J Prim Care Community Health
December 2024
Mayo Clinic, Rochester, MN, USA.
Background: Syncope is a common presenting complaint in the outpatient setting and requires a thoughtful and meticulous approach to history-taking skills. This is crucial in discerning cardiac versus non-cardiac etiologies, underscoring the pivotal role of healthcare professionals in the diagnostic process.
Case Report: This is a case of a 76-year-old male who presented to the primary care clinic following an episode of syncope with abrupt loss of consciousness.
Prophylactic Permanent Pacemaker Implantation for Baseline Right Bundle Branch Block in Patients Undergoing Transcatheter Aortic Valve Replacement: Clinical Efficacy, Safety, and Long-Term Pacing Requirement.
Struct Heart
November 2024
Oxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Background: Baseline right bundle branch block (RBBB) is an established predictor of permanent pacemaker (PPM) requirement after transcatheter aortic valve replacement (TAVR). There are limited data to support prophylactic PPM implantation in advance of TAVR. We aimed to evaluate the efficacy and safety of prophylactic PPM implantation in patients with RBBB prior to TAVR, and to identify the predictors of pacing dependence after TAVR.
View Article and Find Full Text PDFProgression and prognostic significance of electrocardiographic findings in patients with cardiac amyloidosis.
ESC Heart Fail
December 2024
Tuscan Regional Amyloidosis Centre, Careggi University Hospital, Florence, Italy.
Aims: This study aimed to evaluate the change of the main electrocardiographic (ECG) characteristics and their prognostic role across the main subtypes of cardiac amyloidosis [light-chain amyloidosis (AL) and hereditary (ATTRv) and wild-type transthyretin amyloidosis (ATTRwt)].
Methods And Results: This multicentre, retrospective study was performed in six referral centres for cardiac amyloidosis. Clinical and ECG data were collected at the first and last evaluations.
Vascular function assessed by flow-mediated vasodilation and nitroglycerine-induced vasodilation in subjects with first-degree atrioventricular block.
Sci Rep
December 2024
Department of Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Article Synopsis
Universal representations in cardiovascular ECG assessment: A self-supervised learning approach.
Int J Med Inform
December 2024
Center for Artificial Intelligence in Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan; School of Medicine, Chang Gung University, Taoyuan, Taiwan; Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan. Electronic address:
Article Synopsis
Pulsed Field Ablation of Paroxysmal Supraventricular Tachycardia: A Prospective Multicenter Single-Arm Study in China.
Circ Arrhythm Electrophysiol
December 2024
Department of Cardiology (F.L., A.G., H.H., K.C., Q.Y., X.P., S.C., J.J., H.F., H.W., T.Y., X.H., Y.T., Q. Zhang, R.Z.), , West China Hospital of Sichuan University, Chengdu.
Background: Pulsed field ablation (PFA) has gained attention in cardiac electrophysiology, but data on its application to paroxysmal supraventricular tachycardia are limited. This study aimed to assess the feasibility and safety of PFA and its combination with radiofrequency ablation for treating paroxysmal supraventricular tachycardia.
Methods: A prospective, multicenter, single-arm study was conducted across 8 centers in China.
Atrioventricular nodal re-entrant tachycardia unmasking cardiac sarcoidosis: a clinical case report.
Eur Heart J Case Rep
October 2024
Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.
Article Synopsis
- Sarcoidosis is a rare condition that can affect the heart, leading to various symptoms from mild issues to severe complications like heart failure and sudden death.
- A case was presented where a female patient experienced AV nodal re-entrant tachycardia, an unusual first sign of cardiac sarcoidosis, along with other heart rhythm disturbances.
- Awareness of the potential for rare presentations like supraventricular tachycardia is vital for early diagnosis, as it can help prevent sudden cardiac death, prompting the need for devices like implantable cardioverter-defibrillators for some patients.
A multicenter study of clinical predictors of positive pyrophosphate scintigraphy findings in the diagnosis of transthyretin amyloidosis.
Int J Cardiol
January 2025
Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan.
