7 results match your criteria: "Finnish Coordinating Center for Health Technology Assessment[Affiliation]"
Value of Pharmacogenetic Testing Assessed with Real-World Drug Utilization and Genotype Data.
Clin Pharmacol Ther
January 2025
Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.
Implementation of pharmacogenetic testing in clinical care has been slow and with few exceptions is hindered by the lack of real-world evidence on how to best target testing. In this retrospective register-based study, we analyzed a nationwide cohort of 1,425,000 patients discharged from internal medicine or surgical wards and a cohort of 2,178 university hospital patients for purchases and prescriptions of pharmacogenetically actionable drugs. Pharmacogenetic variants were obtained from whole genome genotype data for a subset (n = 930) of the university hospital patients.
View Article and Find Full Text PDFCost-effectiveness of shoulder arthroplasty for osteoarthritis and rotator cuff tear arthropathy. An economic analysis using real-world data.
Orthop Traumatol Surg Res
September 2024
Oulu University Hospital, Finnish Coordinating Center for Health Technology Assessment, Oulu, Finland.
Introduction: This study aimed to assess cost-effectiveness of shoulder arthroplasty for osteoarthritis (OA) and rotator cuff tear arthropathy (CTA) from the perspective of a publicly funded health care system using patient data, health utilities and costs from a real-world situation.
Hypothesis: Our hypothesis was that arthroplasty for OA is more cost-effective than for CTA.
Material And Methods: We gathered a cohort of patients with 153 anatomic total shoulder arthroplasty (TSA) for OA and 107 reverse shoulder arthroplasty (RSA) for CTA between years 2016-2020 at a university hospital.
Digital Care Pathway for Patients With Sleep Apnea in Specialized Care: Mixed Methods Study.
JMIR Hum Factors
February 2024
FinnTelemedicum, Research Unit of Health Sciences and Technology, Faculty of Medicine, University of Oulu, Oulu, Finland.
Background: Sleep apnea is a significant public health disorder in Finland, with a prevalence of 3.7%. Continuous positive airway pressure (CPAP) therapy is the first-line treatment for moderate or severe sleep apnea.
View Article and Find Full Text PDFReporting of costs and economic impacts in randomized trials of de-implementation interventions for low-value care: a systematic scoping review.
Implement Sci
August 2023
Finnish Medical Society Duodecim, Helsinki, Finland.
Article Synopsis
- * Methods: Researchers screened over 10,000 articles and included 227 studies, focusing on various interventions, costs of de-implementation, and their repercussions on healthcare expenses, using a modified risk of bias tool.
- * Results: Most studies were from North America and Europe, primarily in primary care, with 18% reporting direct costs and 19% examining the impact on healthcare costs—63% showed a decrease in costs, emphasizing a lack of thorough cost reporting in the majority of studies.
Randomized controlled trials in de-implementation research: a systematic scoping review.
Implement Sci
October 2022
Department of Urology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Article Synopsis
- - The study focuses on rising healthcare costs and the need to stop low-value medical practices, aiming to analyze randomized controlled trials (RCTs) to better understand and enhance de-implementation strategies.
- - Out of 227 eligible trials, the majority were cluster randomized and took place mainly in primary care, with many interventions directed at reducing unnecessary drug treatments and predominantly targeting physicians.
- - Findings indicate that there are significant limitations in current de-implementation research, such as high risk of bias and lack of context-specific tailoring, which may affect the reliability and applicability of the results.
Implementation of a new Digi-HTA process for digital health technologies in Finland.
Int J Technol Assess Health Care
August 2022
FinnTelemedicum, Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, Oulu, Finland.
Objectives: There has been a lack of health technology assessment (HTA) methods for novel digital health technologies (DHTs) such as mHealth, artificial intelligence, and robotics in Finland. The Digi-HTA method has been developed for this purpose. The aim of this study is to determine whether it would be possible to use Digi-HTA recommendations to support healthcare decision-makers.
View Article and Find Full Text PDFNational Development and Regional Differences in eHealth Maturity in Finnish Public Health Care: Survey Study.
JMIR Med Inform
August 2022
FinnTelemedicum, Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, Oulu, Finland.
Background: eHealth increasingly affects the delivery of health care around the world and the quest for more efficient health systems. In Finland, the development of eHealth maturity has been systematically studied since 2003, through surveys conducted every 3 years. It has also been monitored in several international studies.
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