402 results match your criteria: "First Medical Center of PLA General Hospital.[Affiliation]"
Front Bioeng Biotechnol
February 2023
Beijing Institute of Dental Research, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
We investigated the current state and trends in the area during the previous 10 years using bibliometric approaches to evaluate the global scientific output of research on electroactive materials and spinal cord injury. Studies on spinal cord injury in electroactive materials that were published between 2012 and 2022 were located using the Web of science (WOS) datebase. The software programs bibliometrix R-package and CiteSpace were used to do quantitative analyses of annual publications, nation, author, institution, journal source, co-cited references, and keywords.
View Article and Find Full Text PDFGland Surg
February 2023
Department of Ultrasound, The First Medical Center of PLA General Hospital, Beijing, China.
Background: Mass-like (ML) and non-mass-like (NML) are two manifestations of breast lesions on ultrasound. Contrast-enhanced ultrasound (CEUS) can make up for the limitation of B-ultrasound (US) in the observation of focal blood flow, and shear wave elastography (SWE) can supplement the hardness information of the lesion. The present study aimed to analyze the characteristic manifestations of US, CEUS, and SWE in NML and ML breast and evaluate whether the diagnostic performance of these three ultrasound techniques differs in terms of differentiating between benign and malignant breast lesions.
View Article and Find Full Text PDFJ Oncol
March 2023
Department of Radiation Medicine, Faculty of Naval Medicine, Naval Military Medical University, Shanghai 200433, China.
NSCLC (non-small-cell lung cancer) is an aggressive form of lung cancer and accompanies high morbidity and mortality. This study investigated the function and associated mechanism of MMP10 during radiotherapy of NSCLC. MMP10 expression in patients and their overall survival rate were assessed through GEPIA.
View Article and Find Full Text PDFInt J Colorectal Dis
March 2023
Nankai University School of Medicine, Nankai University, Tianjin, 300071, China.
Background: Melanosis coli is characterized by brown mucosa with pigmentation. Studies have showed an increased adenoma detection rate in melanosis patients, whether it is caused by a contrast effect or an oncogenic effect is still controversial. The detection of serrated polys in melanosis patients remains unknown.
View Article and Find Full Text PDFEur J Haematol
June 2023
Senior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Objectives: The advanced extra-nodal NK/T-cell lymphoma (ENKTL) is highly aggressive and lacks effective treatment with a poor prognosis. This study aimed to investigate the effectiveness and safety of autologous hematopoietic stem cell transplantation (ASCT) in CR1.
Methods: Forty of 121 patients with advanced ENKTL from four Chinese hospitals between January 2006 to December 2021 who achieved first complete remission (CR1) and received at least 4 cycles chemotherapy, were enrolled for analysis.
Zhonghua Nei Ke Za Zhi
March 2023
Department of Endocrinology, the First Medical Center of PLA General Hospital, Beijing 100853, China.
To investigate the association between reproductive lifespan duration (RLD) and urinary albumin-creatinine ratio (UACR) in a Chinese postmenopausal population. This cross-sectional study included 11 055 naturally postmenopausal women from seven regions of China from May to December 2011. RLD was divided into four groups.
View Article and Find Full Text PDFAnn Transl Med
January 2023
Department of Ultrasound, The First Medical Center of PLA General Hospital, Beijing, China.
Front Cardiovasc Med
February 2023
Department of Vascular and Endovascular Surgery, The First Medical Center of PLA General Hospital, Beijing, China.
Objective: This study was performed to develop a murine model of elastase-induced proximal thoracic aortic aneurysms (PTAAs).
Methods: The ascending thoracic aorta and aortic arch of adult C57BL/6J male mice were exposed through a midline incision in the anterior neck, followed by peri-adventitial elastase or saline application. The maximal ascending thoracic aorta diameter was measured with high-resolution micro-ultrasound.
Front Neurol
February 2023
Senior Department of Neurology, The First Medical Center of PLA General Hospital, Beijing, China.
Objective: To explore the values of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), neutrophil to albumin ratio (NAR), prognostic nutritional index (PNI), systemic immune inflammatory index (SII) and red cell distribution width to albumin ratio (RA) for evaluating the risk of 30-day mortality of ischemic stroke or hemorrhagic stroke patients.
Methods: In this cohort study, the data of 1,601 patients diagnosed with stroke were extracted from the Medical Information Mart for Intensive Care III (MIMIC-III) database. Among them, 908 were hemorrhagic stroke patients and 693 were ischemic stroke patients.
