3,188 results match your criteria: "Fibromuscular Dysplasia"

The carotid web is a rare fibromuscular dysplasia disease of the internal carotid artery wall. It is a cause of thromboembolic stroke in a demographic of patients generally younger than those with atherosclerotic carotid artery disease. It is easy to miss the diagnosis without a high index of suspicion.

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  • Renal artery stenosis (RAS) is a condition where the renal artery is narrowed by 60% or more, most commonly due to atherosclerotic plaques, affecting 5-10% of the population; rare causes include fibromuscular dysplasia and vasculitis.
  • The standard diagnostic method for RAS is digital subtraction angiography (DSA), but other imaging techniques like Doppler ultrasonography and CT angiography are also important.
  • Treatment typically involves percutaneous transluminal angioplasty (PTA), and a case study highlights a 19-year-old patient who benefitted from using a paclitaxel-coated balloon to restore renal artery function and reduce hypertension.
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  • * Postmortem examinations showed that the manatee suffered from various health issues, including aortic stenosis, left ventricular hypertrophy, and a plastic bag lodged in its esophagus, alongside cold stress symptoms.
  • * Blood tests indicated systemic inflammation and potential coagulation problems, while heart-related findings included severe cardiac abnormalities; however, the exact cause of these cardiovascular issues remains undetermined.
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  • Renal artery stenosis (RAS) and mid-aortic syndrome (MAS) are important but often overlooked causes of high blood pressure in children, with RAS involving the narrowing of renal arteries and MAS affecting the abdominal aorta and associated vessels.
  • These conditions can arise from genetic issues and other factors like fibromuscular dysplasia and Takayasu arteritis, making their symptoms complicated and hard to diagnose despite improved imaging techniques.
  • Treatment varies from medications that only partially control blood pressure to more invasive options like angioplasty and surgery, and the article emphasizes the need for a multidisciplinary approach and early detection to improve treatment outcomes for affected children.
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Carotid web, a form of fibromuscular dysplasia, involves a thin, membrane-like tissue in the carotid bulb that can cause thrombus formation and is linked to cryptogenic ischemic stroke. Diagnosis typically relies on detecting a shelf-like filling defect in digital subtraction angiography or 3D-CT angiography. We report a case of the symptomatic carotid web that could not be diagnosed using DSA or 3D-CT angiography due to a lodged thrombus but was successfully identified through carotid ultrasonography.

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Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndromes. Fibromuscular dysplasia (FMD) is an idiopathic, nonatherosclerotic, and noninflammatory arterial disease that affects small- to medium-sized arteries that can result in multifocal aneurysms, stenosis, tortuosity, and dissections. Extracoronary FMD has been identified in approximately 70% of SCAD patients and it is recommended that all SCAD patients undergo screening for FMD once in their lifetime using computed tomography angiography from head to pelvis.

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  • Spontaneous coronary artery dissection (SCAD) is a rare form of acute coronary syndrome that mainly affects young and middle-aged women, but can also occur in young men, especially those with fibromuscular dysplasia.
  • A case is presented involving a young man with fibromuscular dysplasia who experienced recurrent SCAD in the right coronary artery despite receiving conservative treatment.
  • The study emphasizes the need for more research on the underlying mechanisms of SCAD in men and the development of effective medical therapies for preventing recurrent episodes.
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The carotid web represents a specific type of fibromuscular dysplasia that primarily affects the intimal layer and is considered a high-risk factor for cryptogenic ischemic stroke. There is still debate regarding the ideal diagnostic imaging for carotid webs. Computed tomography angiography (CTA) is the preferred method in most studies; however, digital subtraction angiography (DSA) has been proven to offer great-quality images for diagnosing and evaluating the carotid web.

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  • * Symptoms and complications may differ between genders, with men experiencing more dissection and aneurysms than women.
  • * Diagnosis requires careful evaluation and imaging, while treatment typically involves monitoring and antiplatelet therapy; ongoing research is focused on understanding the genetic aspects of FMD.
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An accessory renal aneurysm in a patient with absent renal artery: a case report.

Front Cardiovasc Med

October 2024

Division of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Introduction: This study reports a patient who developed a secondary renal artery aneurysm (RAA) after occlusion of the main renal artery.

Methods: A 25-year-old woman was hospitalized due to an enlarged renal artery aneurysm (RAA). Computed tomography angiography revealed a 2.

