3,397 results match your criteria: "Federal University of Santa Maria.[Affiliation]"

Background: The efficacy and safety of P2Y12 inhibitors (P2Y12i) with aspirin in patients with non-cardioembolic ischemic cerebrovascular events remains a topic of ongoing debate. Therefore, we conducted an updated meta-analysis to compare these drugs with aspirin alone.

Methods: We systematically searched PubMed, Embase, and Cochrane Central for randomized controlled trials (RCTs) comparing the two treatment regimens in patients with ischemic cerebrovascular events.

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Orofacial pain is one of the most common causes of chronic pain leading to physical and cognitive disability. Several clinical and pre-clinical studies suggest that chronic pain results in cognitive impairment. However, there is a lack of meta-analyses examining the effects of orofacial pain models on behavioral learning and memory in rodents.

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Objectives: This in vitro study aimed to investigate the toothbrushing wear on both enamel and dentin surfaces of reference and commercially available dentifrices.

Methods: Bovine enamel and dentin blocks were initially polished and embedded within a resin composite in square shapes (10×8×6 mm3). Employing toothbrushes equipped with nylon bristles, a toothbrushing machine was utilized, subjecting dentin specimens (n = 36) to 500 brush cycles and enamel samples to 5000 brush cycles (n = 36).

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Unlabelled: The FRAX® algorithm showed good accuracy in women living with DM followed in primary care. There were no differences between the ROC curve with and without adjustments for major and hip fractures. The FRAX® 10-year and FRAX® AR were better calibrated in this population.

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This paper presented the preparation, characterization, and adsorption properties of Brazil nut shell activated carbon for catechol removal from aqueous solutions. The equilibrium adsorption of catechol molecules on this activated was experimentally quantified at pH 6 and temperatures ranging from 25 to 55 °C, and at 25 °C and pH ranging from 6 to 10. These results were utilized to elucidate the role of surface functionalities through statistical physics calculations.

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Objectives: The aim of this study was to adapt and apply the Portuguese version of the Transgender Man Voice Questionnaire in a sample of Brazilian transgender men and to investigate the relationship between voice satisfaction and hormone therapy duration. In addition, we suggest reducing and reformulating the questionnaire for screening.

Methods: We conducted a cross-sectional study of 31 transgender men aged 18-50 years undergoing hormone therapy who answered a questionnaire adapted from the Transgender Woman Voice Questionnaire, validated in Portuguese.

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Objective:  In recent years, the management of placenta accreta spectrum (PAS) has fallen into two categories: planned hysterectomy and conservative management to preserve fertility. However, optimal management remains unclear. Therefore, we conducted a systematic review and meta-analysis comparing the two to evaluate which approach was associated with lower surgical morbidity.

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Lignocellulosic waste, like corn stover (CS), is widely produced and serves as a key feedstock for biofuels and biochemicals. Semi-continuous subcritical water hydrolysis (SWH) is an eco-friendly method that breaks down cellulose and hemicellulose bonds. To boost fermentable sugar (FS) yields, steam explosion (SE) pretreatment was tested on CS, achieving a cellulose content of 74.

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In cells, the term "cellular aging" represents a collection of biological changes that can precede the proliferative senescence states. Cells more resistant to proliferative senescence, such as the ones found in the basal layer of the epidermis, may also exhibit these aging patterns. Therefore, cellular aging events could be induced by endogenous signals named here as cellular aging triggers (CATs) components.

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Bipolar disorder (BD) is a central nervous system condition that is typified by fluctuations in mood, oscillating between depressive and manic, and/or hypomanic episodes. The objective of this study was to test the hypothesis that strength training may act as a potent protector against behavioral and neurochemical changes induced by BD. A strength training protocol was performed with adult male Wistar rats, and seven days following the conclusion of training, a single ouabain injection was administered.

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Rice is considered to be moderately salt-tolerant during germination, development, and ripening stages, and environmentally sensitive during seedling and reproductive stages, which affects seedling emergence and growth, resulting in significant yield losses. Seed conditioning with chitosan has been employed as a useful tool in high-salinity environments with the aim of increasing crop productivity and quality, as well as promoting more sustainable agricultural practices. Therefore, this study aimed to examine the effect of seed conditioning with chitosan on seed germination and rice seedling growth under salinity stress.

