45 results match your criteria: "Federal University of Pernambuco. Recife[Affiliation]"

Article Synopsis
  • Schistosomiasis mansoni (SM) leads to periportal fibrosis (PPF) due to inflammation from parasite eggs, resulting in collagen and matrix protein buildup in the liver.
  • The study involved 242 individuals infected with S. mansoni in Pernambuco, Brazil, assessing the link between MMP-3 gene polymorphism (-1171 5A>6A) and PPF, alongside various sociodemographic factors.
  • Findings revealed no significant link between MMP-3 polymorphism and PPF; however, male gender and age over 41 were identified as predictors for the hepatosplenic form of the disease.
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Thermal efficiency dataset around Cuban seas (TEDACS).

Open Res Eur

January 2024

Laboratory of Physical, Coastal and Estuarine Oceanography (LOFEC)., Federal University of Pernambuco, Pernambuco, Recife-PE, Brazil.

Currently, the generation of electrical energy in Cuba is supported by oil and natural gas. These sources, as it is known, are directly linked to large emissions of pollutants that are released into the environment. Therefore, it is necessary to search for new energy options that are directed towards sustainable development, allowing the preservation of natural ecosystems.

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Surface-enhanced Raman scattering (SERS) is a sensitive and fast technique for sensing applications such as chemical trace analysis. However, a successful, high-throughput practical implementation necessitates the availability of simple-to-use and economical SERS substrates. In this work, we present a robust, reproducible, flexible and yet cost-effective SERS substrate suited for the sensitive detection of analytes at near-infrared (NIR) excitation wavelengths.

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The advent of technological developments is allowing to gather large amounts of data in several research fields. Learning analytics (LA)/educational data mining has access to big observational unstructured data captured from educational settings and relies mostly on unsupervised machine learning (ML) algorithms to make sense of such type of data. Generalized additive models for location, scale, and shape (GAMLSS) are a supervised statistical learning framework that allows modeling all the parameters of the distribution of the response variable with respect to the explanatory variables.

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The objective of this study was to observe patients' satisfaction with their in-service direct anterior dental restorations and to compare it with clinical evaluation using FDI (Federation Dental International) criteria. Patients scored their own anterior dental restorations regarding satisfaction (satisfactory /dissatisfactory). If dissatisfaction was mentioned, then, they would be interviewed about the complaint.

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The excess of minerals in the industrial substrates is detrimental for Saccharomyces cerevisiae ethanol fermentation performance. In this work, we sought to understand the effect of some of those minerals on the physiology of Dekkera bruxellensis. Three groups of minerals were classified on the basis of the aerobic growth profiles on glucose: neutrals (K+, Mg2+, P5+ and Zn2+), inducers (Mn2+ and Ca2+) and inhibitors (Al3+, Cu2+ and Fe2+).

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Virulence factors of Gram-negative bacteria from free-ranging Amazon river dolphins (Inia geoffrensis).

Antonie Van Leeuwenhoek

May 2023

Laboratory of Emerging and Reemerging Pathogens, Postgraduate Program in Medical Microbiology, Federal University of Ceará, Rua Coronel Nunes de Melo, 1315. Fortaleza, CEP: 60.430-275, FortalezaCeará, Brazil.

Freshwater cetaceans play a significant role as sentinel animals, providing important data on animal species and aquatic ecosystem health. They also may serve as potential reservoirs of emerging pathogens and host virulence genes in their microbiota. In this study, we evaluated virulence factors produced by Gram-negative bacteria recovered from individuals belonging to two populations of free-ranging Amazon river dolphins (Inia geoffrensis).

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Background: Enuresis is an involuntary and intermittent loss of urine during sleep, and its treatment can be done by pharmacological and non-pharmacological strategies.

Objective: To conduct an overview to carry out a survey of the systematic reviews about treatment options for children/adolescents with enuresis.

Methods: Databases used were Cochrane Library, PROSPERO, MEDLINE/PubMed, EMBASE, LILACS/BVS, PEDro, SciELO and Google Scholar.

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High-resolution hydrodynamics and TS structure database of the Brazilian continental shelf and adjacent waters.