Ann Transl Med
January 2023
Department of Anesthesiology, The Sixth Medical Center of PLA General Hospital, Beijing, China.
Background: Stroke volume variation (SVV) and pulse pressure variation (PPV) are based on the interaction between the heart and lungs during mechanical ventilation. However, debate continues as to whether SVV and PPV can accurately predict fluid responsiveness during the one-lung ventilation (OLV). We therefore undertook a systematic review and meta-analysis of clinical trials that investigated the diagnostic value of SVV and PPV in predicting fluid responsiveness undergoing OLV during thoracic surgery.
View Article and Find Full Text PDFComput Biol Med
March 2023
Department of Stomatology, The First Medical Center of PLA General Hospital, Beijing, 100853, China. Electronic address:
This in vitro study aimed to put forward the development and investigation of a novel Mixed Reality (MR)-based dental implant navigation method and evaluate implant accuracy. Data were collected using 3D-cone beam computed tomography. The MR-based navigation system included a Hololens headset, an NDI (Northern Digital Inc.
View Article and Find Full Text PDFFront Surg
January 2023
Department of Science and Education Section, People's Hospital of Xuanhan County, Dazhou, China.
Objective: The aim of this study was to determine whether the addition of esketamine to morphine would improve postoperative analgesia after cesarean section.
Methods: Parturients who planned for a cesarean delivery using combined spinal-epidural anesthesia with a request for postoperative anesthesia were randomly divided into four groups (A, B, C, and D). When the surgery was completed, the parturients in groups A, B, C, and D were administered 2 mg morphine, 0.
Front Surg
January 2023
Department of Anesthesiology, The First Medical Center of PLA General Hospital, Beijing, China.
Objective: To determine whether intraoperative transfusion of allogeneic or autologous blood is associated with an increased incidence of postoperative delirium (POD) after total knee arthroplasty (TKA) and total hip arthroplasty (THA).
Methods: The medical records of 1,143 older (≥65 years old) patients who received an intraoperative blood transfusion while undergoing total knee or hip arthroplasty at the First Medical Center of Chinese PLA General Hospital from 2014 to 2019 were reviewed; of these patients, 742 (64.92%) received allogeneic blood, while 401 (35.
Brain Sci
January 2023
Department of Neurology, School of Medicine, South China University of Technology, Guangzhou 510006, China.
Objective: To explore the characteristics and dynamic evolution of cognitive impairment in patients with neuromyelitis optica spectrum disorder (NMOSD). Methods: Twenty-five patients with acute NMOSD and 30 age-matched healthy individuals were consecutively recruited in this study. The Montreal Cognitive Assessment (MoCA), Chinese Version of Rey Auditory Vocabulary Learning Test (CRAVLT), Verbal Fluency Test (VFT), Digital Span Test (DST), Paced Auditory Serial Addition Task 3/2s version (PASAT-3/2), Rey−Osterrieth Complex Figure Test (ROCF) and Stroop Color and Word Test (CWT) were used to evaluate cognitive function.
View Article and Find Full Text PDFDig Liver Dis
July 2023
Department of Interventional Radiology, The First Medical Center of PLA General Hospital, Beijing 100853, China. Electronic address:
Background: To evaluate the safety and the long-term outcomes of transarterial embolization (TAE) with lipiodol-bleomycin emulsion (LBE) plus N-Butyl cyanoacrylate (NBCA) in the treatment of children with large symptomatic focal nodular hyperplasia (FNH).
Methods: This is a retrospective case serial study. Children (aged <18 years) with FNH were treated.
Anal Chem
January 2023
School of Chemical and Engineering, Nanjing University of Science and Technology, Jiangsu 210094, China.
Cardiac troponin I (cTnI) is the biomarker of choice and considered a gold standard for the diagnosis of acute myocardial infarction. However, the quantitative results of cTnI assay kits from different manufacturers are not comparable. Based on the H/D exchange mass spectrometry (HDX-MS) workflow, we developed an in-vitro diagnostic reagent antibody evaluation strategy to analyze the interactions of epitopes and antibody cocktails─(R195, F12, S13) and (D1, D2, pAb2).
View Article and Find Full Text PDFTechnol Cancer Res Treat
January 2023
Department of Radiation Oncology, National Cancer Center/Cancer Hospital, 12501Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
To investigate and compare 2 cone-beam computed tomography (CBCT) correction methods for CBCT-based dose calculation. Routine CBCT image sets of 12 head and neck cancer patients who received volumetric modulated arc therapy (VMAT) treatment were retrospectively analyzed. The CBCT images obtained using an on-board imager (OBI) at the first treatment fraction were firstly deformable registered and padded with the kVCT images to provide enough anatomical information about the tissues for dose calculation.