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Hypothyroidism is known to affect memory consolidation, and our prior research highlighted the potential of chrysin as a therapeutic agent to restore cognitive function. The present study aimed to investigate the action mechanism of chrysin on memory deficits in hypothyroid in C57BL/6 female mice. We assessed cognitive flexibility, declarative, working, and aversive memories while analyzing the BDNF/TrkB/AKT/Creb neuroplasticity signaling pathway and synaptic function in the hippocampus and prefrontal cortex.

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The effects of exercise on anxiety and depression in adults with cancer: A meta-review of meta-analyses.

J Psychosoc Oncol

December 2024

Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Australia.

Background: This meta-review aimed to synthesize the evidence of the effects of exercise on anxiety and depression symptoms amongst adults with cancer, and cancer-survivors, comparing effects sizes between meta-analysis.

Methods: Major databases were searched up to February 9, 2024 for meta-analyses evaluating the effects of exercise, using anxiety and/or depression scales. Effect size (ES) values were calculated as standardized differences in the means and expressed as the Standardized Mean Difference (SMD) with the 95% confidence interval (95%CI).

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Background: The present study investigated the effects of high CO partial pressures (pCO) in dynamic controlled atmosphere monitored by respiratory quotient (DCA-RQ 1.3) on the anaerobic metabolism compounds, physiological disorders and overall quality of 'Maxi Gala' apples after 9 months of storage (2.0 °C), plus 7 days of shelf life (20 °C).

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Chronic carbendazim exposure disrupts behavioral responses and redox-regulatory mechanisms in non-target detritivore Nauphoeta cinerea nymphs.

Environ Toxicol Pharmacol

December 2024

Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Carbendazim is widely applied in agriculture to control various fungal diseases during pre-harvest and post-harvest processes owing to its efficacy and cost-effectiveness. However, environmental and food contamination by carbendazim has become a global health issue. Indeed, the declining biodiversity of beneficial insects owing to agricultural intensification is currently of keen concern to the scientific community.

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Toxicity assessment of effluent from a potato-processing industry in Cyprinus carpio.

Environ Toxicol Pharmacol

December 2024

Environmental Engineering Laboratory, Department of Sanitary and Environmental Engineering, Federal University of Santa Maria (UFSM), Avenida Roraima, 1000, Santa Maria, RS 97015-900, Brazil.

Potato (Solanum tuberosum) cultivation faces the challenge of excessive pesticide use. During processing, the disposal of large volumes of contaminated water into water bodies can result in severe environmental damage, such as fish deaths. This study aimed to evaluate the toxicological effects of chemical compounds present in the effluent from a potato-processing industry using the test organism Cyprinus carpio.

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This study evaluated the effect of grinding and finishing treatments (polishing or glaze) on the color stability, translucency and opalescence of a translucent zirconia (3Y-TZP) after immersion in red wine. Discs (Ø= 12 mm; thickness 0.8 mm) of 3Y-TZP (Zenostar T, Ivoclar AG) were randomly allocated (n= 8) according to the surface treatment factor: Ctrl - as-sintered; Gr - grinding with diamond bur #4219; Gr + Pol - grinding followed by polishing; Gr + Gl - grinding followed by glaze.

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The aim of this study is to assess the presence of MDP at various stages of the bonding procedure, enhance the adhesive and mechanical behavior of cemented zirconia ceramics. Fifty ceramic slices (15 × 15 × 2 mm) and 48 discs (Ø= 10 mm, 1 mm thickness) were prepared, sintered, air-abraded with aluminum oxide, and allocated considering: 1) microshear bond strength (µSBS) between ceramic slices and luting agent cylinders (height= 1 mm, Ø= 1.2 mm); 2) fatigue behavior, ceramic discs paired and bonded onto fiber-epoxy resin discs (Ø= 10 mm, 2.