Data Brief

June 2022

Laboratoire d'Etudes en Géophysique et Océanographie Spatiales (LEGOS), 18 avenue Edouard Belin, 31401 Toulouse Cedex 9, France.

This data set was obtained from two ROMS model simulations in the region of Brazil located at 60°W-15°W / 25°S - 15°N. One of the simulations takes into account the tide (obtained from the TPXO7 product) and the other one does not. The rest of the configuration was similar for both simulations, taking bathymetry from ETOPO2 and surface forcings from COADS climatology.

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Protein detection by fluorescence of manually cleaned high-speed dental handpieces.

Infect Control Hosp Epidemiol

May 2023

Medical Surgical Nursing Department, Escola de Enfermagem, Universidade de São Paulo, São Paulo, Brazil.

We analyzed the effectiveness of manual cleaning protocols performed on high-speed dental handpieces, using protein identification by fluorescence. Although one protocol was able to able to lower the amount of protein, >40% of the handpieces showed amounts of residual protein at unacceptable levels.

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Objective: To evaluate, using semiparametric methodologies of survival analysis, the relationship between covariates and time to death of patients with breast cancer, as well as the determination discriminatory power in the conditional inference tree of patients who had cancer.

Methods: A retrospective cohort study was conducted using data collected from medical records of women who had breast cancer and underwent treatment between 2005 and 2015 at the Hospital da Fundação de Assistencial da Paraíba in Campina Grande, State of Paraiba, Brazil. Survival curves were estimated using the Kaplan-Meier method, Cox regression, and conditional decision tree.

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The Tropical Atlantic Ocean Database and Monthly Anomalies of River Discharge on Atlantic Ocean datasets encompass the monthly anomalies of a variety of physical, biogeochemical parameters from the tropical Atlantic Ocean and the monthly anomalies of river runoff in the Atlantic Ocean and its adjacent seas. The parameters used as the base for the computation of anomalies come from the TROPFLUX, GPCP, ASCAT, SODA, GODAS, DASK, SeaWiFS, OAFLUX, WAVEWATCH III, NOAA/ESRL 20th Century Reanalysis, GLOBAL_REANALYSIS_BIO_001_029, GLOBAL_REANALYSIS_BIO_001_033, OCEANCOLOUR_GLO_OPTICS_L4_REP_OBSERVATIONS_009_081, OSCAR, SMOS, MODIS-Aqua, CO2_Flux, and GRDC datasets. Several of the anomaly data are redundant, but come from different data sources making comparative studies possible.

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Sarcopenia refers to the age-related loss of muscle strength and muscle mass, which is associated with a reduced quality of life, particularly in older females. Resistance training (RT) is well established to be an effective intervention to counter indices of sarcopenia. Accumulating research indicates that the addition of creatine supplementation (Cr) to RT augments gains in muscle strength and muscle mass, compared to RT alone.

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The identification of specific biomarkers for Zika infection and its clinical complications is fundamental to mitigate the infection spread, which has been associated with a broad range of neurological sequelae. We present the characterization of antibody responses in serum samples from individuals infected with Zika, presenting non-severe (classical) and severe (neurological disease) phenotypes, with high-density peptide arrays comprising the Zika NS1 and NS2B proteins. The data pinpoints one strongly IgG-targeted NS2B epitope in non-severe infections, which is absent in Zika patients, where infection progressed to the severe phenotype.

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This study aimed to investigate the effects of acute capsaicin analog (Capsiate - CAP) supplementation on maximal voluntary isometric contraction (MVIC) performance in healthy young men. Thirteen subjects (25.2±3.

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Background Maternal chronic hypertension is associated with adverse pregnancy outcomes. Previous studies examined the association between either chronic hypertension or antihypertensive treatment and adverse pregnancy outcomes. We aimed to synthesize the evidence on the effect of chronic hypertension/antihypertensive treatment on adverse pregnancy outcomes.

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Background This study compared left ventricular (LV) characteristics between patients with type-A and type-B aortic dissection (AD) and evaluated the ability of LV remodeling phenotypes (hypertrophy, concentricity, or geometric patterns) to predict mortality in both AD types. Methods and Results We evaluated 236 patients with type A and 120 patients with type B who had echocardiograms within 60 days before or after AD diagnosis (median [25th, 75th percentiles] time difference between echocardiogram and AD diagnosis=1 [0, 6] days) from 3 centers. Patients were stratified according to LV phenotypes, and early (90-day) and late (1-year) mortality after AD diagnosis were assessed.

