The Efficacy and Safety of Antifungal Agents for Managing Oral Candidiasis in Oncologic Patients: A Systematic Review With Network Meta-Analysis.

This study aimed at synthesizing the available evidence on the comparative safety and efficacy of antifungal agents for preventing or treating oral candidiasis (OC) in oncologic patients. A systematic review following international recommendations was performed (PROSPERO CRD42024507745). A comprehensive search was conducted in PubMed, Scopus, and Web of Science (Feb 2024) to retrieve randomized controlled trials evaluating the clinical effects of antifungal agents in the management of OC in this vulnerable population.

Synthesis of a Bioactive Nitric Oxide-Releasing Polymer from S-Nitrosated Starch.

The incorporation of nitric oxide (NO) into polymeric matrices minimizes degradation and facilitates controlled release. This optimization increases the field of application of NO, in dressings, food protective films, and implant devices, among others. This work presents an economical and easy way to manufacture bioactive nitric oxide-releasing polymer (BioNOR-P) and evaluates its bactericidal and antioxidant activity (AA), mechanical behavior, cytotoxicity, and genotoxicity, seeking future use in different applications.

Quality and stability of meat products prepared with chicken fillets affected by white striping myopathy.

This study aimed to evaluate the quality and oxidative stability of chicken burger and mortadella prepared with fillets affected by white striping (WS) myopathy as compared with products prepared with normal fillets (control) There were no differences in pH, L*, or b* between treatments (WS vs. control); however, water holding capacity was higher in control burgers and mortadellas. In burgers, the use of WS fillet led to an increase in lipid content and a reduction in moisture content.

Trace elements and high sulfur levels in the blood of rehabilitated eastern Mediterranean Sea green sea turtles (Chelonia mydas).

The Eastern Mediterranean Sea (EMS) exhibits high temperature and salinity, low levels of biologic production and is considered oligotrophic. Nonetheless, it is also a hotspot of biodiversity, with several important endangered flagship species, including several species of sea turtles. These turtles serve as bioindicators for the health of their ecologic systems, due to changes in diet, habitat and migration patterns that characterize different stages in their lives.

Tailored Nanoarchitectures: MoS₂/Graphene and MoS/Graphene Oxide Thin Films via Liquid-Liquid Interfacial Route.

The nanostructured assembly of different two-dimensional (2D) materials in specific organization is crucial for developing materials with synergistic properties. In this study, we present a general methodology to prepare thin, transparent and self-assembled films of 2D/2D composites based on molybdenum sulfide (MoS)/graphene oxide (GO) or MoS/reduced graphene oxide (rGO), through the liquid/liquid interfacial route. Different nanoarchitectures are obtained by changing simple experimental parameters during the thin film preparation steps.

Cold-driven strategies as pre-fermentative techniques on winemaking: A review.

As a pre-fermentative practice, cold may facilitate the extraction of grape compounds, resulting in differentiated wines. To explore the potential of these practices, extensive research has been conducted on scientific publications since 2004. There are four main ways to apply cold in pre-fermentative practices: ice wine production, berry freezing, cold maceration of grape must, and cryoconcentration of grape must.

Highest oxygen consumption prediction: introducing variable theoretical proportional factors for different sports.

Purpose: The use of a fixed theoretical-proportional-factor (TPF) is one of the indirect highest-oxygen-consumptions (HOC) assessment methods, but it may not accurately reflect the physiological differences across various sports (cycling-triathlon-running-football-multisport). The aim of this study is to evaluate the variability of TPF across different sports, proposing a series of sport-specific new TPF values for more accurate HOC estimation.

Methods: A sample of 340 adults (26.

Reproduction has immediate effects on female mortality, but no discernible lasting physiological impacts: A test of the disposable soma theory.

The disposable soma theory (DST) posits that organisms age and die because of a direct trade-off in resource allocation between reproduction and somatic maintenance. DST predicts that investments in reproduction accentuate somatic damage which increase senescence and shortens lifespan. Here, we directly tested DST predictions in breeding and nonbreeding female C57BL/6J mice.

Auranofin is active against Histoplasma capsulatum and reduces the expression of virulence-related genes.

Background: Auranofin is an approved anti-rheumatic drug that has a broad-range inhibitory action against several microorganisms, including human pathogenic fungi. The auranofin activity against Histoplasma capsulatum, the dimorphic fungus that causes histoplasmosis, has not been properly addressed. Since there are few therapeutic options for this life-threatening systemic mycosis, this study evaluated the effects of auranofin on H.

Hydrochar from sawdust and sewage sludge - a potential media for retaining heavy metals in sustainable drainage systems (SuDS).

Waste valorization is an essential aspect of sustainable development. From this perspective, co-hydrothermal carbonization (Co-HTC) is a promising thermochemical process for converting organic waste into hydrochar. Hydrochar is a solid material whose physicochemical properties could make it suitable for adsorbing pollutants such as heavy metals.

49,XXXXY PATIENT AND INCIDENTAL FINDING OF LOW LEVEL MOSAIC 45,X IN THE MOTHER.

Context: 49,XXXXY syndrome is an aneuploidy that affects males and is commonly referred to as a variant of Klinefelter Syndrome. It presents a frequency of 1:85,000 to 100,000 births and an etiology related to non-disjunction of homologous chromosomes. Findings include skeletal abnormalities, hypogonadism, and cognitive impairment.

Investigating Molecular Adsorption on Graphene-Supported Platinum Subnanoclusters: Insights from DFT + D3 Calculations.

Platinum (Pt) subnanoclusters have become pivotal in nanocatalysis, yet their molecular adsorption mechanisms, particularly on supported versus unsupported systems, remain poorly understood. Our study employs detailed density functional theory (DFT) calculations with D3 corrections to investigate molecular adsorption on Pt subnanoclusters, focusing on CO, NO, N, and O species. Gas-phase and graphene-supported scenarios are systematically characterized to elucidate adsorption mechanisms and catalytic potential.