2 results match your criteria: "First Affiliated Hospital of Guangxi University of Medical Sciences[Affiliation]"
[Detection of the activity of MMP2 and MMP9 in middle ear cholesteatoma].
Lin Chuang Er Bi Yan Hou Ke Za Zhi
October 2004
Department of Otolaryngology, First Affiliated Hospital of Guangxi University of Medical Sciences, Nanning, 530021, China.
Objective: To study the relationship between the activity of MMP2, and bone resorption in middle ear cholesteatoma.
Method: Specimens from 41 cases of middle ear cholesteatoma and 20 cases of external auditory canal skin were analysed for molecular corresponding to MMP2 and MMP9 by using Sodium Dodecyl Sulphate Polyacrylamide Gel Electrophoresis (SDS-PAGE) Zymography.
Result: The active levels of MMP2 and MMP9 in the cholesteatoma, which were (0.
[Expression of PTKs CDK4 and p15 in the middle ear cholesteatomatous epithelium].
Lin Chuang Er Bi Yan Hou Ke Za Zhi
October 2004
Department of Otolaryngology, First Affiliated Hospital of Guangxi University of Medical Sciences, Nanning, 530021, China.
Objective: To explore the cells proliferation and its molecular regulating mechanisms of cholesteatomatous epithelium from the aspect of protein tyrosine kinases (PTKs) signal transduction and cell cycle control.
Method: The expressions of phosphated PTKs, CDK4 and p15 were investigated by immunohistochemical S-P method and computer image analysis in 30 specimens of the middle ear cholesteatomatous epithelium and 19 specimens of external auditory canal epithelium from patients with chronic otitis media with cholesteatoma. The expressive results of phosphated PTKs, CDK4 and p15 were determined in same epithelium of different slices of same specimen.