6 results match your criteria: "Federal University of Rio de Janeiro - UNIRIO[Affiliation]"

A Pharmacogenomics-Based In Silico Investigation of Opioid Prescribing in Post-operative Spine Pain Management and Personalized Therapy.

Cell Mol Neurobiol

May 2024

Department of Orthopaedic Surgery & Sports Medicine, Director of Musculoskeletal Services Bassett Healthcare Network 1 Atwell Road, Cooperstown, NY, 13326, USA.

Considering the variability in individual responses to opioids and the growing concerns about opioid addiction, prescribing opioids for postoperative pain management after spine surgery presents significant challenges. Therefore, this study undertook a novel pharmacogenomics-based in silico investigation of FDA-approved opioid medications. The DrugBank database was employed to identify all FDA-approved opioids.

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Article Synopsis
  • - This study aims to clarify the prevalence and severity of atopic dermatitis (AD) in adults across various regions, including Asia, Eurasia, and Latin America, revealing significant gaps in current understanding.
  • - An international web-based survey collected data from multiple countries, finding AD prevalence varies from 3.4% in Israel to 33.7% in Thailand, often higher in females, with mild and moderate cases being more common than severe cases.
  • - Results indicate that AD is a significant health concern in adults, challenging the notion that it predominantly affects children, as many respondents experience chronicity and high morbidity related to the condition.
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This paper investigated the effects over time of different forms of neuromuscular training on hemodynamic responses, the estimated VO, and walking performance. 105 older adults were randomly organized into three groups: RG, RG, and the Control Group (CG). RG and RG did 4 weeks of adaptation phase training and 12 weeks of intervention with different loads: moderate loads for RG.

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Infectious diseases are serious public health problems, affecting a large portion of the world's population. A molecule that plays a key role in pathogenic organisms is trehalose and recently has been an interest in the metabolism of this molecule for drug development. The trehalose-6-phosphate synthase (TPS1) is an enzyme responsible for the biosynthesis of trehalose-6-phosphate (T6P) in the TPS1/TPS2 pathway, which results in the formation of trehalose.

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Cancer prevention campaigns and Internet access: promoting health or disease?

J Epidemiol Community Health

October 2008

Federal University of Rio de Janeiro-UNIRIO, Rua das Laranjeiras 91/1202, CEP 22240-000, Rio de Janeiro, Brazil.

Background: The Internet has become the most popular source of reference on health-related issues. However, little has been invested in studies that use it as a tool to evaluate health-related cultural events as cancer prevention campaigns.

Aims: To correlate audience patterns on the web pages of a Brazilian Ministry of Health (MOH) cancer institute (http://www.

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