100 results match your criteria: "Ferdowsi University Campus [corrected] Mashhad[Affiliation]"
Toxicol Res (Camb)
December 2024
Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Khorasan Razavi, Mashhad, Azadi Square, 9177948954, Iran.
Objective: Alzheimer's disease (ad) is a progressive and degenerative disorder of the central nervous system that is associated with cognitive and memory impairment. The main factors which have been implicated in neurodegeneration of ad are oxidative stress and cholinergic neurons dysfunction. Here, we examined the effects of auraptene, a novel acetylcholinesterase (AChE) inhibitor, on hydrogen peroxide (HO)-induced cell death in PC12 cells.
View Article and Find Full Text PDFJ Dairy Sci
December 2024
Science and Technology Park, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran; Department of Animal Science, Agricultural and Natural Resources Research and Education Center of Razavi Khorasan, Mashhad 91735-488, Iran. Electronic address:
Micronization, a dry-heat process, generates infrared electromagnetic short waves that can affect starch granules and gelatinization. A new method of corn processing, super-conditioned corn, a moisture-heat process, has potential to increase starch digestion and performance in calves. Therefore, incorporating super-conditioned or micronized corn in starter feed may enhance growth performance by improving total-tract starch digestion.
View Article and Find Full Text PDFAlthough checklists of the Iranian ladybird beetles (Coleoptera: Coccinellidae) have been made twice in recent years, they have a number of shortcomings. Moreover, since these checklist were published, several ladybird species have been added to the Iranian fauna and several previously reported have been excluded. We therefore compiled an updated checklist of Coccinellidae found in Iran and its individual provinces based on available literature and previously unpublished records.
View Article and Find Full Text PDFHealth Educ Res
December 2024
Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Shahid Bahonar Boulevard, Qazvin 34197-59811, Iran.
The use of the best teaching method to promote self-care in patients with inflammatory bowel disease (IBD) has not been well defined. Therefore, the current study was conducted to compare the effect of self-care education by two methods of teach-back and a smartphone application. The current clinical trial with a pre- and post-test design was conducted among 78 patients with IBD.
View Article and Find Full Text PDFBMC Vet Res
September 2024
Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
Background: Due to the diversity of Shiga toxin-producing Escherichia coli (STEC) isolates, detecting highly pathogenic strains in foodstuffs is challenging. Currently, reference protocols for STEC rely on the molecular detection of eae and the stx1 and/or stx2 genes, followed by the detection of serogroup-specific wzx or wzy genes related to the top 7 serogroups. However, these screening methods do not distinguish between samples in which a STEC possessing both determinants are present and those containing two or more organisms, each containing one of these genes.
View Article and Find Full Text PDFMed Oncol
July 2024
Department of Biology Sciences, Shahid Rajaee Teacher Training University, Tehran, Iran.
Exosomes play a key role in colorectal cancer (CRC) related processes. This review explores the various functions of exosomes in CRC and their potential as diagnostic markers, therapeutic targets, and drug delivery vehicles. Exosomal long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) significantly influence CRC progression.
View Article and Find Full Text PDFProbiotics Antimicrob Proteins
July 2024
Department of Food Safety and Quality Control, Research Institute of Food Science and Technology (RIFST), Mashhad, Iran.
Listeria monocytogenes is a notable food-borne pathogen that has the ability to create biofilms on different food processing surfaces, making it more resilient to disinfectants and posing a greater risk to human health. This study assessed melittin peptide's anti-biofilm and anti-pathogenicity effects on L. monocytogenes ATCC 19115.
View Article and Find Full Text PDFFoods
May 2024
Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Davutpasa Campüs, Istanbul 34210, Türkiye.
Sourdough fermentation is one of the oldest traditional methods in food technology and occurs as a result of fermentation of flour prepared from grains. The nutritional role of sourdough is related to the final composition of fermented foods prepared through sourdough fermentation, and recently, sourdough has become an important application to improve nutrition characteristics of bread. Thanks to lactic acid bacteria (LAB) presented in sourdough microflora and metabolites partially produced by yeasts, technological and important nutritional features of the bread improve and an increase in shelf life is achieved.