View Article and Find Full Text PDFBMC Pulm Med
January 2023
Department of Oncology, The First Medical Center of PLA General Hospital, Beijing, China.
Background: Patients with pulmonary large cell carcinoma (LCC) have a high incidence of synchronous brain metastases (SBM) and a poor prognosis. Our study was to evaluate the predictive and prognostic value of the clinical characteristics of pulmonary LCC patients with SBM at initial diagnosis by utilizing the Surveillance, Epidemiology, and End Results (SEER) database.
Methods: LCC patients, diagnosed from 2010 to 2019, were identified from the latest SEER database which was released in April 2022.
BMC Gastroenterol
January 2023
Senior Department of Gastroenterology, the First Medical Center of PLA General Hospital, Beijing, China.
Background: To explore the causes of endoscopic misdiagnosis of gastrointestinal cyst as solid lesion and the diagnostic value and limitations of EUS, guide clinicians to develop appropriate treatment strategies and improve the ability to identify SMT.
Methods: We enrolled patients diagnosed with gastrointestinal SMT between January 2001 and December 2021 who underwent endoscopic resection with postoperative pathological diagnosis of cyst. Age, sex, maximum lesion diameter, judge the texture of lesion, origin and echo are potential factors affecting the diagnostic accuracy of cysts.
Zhonghua Nei Ke Za Zhi
January 2023
Department of Rheumatology and Immunology, the First Medical Center of PLA General Hospital, Beijing 100853, China.
The study aimed to analyze the efficacy and safety of rituximab in the treatment of 23 cases of lupus nephritis and explore the prospect of half-dose rituximab in lupus nephritis treatment. Twenty-three patients with lupus nephritis hospitalized in the Department of Rheumatology and Immunology at the First Medical Center of the PLA General Hospital from May 2013 to December 2021 were selected. Eighteen patients received rituximab 375 mg/m on the first and 14th days, 5 patients received 500 mg of rituximab on the first and 14th days, and rituximab was used as needed 6 months later.
View Article and Find Full Text PDFTechnol Cancer Res Treat
January 2023
Department of Oncology, The First Medical Center of PLA General Hospital, Graduate School, Medical College of Chinese PLA, Beijing, China.
In the era of precision medicine, with the deepening of the research on malignant tumor driving genes, clinical oncology has fully entered the era of targeted therapy. For non-small-cell lung cancer (NSCLC), the development of targeted drugs targeting driver genes, such as epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK), has successfully opened up a new model of targeted therapy. At present, proto-oncogene rearranged during transfection (RET) fusion gene is an important novel oncogenic driving target, and specific receptor tyrosine kinase inhibitors (TKIs) targeting RET fusion have been approved.
View Article and Find Full Text PDFTher Adv Neurol Disord
December 2022
Department of Pediatrics, PLA General Hospital, Beijing, China.
Background: Vigabatrin (VGB) is currently the most widely prescribed first-line medication for individuals with infantile spasms (IS) and especially for those with tuberous sclerosis complex (TSC), with demonstrated efficacy. Meanwhile, its adverse events, such as vigabatrin-associated brain abnormalities on magnetic resonance imaging (MRI; VABAM), have also been widely reported.
Objectives: The objectives of this study were to observe the occurrences of VABAM in patients with IS caused by TSC (IST) and further explore the associated risk factors.
Front Med
February 2023
Medical College of Guangxi University, Nanning, 530004, China.
Nasopharyngeal carcinoma (NPC) is a malignant tumor that mainly occurs in East and Southeast Asia. Although patients benefit from the main NPC treatments (e.g.
View Article and Find Full Text PDFAm J Reprod Immunol
March 2023
Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Purpose: Implantation is a limiting factor for treatment success in assisted reproduction. Both embryonic and endometrial factors contribute to implantation. Embryonic factors have often been ignored in previous studies about the role of endometrium in implantation.
View Article and Find Full Text PDFActa Odontol Scand
July 2023
Department of Stomatology, The Third Hospital of Shijiazhuang, Shijiazhuang, P.R. China.
Objective: Oral hygiene has been suspected to contribute to the aetiology of head and neck cancer (HNC). Based on the meta-analysis, we evaluated the impact of oral hygiene on head and neck cancer (HNC) and its survival.
Materials And Methods: Relevant case-control and cohort studies reporting survival data, oral hygiene data were searched PubMed, Embase, Cochrane Library, and Web of Science databases.