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Levodopa-induced dyskinesia (LID) is an adverse effect that negatively impacts the quality of life of patients with Parkinson's disease (PD). Studies report that genetic variations in the genes of the pharmacogenetic pathway of the levodopa (L-DOPA) might be associated with LID development. The goal of the present study was to investigate a possible influence of functional genetic variants in the DRD1 (rs4532), DRD2 (rs1800497), DAT1 (rs28363170), and COMT (rs4680) genes with LID development.

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A way to promote patient safety is to create strategies that can contain the latent failures present in health organizations, especially in highly complexity services, such as hemodialysis units, which, by the characteristics of the treatment, offer potential risks for the occurrence of adverse events to their patients. The aim of this study was to identify strategies in the literature that contribute to the promotion of patient safety in hemodialysis. Eleven articles were identified, comprising 17 strategies to promote patient safety in hemodialysis, divided into three dimensions of care: teaching, assistance, and management.

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cGMP signaling pathway in hepatic encephalopathy neuroinflammation and cognition.

Int Immunopharmacol

February 2020

Laboratory of Ultrastructure, Aggeu Magalhães Institute (IAM), Recife, Pernambuco, Brazil; Institute of Science and Technology on Neuroimmunomodulation (INCT-NIM), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil. Electronic address:

Hepatic encephalopathy (HE) is a complex neuropsychiatric syndrome that results from liver failure and is characterized by a wide range of symptoms such as alteration in the sleep-waking cycle, neuromuscular coordination, mood, and cognition. The deregulation of nitric oxide (NO)/cyclic guanosine monophosphate (cGMP)/protein kinase G (PKG) signaling pathway is thought to play an important role in the etiology and progression of neurodegenerative diseases, and several studies pointed that the cGMP signaling is impaired in patients with HE and experimental models of chronic hyperammonemia. This review aimed to briefly present the current knowledge of the cGMP signaling pathways in neuroinflammation, neurogenesis, and memory in hepatic encephalopathy and its potential therapeutic role.

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Children with cerebral palsy (CP) often exhibit difficulties in feeding resulting from deficits in chewing. This study investigates the therapeutic potential of L-tryptophan (TRI) to reduce deficits in chewing in rats subjected to an experimental model of CP. A total of 80 Wistar albino rats were used.

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Tadalafil restores long-term memory and synaptic plasticity in mice with hepatic encephalopathy.

Toxicol Appl Pharmacol

September 2019

Laboratory of Ultrastructure, Aggeu Magalhães Institute (IAM), Recife, Pernambuco, Brazil; Institute of Science and Technology on Neuroimmunomodulation (INCT-NIM), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil. Electronic address:

Background And Aim: Tadalafil displays important neuroprotective effects in experimental models of neurodegenerative diseases, however its mechanisms of action remain poorly understood. The aim of the present study was to investigate the action of Tadalafil on learning and memory, neuroinflammation, glial cell activation and neuroprotection in the experimental model of hepatic encephalopathy (HE) induced by Thioacetamide (TAA) in mice.

Methods: Mice received intraperitoneal injections of TAA, for 3 consecutive days, reaching the final dose of 600 mg/kg.

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The study objective is to describe patients and professionals' perspectives on the Tuberculosis Control Program (PCT) in Recife, Brazil, contributing to the program evaluation. A cross-sectional study was conducted in three purposively selected sites, representing the three levels of care in the public health system. All eligible PCT patients in sites A, B and C were invited to participate (n = 123).

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Visual hallucinations are significant nonmotor symptoms in the course of treatment of Parkinson's disease. Previous studies have shown that the interindividual variability and pharmacogenetic profile of Parkinson's disease patients seem to influence the occurrence of visual hallucinations. In our study, we investigated a possible relationship of sequence variants in DRD1, DRD2, DRD3, DAT1, and COMT genes with the presence of visual hallucinations in Parkinson's disease patients.

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