View Article and Find Full Text PDFIntegr Environ Assess Manag
September 2024
Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Effective resource allocation in the agri-food sector is essential in mitigating environmental impacts and moving toward circular food supply chains. The potential of integrating life cycle assessment (LCA) with machine learning has been highlighted in recent studies. This hybrid framework is valuable not only for assessing food supply chains but also for improving them toward a more sustainable system.
View Article and Find Full Text PDFNat Plants
June 2024
PHIM Plant Health Institute, Univ. Montpellier, INRAE, CIRAD, Institut Agro, IRD, Montpellier, France.
Blast disease caused by the fungus Magnaporthe oryzae is one of the most devastating rice diseases. Disease resistance genes such as Pi-ta or Pi-ta2 are critical in protecting rice production from blast. Published work reports that Pi-ta codes for a nucleotide-binding and leucine-rich repeat domain protein (NLR) that recognizes the fungal protease-like effector AVR-Pita by direct binding.
View Article and Find Full Text PDFNat Plants
May 2024
Environmental Sciences and Engineering, Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia.
Bioresour Bioprocess
July 2023
Department of Chemical Engineering, Ferdowsi University of Mashhad, Azadi Square, Pardis Campus, 91779-48944, Mashhad, Iran.
In this study, the sequential extraction of the three types of biochemicals from microalgae is employed, which is a more realistic and practical solution for large-scale extraction of bioproducts. The drying, grinding, organic solvent treatment, and ultra-sonication were combined to disrupt cells and sequentially extract bioproducts from three microalgae strains, Chlorella sorokiniana IG-W-96, Chlorella sp. PG-96, and Chlorella vulgaris IG-R-96.
View Article and Find Full Text PDFNat Plants
May 2024
Environmental Sciences and Engineering, Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia.
Perennial plants create productive and biodiverse hotspots, known as fertile islands, beneath their canopies. These hotspots largely determine the structure and functioning of drylands worldwide. Despite their ubiquity, the factors controlling fertile islands under conditions of contrasting grazing by livestock, the most prevalent land use in drylands, remain virtually unknown.
View Article and Find Full Text PDFComput Biol Med
April 2024
Department of Computer Engineering, Faculty of Engineering and Natural Sciences, Kadir Has University, Istanbul, Turkey; Future Technology Research Center, National Yunlin University of Science and Technology, Douliou, Yunlin, 64002, Taiwan. Electronic address:
Healthcare has significantly contributed to the well-being of individuals around the globe; nevertheless, further benefits could be derived from a more streamlined healthcare system without incurring additional costs. Recently, the main attributes of cloud computing, such as on-demand service, high scalability, and virtualization, have brought many benefits across many areas, especially in medical services. It is considered an important element in healthcare services, enhancing the performance and efficacy of the services.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2023
Catalonia Institute for Energy Research─IREC, Sant Adrià del Besòs 08930, Barcelona, Spain.
J Neurovirol
October 2023
Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch, Ferdowsi University Campus, Azadi-Square, Mashhad, 9177949367, Iran.
Sci Rep
October 2023
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
J Neurovirol
August 2023
Immunology Research Center, Inflammation and Inflammatory Diseases Division, Mashhad University of Medical Sciences, Mashhad, Iran.
There is an urgent need to find an effective therapy for life-threatening HTLV-1-associated diseases. Bitter melon (Momordica charantia) is considered a traditional herb with antiviral and anticancer properties and was tested in this study on HTLV-1 infectivity. GC-MS analyzed the alcoholic extract.
View Article and Find Full Text PDFFront Aging Neurosci
July 2023
Department of Health Promotion and Rehabilitation, Lithuanian Sports University, Kaunas, Lithuania.
Background: The world's population is aging, but life expectancy has risen more than healthy life expectancy (HALE). With respect to brain and cognition, the prevalence of neurodegenerative disorders increases with age, affecting health and quality of life, and imposing significant healthcare costs. Although the effects of physical exercise on cognition in advanced age have been widely explored, in-depth fundamental knowledge of the underlying mechanisms of the exercise-induced cognitive improvements is lacking.
