Physical fitness assessment tools for children with developmental coordination disorder and their feasibility for low-income settings: A systematic review.

Background: This study systematically reviewed the literature on physical fitness assessment tools for children with developmental coordination disorder compared with typically developing children aged 7 to 10 and analyzed the feasibility of these tools for use in low-income settings.

Methods: Searches were conducted in the PubMed, Scopus, Web of Science, and EBSCO/RIC databases. The Newcastle - Ottawa Quality Assessment Scale assessed the methodological quality of the studies, and a checklist adapted from COSMIN assessed the feasibility of the instruments.

Bayesian spatio-temporal modeling of severe acute respiratory syndrome in Brazil: A comparative analysis across pre-, during, and post-COVID-19 eras.

This paper presents an investigation into the spatio-temporal dynamics of Severe Acute Respiratory Syndrome (SARS) across the diverse health regions of Brazil from 2016 to 2024. Leveraging extensive datasets that include SARS cases, climate data, hospitalization records, and COVID-19 vaccination information, our study employs a Bayesian spatio-temporal generalized linear model to capture the intricate dependencies inherent in the dataset. The analysis reveals significant variations in the incidence of SARS cases over time, particularly during and between the distinct eras of pre-COVID-19, during, and post-COVID-19.

Insights into host-pathogen interaction based on the comparison of genomes of isolated from dogs, humans, and a rodent in the same epidemiological context: A one health approach.

Leptospirosis is a zoonotic infectious disease that significantly impacts animal and public health. Comparative genomics can aid in understanding poorly understood aspects of leptospirosis pathogenesis, including infection mechanisms, antimicrobial resistance, and host interactions across different epidemiological scenarios. This study aimed to compare the genomes of serogroup Icterohaemorrhagiae strains isolated from three host species in a single epidemiological scenario.

Arbovirus exposure and subclinical myocardial dysfunction in an Indigenous population in Northeast Brazil: a cross-sectional study.

Background: Human activities, such as urbanization and climate change, have facilitated the spread of arbovirus-carrying vectors, disproportionately affecting vulnerable traditional Indigenous communities.

Objective: To explore the relationships between subclinical myocardial dysfunction, assessed by global longitudinal strain (GLS), and comprehensive arbovirus serology in an Indigenous population, while also describing the serological and epidemiological profile of dengue, chikungunya, and Zika viruses.

Methods: This ancillary study is part of the first phase (2016-2017) of the Project of Atherosclerosis among Indigenous Populations (PAI), a cross-sectional study involving participants from two Indigenous communities with different degrees of urbanization and a highly urbanized city in Northeast Brazil.

Effect of listening to music on anxiety, pain, and cardiorespiratory parameters in cardiac surgery: A randomized clinical trial.

Purpose: To evaluate the effect of listening to music on preoperative anxiety, postoperative pain (at rest and during coughing), and cardiorespiratory parameters in patients undergoing cardiac surgery.

Design: Single-centered, randomized, parallel, superiority clinical trial.

Methods: This study was carried out with 50 adult patients undergoing elective cardiac surgery randomly allocated at a 1:1 ratio to one of the groups, experimental (n = 25) or control (n = 25).

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Induced by Cigarette Smoke in Humans: A Systematic Review.

The present systematic review aims to put together human population studies that include some relationship between genetic polymorphisms and genotoxicity as well as to evaluate the quality of the published studies induced by cigarette smoke exposure in vivo. The present systematic review was built according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. Different genotoxicity assays were used by different authors, although the major goal was the genotoxicity assessment by means of micronucleus, comet, sister chromatid exchange, and chromosomal aberration assays.

Discovering the allure of forests: Exploring adolescent queries in nature-rich environments.

This study explores adolescents' inherent curiosity about nature through the production of self-generated questions during a field visit to a nature-rich environment, followed by descriptive-interpretative analysis using focus groups. Utilizing cultural probes and content-free question tokens, we collected 164 valid questions produced by 36 adolescents during the field session. Biotic elements, like species, turned out to be more intriguing than abiotic elements, originating 89.

Small and medium-scale biorefineries: biomass quantification and its bioeconomic potential in the Southern Coastal Territory of Bahia.

