Qualitative chemical characterization of salva-de-marajó (Lippia origanoides, Verbenaceae) preparations.

Lippia origanoides Kunth (LO, Verbenaceae), commonly known in Brazil as salva-de-marajó, is an aromatic plant native to the Americas. Quilombola women from Oriximiná (Pará State, Brazil) use decoctions and decoction vapors of LO aerial parts orally or in sitz baths to alleviate symptoms of dysmenorrhea. This study aimed to evaluate LO decoctions and essential oils through a chemo-qualitative approach.

A comparison between community and treatment-seeking samples of hoarding disorder.

Objective: Hoarding disorder studies are primarily based on persons who seek treatment and demonstrate good insight. The aim of the present study is to evaluate whether there are differences between community and treatment-seeking samples of individuals with hoarding disorder (HD).

Methods: Fourteen people with HD from the community and twenty treatment-seeking people with HD were assessed by a battery of instruments to evaluate HD features and other associated characteristics.

Corrigendum to "Epidemiology of adult patients with atopic dermatitis in AWARE 1: A second international survey" [World Allergy Organ J 16 (3) (2023) 100724].

[This corrects the article DOI: 10.1016/j.waojou.

Can we effectively manage binge eating disorder with pharmacotherapy?

Introduction: Pharmacological and other treatments for binge eating disorder (BED) predate its inclusion as the third main eating disorder in the 2013 DSM-5. Currently, second in line to psychological therapy are psychotropics such as antidepressants, anticonvulsants and stimulants.

Areas Covered: This review summarizes the evidence and emerging evidence on the pharmacotherapies for BED and their potential for wider use.

Warfarin and Aspirin Versus Warfarin Alone in Patients With HeartMate 3 Left Ventricular Assist Device: A Systematic Review and Meta-Analysis.

Background And Aims: HeartMate 3 (HM3), a fully magnetically levitated ventricular assist device (LVAD), has been associated with reduced thromboembolic events compared to HeartMate II. However, bleeding events remained significant. Among patients undergoing HM3 implantation, the standard antithrombotic regimen comprises both warfarin and aspirin (ASA), but there is a lack of evidence on the optimum antithrombotic therapy.

Antitumoral effect thought ROS production of the sesquiterpene lactone centratherin isolated from , an endemic plant from Brazil.

Cancer is a global public health problem, requiring the development of new and more effective drugs for treatment. , is a common plant found in the Brazilian Cerrado and Atlantic Forest and is used as a traditional medicinal plant in some regions. This study evaluated the potential antitumor effect of centratherin, a compound isolated from leaves, against cancer cells.

Capturing spontaneous interactivity: a multi-measure approach to analyzing the dynamics of interpersonal coordination in dance improvisation.

Introduction: Interpersonal coordination is widely acknowledged as critical to relating with, connecting to, and understanding others, but the underlying mechanisms of this phenomenon are poorly understood. Dance-particularly improvised dance-offers a valuable paradigm for investigating the dynamics of interpersonal coordination due to its inherent ability to connect us. However, conventional approaches to studying coordination often fail to capture the co-creative spontaneity that is intrinsic to such interactions.

Efficacy and safety of stereotactic radiosurgery with gamma knife machine in patients with essential tremor: a systematic review and single-arm meta-analysis.

Essential tremor (ET) is identified as the most prevalent movement disorder, primarily characterized by tremors in both upper extremities. The spectrum of surgical options for ET includes gamma knife radiosurgery (GKRS) and other stereotactic radiosurgery (SRS) modalities. Despite the limitations of these options, SRS is deemed an essential and indispensable approach.

Molecular profiles, sources and lineage restrictions of stem cells in an annelid regeneration model.

Regeneration of missing body parts can be observed in diverse animal phyla, but it remains unclear to which extent these capacities rely on shared or divergent principles. Research into this question requires detailed knowledge about the involved molecular and cellular principles in suitable reference models. By combining single-cell RNA sequencing and mosaic transgenesis in the marine annelid Platynereis dumerilii, we map cellular profiles and lineage restrictions during posterior regeneration.

Effects of eplontersen on symptoms of autonomic neuropathy in hereditary transthyretin-mediated amyloidosis: secondary analysis from the NEURO-TTRansform trial.