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The Influence of Blood Titanium Levels on DNA Damage in Brazilian Workers Occupationally Exposed to Different Chemical Agents.

Biol Trace Elem Res

December 2024

Laboratory of Toxicology (LATOX), Department of Analysis, Faculty of Pharmacy, Federal University of Rio Grande do Sul, Rua São Luis 150-Anexo II, Santa Cecília, Porto Alegre, RS, CEP: 90610-000, Brazil.

Occupational exposure to pollutants may cause health-damaging effects in humans. Genotoxicity assays can be used to detect the toxic effects of pollutants. In the present study, we evaluated genetic damage in three populations occupationally exposed to benzene, pyrenes, and agrochemicals and assessed the possible influence of titanium (Ti) co-exposure.

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This study aimed to analyze yield components and maize yield cultivated at different population densities in management zones (MZs) delimited based on mapping the spatial variability of the soil's apparent electrical conductivity (ECa). The soil ECa was measured, and two MZs were subsequently delimited, one with low ECa and the other with high ECa. In each MZ, four maize sowing densities were tested: 60,000 (D1); 80,000 (D2); 100,000 (D3); and 140,000 (D4) seeds ha.

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Protein and Oil Contents, Micro- and Macronutrients, and Other Quality Indicators of Soybean Cultivated in Lowland Fields.

Foods

November 2024

Laboratory of Agroindustrial Processes Engineering (LAPE), Federal University of Santa Maria, 3013 Taufik Germano Rd., Universitário II DC, Cachoeira do Sul 96503-205, Brazil.

The cultivation of soybean is being expanded in traditional areas cultivated with rice, called the lowlands. However, soil characteristics are different from those in the highlands, which influences the exportation of nutrients to the grains. Therefore, this study aimed to determine the physical-chemical and technological characteristics of soybean grains harvested in lowlands in Brazil.

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Effects of postoperative hyperbaric oxygen therapy on hematological and biochemical parameters in patients diagnoses with pyometra in sepsis.

Top Companion Anim Med

December 2024

Graduate Program in Veterinary Medicine, Federal University of Santa Maria, University Veterinary Hospital, CEP, Camobi Av. Roraima - 1000, building 97, room 126 97105-900, Santa Maria-RS, Brazil.

The aim of this study was to evaluate the impact of hyperbaric oxygen therapy (HBOT) on hematologic and biochemical markers in dogs with pyometra in sepsis. Eighteen patients were equally distributed between the control group (CG) and the hyperbaric group (HG). All patients underwent ovariohysterectomy, supportive therapy, and insertion of a central venous catheter.

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This study aimed to investigate the photobiological action of cocoa solution on a human fibroblast cell line (HFF-1) exposed to ultraviolet B (UVB) radiation. Three experimental models were utilized, where fibroblast cells were treated with different concentrations of cocoa as follows: 50; 100; 250; 500; 750; 1000 or 1500 µg/ml and concomitantly exposed to UVB 7 kJ/m for 10 min. The following parameters were examined 1) analysis of the pre-treatment action of cocoa; 2) investigation of the co-treatment activity of cocoa at the time of exposure; and 3) study the effect of cocoa in the post-treatment of the damage initiated by UVB.

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Pythiosis, caused by Pythium insidiosum, is an infectious and non-transmissible disease affecting horses, dogs, and humans, with no effective drug treatment available. Triazoles are compounds of interest for their potential pharmacological properties against fungi and bacteria. In this study, we synthesized three new triazole compounds (C1, C2, and C3) to assess their in vitro activities against P.

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Article Synopsis
  • Aspergillus westerdijkiae, known as 'golden mould,' can grow on dry-cured meats and produce the harmful mycotoxin ochratoxin A, posing health risks to humans.
  • The study explored how different temperatures (15, 20, and 25 °C) and water activity levels (0.85 to 0.99) affect the growth and ochratoxin production of two A. westerdijkiae strains over 28 days.
  • Optimal growth occurred at 20-25 °C and high water activity, while strain S1 produced the most ochratoxin A at certain conditions, indicating that even under ideal growth, mycotoxin production can be significant, highlighting the need for better
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