Small and medium-scale biorefineries are processing facilities designed to produce a portfolio of value-added products with applications in different productive sectors. The Territory of the Southern Coast (TSC) of Bahia in Brazil has a high potential to provide agricultural and forest biomass for these bioindustries. This study focuses on quantifying the biomass of key agricultural crops in the TSC from 1999 to 2019, utilizing data from the Municipal Agricultural Production (MAP) survey conducted by the Brazilian Institute of Geography and Statistics (IBGE).

Orthodontic retainers: are they all the same?

Introduction: It is known that the stability of the results obtained with orthodontic treatment depends, in addition to the functional and aesthetic aspects, also on the adequate planning of the retention devices, the patient's compliance with this new phase, and the physiological changes that the human body experiences over the years, throughout the craniofacial aging process.

Objective: This article discusses the importance of the orthodontic retention phase and the influence of diagnosis, planning and execution of corrective treatment of malocclusions, in order to achieve the expected success.

Methods: Throughout the text, different types of retainers and approaches during this phase will be presented, with the aim of ensuring the stability of the results obtained after correcting problems in the vertical, transverse and anteroposterior directions.

Rotational flap versus long plantar flap for transmetatarsal amputation closure following revascularization.

Objective: The integrity of the plantar flap is important for transmetatarsal amputation (TMA) classic closure. However, in ischemic wounds, the plantar flap can be compromised, making the TMA coverage difficult. The aim of this study was to compare the outcomes of rotational vs long plantar flaps for transmetatarsal amputation closure in patients with dysvascular partial foot amputations.

Monkeypox: Oral manifestation as diagnostic indicator.

Lesions of monkeypox affect the oral mucosa in approximately 70% of infected patients and reported as the first clinical sign of the disease, manifesting as macules, papules, vesicles, or blisters, which are highly contagious and are followed by the appearance of lesions on the face and extremities of the body. These lesions have clinical aspects like recurrent herpes simplex, herpes zoster, and secondary syphilis and should be part of differential diagnoses. The clinical course after initial oral manifestation is shown to support the clinical diagnosis.

Multidisciplinary nursing care in chronic Chagas disease: a scoping review.

Background: Nurses provide essential care for symptomatic chronic Chagas disease carriers, caused by Trypanosoma cruzi, offering crucial support, symptom management, medication administration, and monitoring to enhance their health-related quality of life.

Objective: To increase healthcare professionals' awareness of the critical role played by high-quality care in the management of patients with chronic Chagas disease.

Methods: This scoping review employed the PRISMA-ScR method as a framework for article selection.

Interventions in the Sexuality of Men With Stomas: A Scoping Review.

Aims: To map interventions in the sexuality of men with stomas.

Design: Scoping review, following JBI and PRISMA-ScR guidelines to report results.

Methods: Databases consulted were PubMed, via National Library of Medicine, Latin American and Caribbean Health Sciences Literature, Web of Science, Scopus, Embase, Scientific Electronic Library Online, Brazilian Electronic Library of Thesis and Dissertations, CAPES Catalogue of Thesis and Dissertations and Open Access Scientific Repository of Portugal.

Machine learning prediction model for oral mucositis risk in head and neck radiotherapy: a preliminary study.

Purpose: Oral mucositis (OM) reflects a complex interplay of several risk factors. Machine learning (ML) is a promising frontier in science, capable of processing dense information. This study aims to assess the performance of ML in predicting OM risk in patients undergoing head and neck radiotherapy.

McGrath MAC Versus Three-Dimensional Printed Video Laryngoscopes: A Randomized, Manikin-Simulated Noninferiority Controlled Study with Medical Students.

Background: Proficiency in endotracheal intubation (ETI) is essential for medical professionals and its training should start at medical schools; however, large caseload may be required before achieving an acceptable success rate with direct laryngoscopy. Video laryngoscopy has proven to be an easier alternative for intubation with a faster learning curve, but its availability in medical training may be an issue due to its high market prices. We devised a low-cost 3-dimensionally printed video laryngoscope (3DVL) and performed a randomized trial to evaluate if the intubation success rate on the first attempt with this device is noninferior to a standard commercially available video laryngoscope (STVL).

4D-DIA Proteomics Uncovers New Insights into Host Salivary Response Following SARS-CoV-2 Omicron Infection.