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Current Therapy for Carotid Webs.

Ann Vasc Surg

October 2024

Vascular and Endovascular Surgery, Division Chief, Department of Vascular and Cardiothoracic Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY.

Background: Carotid webs are a potential cause of ischemic stroke, particularly in younger patients with few traditional risk factors. Despite advances in imaging technology, the management of carotid webs remains poorly defined due to its rarity, absence of evidence-based guidelines, and the unique challenges presented by these lesions. This narrative review evaluates current knowledge on carotid web management, emphasizing diagnostic features, pathophysiological considerations, and treatment strategies.

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A case report with literature review: long-term follow-up of kidney autotransplantation in fibromuscular dysplasia.

J Nephrol

October 2024

Department of Internal Medicine, Division of Nephrology, Marmara University, School of Medicine, Pendik Research and Education Hospital, Fevzi Cakmak Mah. Mimar Sinan Cd. N:41, Pendik, 34854, Istanbul, Turkey.

Article Synopsis
  • * Treatment options include antihypertensive medication, surgical revascularization, and angioplasty, with kidney autotransplantation as an alternative for complex cases.
  • * A case study of a 22-year-old woman shows successful kidney autotransplantation led to improved kidney function and controlled blood pressure, highlighting it as a viable solution for severe cases of fibromuscular dysplasia.
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  • Superior Mesenteric Artery (SMA) stenosis, often caused by atherosclerosis or thrombosis, leads to inadequate blood flow to the digestive organs, resulting in mesenteric ischemia, which can be chronic or acute.
  • This case report discusses a 66-year-old female who experienced SMA stenosis and mesenteric ischemia as a rare result of fibromuscular dysplasia (FMD).
  • The goal is to enhance awareness of mesenteric ischemia related to FMD, as there is a lack of understanding regarding its risk factors and causes.
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Multifocal Fibromuscular Dysplasia Involving the Coronary Arteries.

Radiology

October 2024

From the Department of Radiology, No 926 Hospital, Joint Logistics Support Force of the People's Liberation Army, Kaiyuan 661699, Yunnan, China.

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Spontaneous Coronary Artery Dissection Without Myocardial Infarction.

JACC Case Rep

September 2024

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.

Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute myocardial infarction. We examine 4 atypical presentations of SCAD. These cases highlight treatment course and outcomes for patients with SCAD who do not present with acute coronary syndrome.

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  • Spontaneous coronary artery dissection (SCAD) is a rare but serious condition often missed during diagnosis, highlighting the need for better recognition to decrease risks of complications.* -
  • Two case studies illustrate how advanced imaging techniques like coronary computed tomography angiography (CCTA) can effectively diagnose SCAD, which may not be evident through standard tests.* -
  • A high suspicion for SCAD is essential when traditional tests fail; further evaluations for connective tissue disorders are important, especially in low-risk patients to ensure timely treatment and better health outcomes.*
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Development of Takotsubo cardiomyopathy following spontaneous coronary artery dissection in a patient with fibromuscular dysplasia.

BMJ Case Rep

October 2024

Internal Medicine Residency, Kaiser Permanente Mid-Atlantic States, Gaithersburg, Maryland, USA.

New-onset Takotsubo cardiomyopathy following spontaneous coronary artery dissection (SCAD) is rare. We report a middle-aged woman without significant cardiovascular risk factors, who initially presented with non-ST-elevation myocardial infarction (NSTEMI) with angiography showing sudden 'pruning' of the coronary artery consistent with SCAD. One week later, the patient returned with recurrent NSTEMI.

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Background: Genome-wide association studies implicate common genetic variations in the (low-density lipoprotein receptor-related protein 1 gene) locus at risk for multiple vascular diseases and traits. However, the underlying biological mechanisms are unknown.

Methods: Fine mapping analyses included Bayesian colocalization to identify the most likely causal variant.

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Advances in the Management of Spontaneous Coronary Artery Dissection (SCAD): A Comprehensive Review.

Rev Cardiovasc Med

September 2024

Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, 10126 Torino, Italy.

Spontaneous coronary artery dissection (SCAD) is a rare but significant cause of acute coronary syndrome (ACS), primarily affecting young women, often during pregnancy. Despite its rarity, SCAD poses challenges due to limited evidence on management strategies. This review examines the current state of art of SCAD management, integrating interventional and clinical insights from recent studies.

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