View Article and Find Full Text PDFBioTech (Basel)
July 2023
Centre for Water, Energy and Waste, Harry Butler Institute, Murdoch University, Murdoch 6150, Australia.
Microalgae can treat waste streams containing elevated levels of organic carbon and nitrogen. This process can be economically attractive if high value products are created simultaneously from the relatively low-cost waste stream. Co-production of two high value microalgal products, phycocyanin and polyhydroxybutyrate (PHB), was investigated using non-axenic MUR126 and supplemental organic carbon (acetate, oxalate, glycerol and combinations).
View Article and Find Full Text PDFTrials
June 2023
Metabolic Syndrome Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran.
Background: Different dietary protein sources are supposed to have various effects on metabolic responses and arterial stiffness in the postprandial period. This study aims to assess the postprandial effects of dietary protein sources, including animal-based protein (AP) and plant-based protein (PP), as part of a high-protein breakfast on appetite response, energy metabolism, and arterial stiffness in overweight and obese men.
Methods: This acute randomized crossover clinical trial will be conducted at the Persian study research center at Imam Reza Hospital, affiliated with the Mashhad University of Medical Sciences, located in the northeast of Iran.
J Oral Biol Craniofac Res
April 2023
Department of Anatomy and Cell Biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Objectives: Recent investigations indicate that canine periodontal ligament-derived stem cells (cPDLSCs) may reveal a reliable strategy for repair of periodontal tissues via cell-based tissue engineering approaches Due to limited research, his study aimed to demonstrate the phenotypic characterization of cPDLSc in comparison with canine bone marrow-derived mesenchymal stem cells (cBMSCs)
Methods: Mesenchymal stem cells (MSCs) were obtained from PDL and BM of five male adult Mongrel dogs. isolation and expansion as well as biologic characterization including colony unit formation (CFU), osteogenic and adipogenic differentiation, flow cytometric analysis of CD34 and CD44, and RT-PCR of alkaline phosphatase (ALP), osteocalcin (OCN), periostin (POSTN) and S100A4 were performed. Furthermore, electron microscopy analysis was done to complement the comparative research.
J Educ Health Promot
February 2023
Department of Vital Statistics, School of Public Health, Mashhad University of Medical Sciences, Mashhad, Iran.
Background: Gestational diabetes is the most common medical complication and a common metabolic disorder during pregnancy. Increasing people's self-efficacy is one of the best ways to control this disease. As there is a lag of intervention in this regard, the purpose of this study was to determine the effect of couple supportive counseling on self-efficacy in women with insulin-treated gestational diabetes.
View Article and Find Full Text PDFJ Funct Biomater
January 2023
Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad 91778, Iran.
Among scaffolds used in tissue engineering, natural biomaterials such as plant-based materials show a crucial role in cellular function due to their biocompatibility and chemical indicators. Because of environmentally friendly behavior and safety, green methods are so important in designing scaffolds. A key bioactive flavonoid of the plant, Icariin (ICRN), has a broad range of applications in improving scaffolds as a constant and non-immunogenic material, and in stimulating the cell growth, differentiation of chondrocytes as well as differentiation of embryonic stem cells towards cardiomyocytes.
View Article and Find Full Text PDFAppl Biochem Biotechnol
March 2023
Inflammation and Inflammatory Diseases Division, Medical Campus, Immunology Research Center, Mashhad University of Medical Sciences, Azadi Square, Mashhad, 9177948564, Iran.
Human T-cell leukaemia virus type 1 (HTLV-1) is the causative agent of two life-threatening diseases, adult T cell leukaemia/lymphoma (ATLL), and HTLV-1-associated myelopathy/tropical spastic (HAM/TSP). HTLV-1 protease (HTLV-1-PR) is an aspartic protease that represents a promising target for therapeutic purposes like human immunodeficiency virus-PR inhibitors (HIV-PR). Therefore, in this study, the human Fc fusion recombinant-PR (HTLV-1-PR:hFcγ1) was designed and expressed for two applications, finding a blocking substrate as a potential therapeutic or a potential subunit peptide vaccine.
View Article and Find Full Text PDF