Background: The NEURO-TTRansform trial showed that after 66 weeks of treatment, eplontersen significantly reduced neuropathic impairment and improved quality of life (QoL) in patients with hereditary transthyretin-mediated amyloidosis with polyneuropathy (ATTRv-PN). In this secondary analysis from NEURO-TTRansform, autonomic impairment, and the impact of eplontersen on autonomic impairment progression was evaluated through 85 weeks in patients randomised to eplontersen ( = 144) versus external placebo ( = 60; through Week 66 from the NEURO-TTR trial).

Methods: Change from baseline in modified Neuropathy Impairment Score +7 (mNIS+7) composite score, Norfolk Quality of Life-Diabetic Neuropathy (Norfolk QoL-DN) total score, and the Neuropathy Symptoms and Change (NSC) total score was evaluated.

A Tropical Estuary Where Mercury Does Not Biomagnify and its Adjacent Waters that Render Extremely High Mercury Concentrations in Top Predators.

In general, mercury (Hg) undergoes biomagnification in aquatic systems. The absence of Hg biomagnification in a certain aquatic environment constitutes an exceptional finding and this seems to be the case for Sepetiba Bay, in Rio de Janeiro state (RJ), Brazil. There are three distinct ecological populations of Guiana dolphins in the Sepetiba Bay (SB)-Ilha Grande Bay (IGB) Complex, inhabiting: (1) the inner part of SB; (2) SB entrance; and (3) IGB.

Relationship between Quality of Life and Swallowing in Hypertensive Individuals with Obstructive Sleep Apnea.

Introduction: Obstructive sleep apnea (OSA) is closely associated with resistant hypertension (RHTN). Individuals with OSA may have sensory and muscular alterations in pharyngolaryngeal structures, potentially resulting in oropharyngeal dysphagia.

Objective: One objective of this study was to assess and compare the quality of life (QoL) and swallowing ability of resistant hypertensive patients with and without OSA.

Hypothyroidism modulates mitochondrial dynamics and mitophagy in the heart of rats under fed and fasting conditions.

Aims: Investigate the impact of hypothyroidism on mitochondrial dynamics and mitophagy in the heart under fed and fasting conditions.

Methods: Hypothyroidism was induced in male Wistar rats with methimazole (0.03 %) for 21 days.

Assessment of the adherence to perioperative nutritional care protocols in Brazilian hospitals: The PreopWeek study.

Objectives: The study (PreopWeek) aimed to assess the perioperative nutritional care for major surgical patients in Brazilian hospitals, focusing on adherence to emerging multimodal protocols like Enhanced Recovery After Surgery and Acceleration of Total Postoperative Recovery.

Methods: An observational cross-sectional study was conducted in Brazilian hospitals enrolled voluntarily from June 19 to June 23, 2023 (convenience sample). Data were collected through patient interviews and medical records review.

Reflectance confocal microscopy for margin mapping of melanoma of the lentigo maligna type: A systematic review and meta-analysis.

Melanoma of the lentigo maligna (LM) type and its invasive counterpart, lentigo maligna melanoma (LMM), occur in chronically sun-damaged skin and tend to have subclinical extension that makes presurgical margin mapping challenging. Reflectance confocal microscopy (RCM) is a non-invasive imaging modality that enables in vivo visualization of the skin at the cellular level, allowing for adequate estimation of LM/LMM margins. We aimed to perform a systematic review and meta-analysis evaluating RCM's performance compared with histopathology in margin mapping of LM/LMM.

Patient satisfaction with synchronous telehealth care after strabismus surgery.

Background: To measure patient satisfaction with synchronous telehealth care, we administered the Telemedicine Satisfaction Questionnaire (TSQ) to assess the quality of care provided, its similarity to face-to-face meetings, and patients' perception of the interaction.

Methods: The Portuguese version of the TSQ was administered during 2022 to patients who received postoperative synchronous telehealth care after strabismus surgery in Curitiba, Brazil, from 2020 to 2022. The interval between the questionnaire application and teleconsultation ranged from 2 to 22 months after the telehealth encounter.

Cystic Lesions and Odontogenic Tumors in Older People: A Brazilian Multicenter Study.

Background: Some odontogenic cysts (OCs) and odontogenic tumors (OTs) are infiltrative and often recur, causing bone destruction and tooth loss. In the elderly, in particular, these injuries cause significant morbidity, making rehabilitation difficult and compromising the quality of life of these individuals. Objective: To determine the prevalence and demographic characteristics of OCs, non-odontogenic cysts (NOCs), and OTs diagnosed in an elderly Brazilian population (≥60 years).