Bonding performance of dispersed filler resin composite CAD/CAM blocks with different surface treatment protocols.

The effect of various pretreatments on the bonding of a resin cement to resin-composite CAD/CAM blocks (RCBs) was examined. The surface of dispersed-filler RCBs (DF-RCBs) and a polymer infiltrated ceramic network RCB (PICN-RCB) was roughened using hydrofluoric acid etching (HF) or sandblasting, and followed by silanization and/or universal adhesive (UA) application. Microtensile bond strength (µTBS), surface roughness parameters (arithmetical mean height (Sa); developed interfacial area ratio (Sdr)), and critical surface energy (γ) were determined.

Long-term evaluation of warm-air treatment effect on adaptation of silane-containing universal adhesives to lithium disilicate ceramic.

The effect of warm air-blowing on the sealing ability of two one-bottle and one two-bottle silane-containing universal adhesives (UAs) applied to lithium disilicate ceramics (LDS) was evaluated. Tapered cavities prefabricated in LDS blocks (IPS e.max CAD) were treated by the adhesives, air-blown either with normal air (23±1°C) or warm air (60±5°C), and filled with a flowable resin composite.

A competing risk model for bond strength data analysis.

Objectives: A competing risk (CR) model distinguishing adhesive, cohesive and mixed failures as competing events was used for the analysis of micro-tensile bond strength (μTBS) data and compared with a conventional failure mode non-distinguishing survival model.

Methods: Fifty human molars were bonded using five universal adhesives (n = 10) and subdivided according to aging conditions (24-h water storage, thermocycling). After μTBS to dentin was tested, a fractographic analysis was performed using scanning electron microscopy.

CAD/CAM-fabricated inlay restorations: Can the resin-coating technique improve bond strength and internal adaptation?

This study assessed the effect of the resin-coating technique on the bond strength and internal adaptation of computer-aided design/computer-aided manufacturing (CAD/CAM)-fabricated inlays. Seventy-two mesio-occlusal-distal (MOD) cavities were prepared and distributed into 3 groups according to the resin-coating technique utilized: uncoated group, G-Premio Bond (1-step) group, and Clearfil SE Bond 2+Clearfil Majesty ES Flow (2-step+Flow) group. The MOD inlays were fabricated and cemented with RelyX Ultimate (RXU), G-CEM LinkForce (LinkForce), or Panavia V5 (PV5).

Air-blowing strategies for improving the microtensile bond strength of one-step self-etch adhesives to root canal dentin.

The effect of different air-blowing strategies using a prototype of a newly developed clinically applicable warm air-blowing device on the microtensile bond strength (μTBS) of one-step self-etch adhesives (1-SEAs) to human root-canal dentin was evaluated. Post cavities (8 mm depth, 1.5 mm diameter) were prepared and bonded with four 1-SEAs.

Effect of smear layer deproteinization with chemo-mechanical caries removal agents on sealing performances of self-etch adhesives.

Objectives: To evaluate the sealing performance of self-etch adhesives (SEA) after smear layer deproteinization with chemo-mechanical caries removal agents (CRA) to enamel and dentin cavity walls in comparison with 6% NaOCl smear layer deproteinizing.

Methods: Eighty extracted bovine incisors with tapered cylindrical cavities (2.5 mm upper diameter, 1.

Subsequent application of bonding agents to a one-step self-etch adhesive - Its effect with/without previous light-curing.

Objective: The influence of light-curing of a one-step self-etch adhesive (1-SEA) prior to the application of different bonding agents (BA) on the micro-tensile bond strength (μTBS) to dentin after 24h and thermal cycling was investigated. Additionally, the degree of conversion was evaluated using Fourier-transform infrared spectroscopy.

Methods: Three ion-releasing BAs, BZF-21 (experimental BA), Clearfil SE Protect (CSP), and FL-Bond II (FL-II), were applied subsequently to G-Premio Bond (1-SEA, GPB).

Ultra-high-speed videography of resin-dentin interface failure dynamics under tensile load.

Objectives: Ultra-high-speed (UHS) videography was used to visualize the fracture phenomena at the resin-dentin interface during micro-tensile bond strength (μTBS) test. We also investigated whether UHS videography is applicable for failure-mode analysis.

Methods: Ten human mid-coronal dentin surfaces were bonded using Clearfil SE Bond either in self-etching (SE) or etch-and-rinse (ER) mode.

Blood-based molecular signature of Alzheimer's disease via spectroscopy and metabolomics.

Objectives: With over 35 million cases worldwide, Alzheimer's disease (AD) represents the main cause of dementia. The differentiation of AD from other types of dementia is challenging and its early diagnosis is complicated. The established biomarkers are not only based on the invasive collection of cerebrospinal fluid, but also lack sufficient sensitivity and specificity.