Article Synopsis
- - The study focuses on the increasing detection of wild-type transthyretin (ATTR) amyloidosis and evaluates the effectiveness of Tc-labeled pyrophosphate (Tc-PYP) scintigraphy for diagnosing ATTR cardiac amyloidosis in patients across Japan from 2018 to 2022.
- - Out of 180 patients, 135 were analyzed, with 62 testing positive for Tc-PYP; researchers developed a scoring system based on five clinical factors to predict positivity, revealing that a higher score correlates with a greater likelihood of positive results.
- - The study concludes that combining commonly available clinical data can significantly enhance the pretest prediction accuracy for Tc-PYP scintigraphy, aiding clinicians in the early diagnosis of ATTR amyloidosis
Prevalence of prolonged QTc interval among HIV infected patients on highly active antiretroviral therapy (HAART) and its relationship with CD4 cells count and viral load at a tertiary hospital in North Eastern Nigeria.
Niger Med J
September 2024
Yobe State University College of Medical Sciences Damaturu, Nigeria.
Article Synopsis
- HIV-infected patients face a higher risk of cardiovascular issues, with varying prevalence rates of electrocardiographic (ECG) abnormalities reported, ranging from 34.5% to as high as 93.0%.
- In a study conducted on HIV patients receiving HAART in Nigeria, 18.7% were found to have a prolonged QTc interval, which can lead to serious heart complications.
- The sample included 107 participants, with sinus rhythm being the most common ECG finding, while other abnormalities like premature ventricular contractions and different types of heart blocks were also observed.
When Is Mitral Regurgitation Not Just Systolic?: A Case of Near-Continuous Mitral Regurgitation.
JACC Case Rep
September 2024
Department of Cardiology, Cleveland Clinic, Abu Dhabi, United Arab Emirates.
Article Synopsis
- A 30-year-old man showed serious symptoms from severe chronic aortic regurgitation and issues with his heart's electrical signals and mitral valve.
- He underwent successful surgery that involved replacing the aortic root and repairing the mitral valve.
- This case underscores the connection between different heart valve diseases and the need for thorough evaluation for effective treatment.
A case of propafenone toxicity in the setting of dehydration and acute kidney injury.
Glob Cardiol Sci Pract
August 2024
Department of Cardiology, Jefferson Abington Hospital, Abington, PA, USA.
Article Synopsis
- Propafenone is a class 1C antiarrhythmic medication commonly used to treat atrial fibrillation, but its toxicity, though rare, can be serious and lead to complications like hypotension and cardiac arrest.
- An 80-year-old male patient experienced symptoms caused by dehydration from excessive diuresis, resulting in serious changes on his ECG that were linked to propafenone toxicity.
- Managing the patient's fluid levels and temporarily stopping propafenone led to quick improvement in his heart rhythm, highlighting the need to consider factors like volume status when dealing with propafenone toxicity.
Dilated cardiomyopathy revealing Refsum disease: a case report.
J Med Case Rep
September 2024
Cardiology Department, Ibn Rochd Hospital University, Casablanca, Morocco.
Article Synopsis
- Refsum disease is a rare genetic disorder affecting lipid metabolism, leading to the buildup of phytanic acid and resulting in symptoms like ataxia, neuropathy, and hearing loss, with potential cardiac issues developing later in life.
- A case study presented a 38-year-old man who experienced acute heart failure due to dilated cardiomyopathy, confirmed by high levels of phytanic acid, illustrating that cardiac problems are common in advanced Refsum disease.
- Management options for Refsum disease include dietary restrictions on phytanic acid and lipid apheresis to alleviate symptoms and improve patients' quality of life.
Phenome-Wide Association of Alleles in the Research Program.
medRxiv
September 2024
Department of Pharmacy Practice and Science, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ, USA.
Article Synopsis
- Genetic variations in specific genes are linked to differences in lipid metabolism and risks for cardiovascular and neurodegenerative diseases, but previous studies mainly focused on European populations and didn't extensively consider sex or ancestry differences.