Since late 2021, Omicron variants have dominated the epidemiological scenario as the most successful severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sublineages, driving new and breakthrough infections globally over the past two years. In this study, we investigated for the first time the host salivary response of COVID-19 patients infected with Omicron variants (BA.1, BA.

Association between Congenital Zika Syndrome and hospitalizations during early childhood: a nationwide cohort study.

Background Congenital Zika Syndrome (CZS) has been linked to a wide spectrum of abnormalities. However, differences in hospitalization patterns between children with and without CZS have not yet been investigated. Methods We compared rates of hospital admissions for all and specific diseases, proportions of admission causes, and total length of hospital stay (LOS) between children with CZS and those without the syndrome.

Time-of-day effects on physical performance and perceptual responses in Brazilian Jiu-Jitsu athletes.

This study investigated how the time of day affects physical performance and perceptual responses in Brazilian Jiu-Jitsu (BJJ) athletes. Given the significance of circadian rhythms on athletic capabilities, we aimed to determine whether performance variations occur across different times of the day (morning, 10:00-11:00h; afternoon, 14:00-15:00h; and evening, 18:00-19:00h) and if these effects differ by sex. In total, 23 BJJ athletes (9 females, 14 males) participated in this study.

Ethnic disparities in survival and progression among EGFR-mutated adenocarcinoma of lung cancer patients treated with tyrosine kinase inhibitors: a systematic review and meta-analysis.

Background: The benefit of treatment with tyrosine kinase inhibitors targeting the epidermal growth factor receptor (EGFR-TKI) for lung adenocarcinoma (ADC), stratified by ethnicity, has not yet been fully elucidated.

Methods: We searched PubMed, Embase, and Cochrane databases for studies that investigated EGFR-TKI for lung ADC. We computed hazard ratios (HRs) or risk ratios (RRs) for binary endpoints, with 95% confidence intervals (CIs).

Development of a Population Pharmacokinetic Model Characterizing the Tissue Distribution of Resveratrol After Administration by Different Routes and Doses in Rats.

Studies have demonstrated that resveratrol exerts several pharmacological effects. However, the pharmacokinetic parameters are not completely established. This study describes the plasma pharmacokinetics and tissue distribution of resveratrol after administration by different routes and doses in rats.

Agathisflavone Inhibits Viability and Modulates the Expression of miR-125b, miR-155, IL-6, and Arginase in Glioblastoma Cells and Microglia/Macrophage Activation.

Glioblastomas (GBM) are malignant tumours with poor prognosis. Treatment involves chemotherapy and/or radiotherapy; however, there is currently no standard treatment for recurrence, and prognosis remains unfavourable. Inflammatory mediators and microRNAs (miRNAs) influence the aggressiveness of GBM, being involved in the communication with the cells of the tumour parenchyma, including microglia/macrophages, and maintaining an immunosuppressive microenvironment.

Characteristics of sensory processing changes in children with developmental coordination disorder: A systematic review.

Background: Sensory processing difficulties are common in neurodevelopment conditions, such as developmental coordination disorder (DCD), and can significantly impact daily living activities.

Aims: To systematically review the literature to (1) synthesize the characteristics (sections and patterns) of sensory processing alterations in children with developmental coordination disorder (DCD), (2) compare these characteristics with those of children with typical development or associated comorbidities, and (3) identify which characteristics may be present from early childhood.

Methods: This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and was submitted and registered in PROSPERO.

biofilms: implications for survival, transmission, and disease management.

Leptospirosis is a zoonotic disease caused by bacteria, affecting humans and a broad range of wild and domestic animals in diverse epidemiological settings (rural, urban, and wild). The disease's pathogenesis and epidemiology are complex networks not fully elucidated. Epidemiology reflects the One Health integrated approach of environment-animal-human interaction, causing severe illness in humans and animals, with consequent public health burdens.

Pterional vs. mini-pterional craniotomy for intracranial aneurysms: a systematic review and meta-analysis.

The mini-pterional craniotomy (mPT) was designed to be a minimally invasive alternative to the standard pterional (PT) approach. However, it remains unclear which technique produces better results. Thus, we aimed to perform a meta-analysis comparing functional, surgical, and aesthetic outcomes between mPT and PT in intracranial aneurysms.