- This study analyzed genetic data from 181,880 participants across seven ancestry groups to identify associations with various health conditions, specifically looking at phenotypes related to Alzheimer's disease risk.
- The findings revealed significant associations with conditions like hyperlipidemia and Alzheimer's, highlighting differences in these risks based on sex and ancestry, while also noting that there were some unique associations in specific ancestry groups.
Real-world battery longevity of implantable loop recorders implanted for unexplained syncope: Results from a large single-center registry.
J Cardiovasc Electrophysiol
November 2024
Department of Cardiology, Heart Center, Ghent University Hospital, Ghent, Belgium.
Article Synopsis
- Implantable loop recorders (ILRs) are used for monitoring heart rhythms in patients with unexplained fainting (syncope), and this study investigated how long their batteries actually last in real-world settings.
- The study followed 309 patients over several years, finding that ILRs had a median battery life of 42 months, with nearly all (99.5%) reaching or exceeding the expected lifespan.
- It also revealed that the diagnostic yield for identifying arrhythmias was relatively low at 27%, although diagnostic rates improved over time, highlighting the importance of prolonged monitoring for better diagnosis.
First report of the clinical characteristics and outcomes of cardiac amyloidosis in Saudi Arabia.
ESC Heart Fail
December 2024
College of Medicine, Al Faisal University, Riyadh, Saudi Arabia.
Article Synopsis
- The study focuses on cardiac amyloidosis (CA), a serious disease that is often overlooked, particularly in the Middle East, and aims to assess its prevalence and characteristics in a high-risk group in Saudi Arabia.
- It was a retrospective study conducted on heart failure patients at a hospital in Riyadh, using specific "red flags" like carpal tunnel syndrome and echocardiographic signs to identify those needing screening for CA.
- Out of 177 patients screened, 11.9% were diagnosed with transthyretin amyloid CA and 7.3% with light chain CA, noting that those with positive accompanying scans tended to be older.
Sex-specific cardiovascular risk factors in the UK Biobank.
Front Physiol
April 2024
Department of Mechanical Engineering, Stanford University, Stanford, CA, United States.
Article Synopsis
- ! The existing cardiovascular disease risk assessment methods, like the Framingham Risk Score, fail to adequately account for differences between men and women, leading to underdiagnosis of female patients. * ! Utilizing data from the UK Biobank and machine learning techniques, researchers aim to create more precise cardiovascular risk models that address these disparities and include more varied biomedical data. * ! The study highlights significant underdiagnosis rates for women in certain heart conditions and emphasizes the importance of developing sex-specific diagnostic criteria to improve risk prediction and treatment interventions in cardiovascular health. * !
Electrocardiogram Abnormalities in Children With Lyme Arthritis.
Pediatr Infect Dis J
August 2024
From the Division of Emergency Medicine.
Article Synopsis
- A study investigated the prevalence of ECG abnormalities in children diagnosed with Lyme arthritis to understand if there is an overlap with carditis, which commonly occurs in early Lyme disease.
- Out of 233 pediatric patients with Lyme arthritis, only 90 had ECGs performed, and abnormalities were found in 5.6% of these cases, including instances of first-degree atrioventricular block and QTc prolongation.
- The findings suggest that such ECG abnormalities are rare and do not indicate clinically significant heart issues, implying that routine ECG screening for asymptomatic kids with Lyme arthritis is unnecessary.
Vancomycin Anaphylaxis and Kounis Syndrome Case Report.
Cureus
July 2024
Trauma and Acute Care Surgery, Grand Strand Medical Center, Myrtle Beach, USA.
Article Synopsis
- A 67-year-old man experienced severe complications, including hypotension and heart issues, after receiving preoperative vancomycin for a knee surgery.
- The report details the emergency response to his cardiovascular collapse, highlighting successful medical management leading to his full recovery.
- This case emphasizes the risks of preoperative antibiotics and the necessity for personalized patient care to ensure safety during surgical procedures.
Feasibility and findings of electrocardiogram recording in older adults with intellectual disabilities: results of the Healthy Ageing and Intellectual Disabilities study.
J Intellect Disabil Res
December 2024
Department of General Practice, Intellectual Disability Medicine, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.
Article Synopsis
- - Older adults with intellectual disabilities are at a high risk for cardiovascular diseases, and traditional diagnostic methods often overlook these issues, prompting the need for objective assessments like ECGs.
- - A study found that ECG recording was feasible for 67% of participants aged 60 and older with intellectual disabilities, revealing a high prevalence of abnormalities, with 77% diagnosed with at least one issue.
- - The most common ECG abnormalities included prolonged P-wave duration and QTc prolongation, with a significant portion of myocardial infarction cases being previously undiagnosed in the participants' medical records.
Management of Postprocedural Conduction Disturbances Using a Prespecified Algorithm in the Optimize PRO Study.
J Soc Cardiovasc Angiogr Interv
January 2024
Quebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
Article Synopsis
- * Optimize PRO, a prospective study, implements two strategies: using a cusp overlap technique during TAVR and a CD algorithm that assesses patients based on their post-procedure ECG for early discharge decisions.
- * Results indicate that patients with conduction disturbances had a significantly higher PPI rate at 30 days compared to those without (28.1% vs 1.5%), but the standardized management of CDs led to similar safety outcomes, suggesting effective early recognition and monitoring of arrhythm
Dual challenge inside the womb: a case report of concomitant fetal atrio-ventricular block associated with maternal anti-SSA antibodies and fetal tachyarrhythmia diagnosed as Wolff-Parkinson-White syndrome after birth.
Front Immunol
August 2024
Rheumatology Department, Unidade Local de Saúde do Hospital de Santa Maria, Lisbon, Portugal.
Article Synopsis
- - Fetal autoimmune atrioventricular block (AVB) is a rare condition caused by maternal anti-SSA/Ro or Anti-SSB/La auto-antibodies affecting the fetal heart, leading to serious issues like inflammation and damage to the AV node.
- - A patient with a history of high antibody levels and hypothyroidism showed improvements in a first-degree AV block during pregnancy after treatment with dexamethasone and intravenous immunoglobulin.
- - The fetus later developed a tachyarrhythmia requiring medication, and after birth, was diagnosed with Wolff-Parkinson-White Syndrome (WPWS), marking the first known instance of AVB co-existing with WPWS.
Predictors and Trends of New Permanent Pacemaker Implantation: A Subanalysis of the International Navitor IDE Study.
Struct Heart
July 2024
Cardiovascular Institute, Hospital Corporation of America, Los Robles Regional Medical Center, Thousand Oaks, California, USA.
Article Synopsis
- - The Navitor IDE study examines the safety and effectiveness of the Navitor valve for patients with severe aortic stenosis who are at high surgical risk, focusing on the connection between patient factors and the rate of new permanent pacemaker implantation (PPI) within 30 days post-surgery.
- - Researchers analyzed data from 260 patients, excluding those with prior pacemakers, and found that specific conduction abnormalities, like first-degree atrioventricular block and right bundle branch block, increased the likelihood of new PPI, while the depth of the valve implantation also played a significant role.
- - The study concludes that both existing conduction issues and the surgical technique (implant depth) are critical predictors of whether patients will need a new pacemaker
Electrocardiographic abnormalities are frequently detected in healthy adult Borzoi with a normal echocardiogram.
J Am Vet Med Assoc
October 2024
1Department of Small Animal Clinical Sciences, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX.
Article Synopsis
- - The study aimed to investigate ECG characteristics and abnormalities in clinically healthy Borzoi dogs to understand their risk for sudden death, involving 98 dogs between October 2020 and December 2022.
- - Among the 82 Borzoi with normal echocardiograms, 10% exhibited ventricular arrhythmias, and a significant portion (38%) had first-degree atrioventricular block, alongside many showing signs of early repolarization and prolonged QT intervals.
- - The findings suggest that clinically healthy Borzoi may have several heart-related abnormalities that could lead to sudden death, indicating a need for further research on genetic heart issues in this breed and the establishment of specific ECG reference intervals.