8,963 results match your criteria: "Federal University of Minas Gerais.[Affiliation]"

Article Synopsis
  • Post COVID-19 condition (PCC) refers to ongoing symptoms that persist for at least one month after recovering from acute COVID-19, and the study analyzed risks associated with different viral variants among 7,699 hospitalized patients.
  • The research found that the most common PCC symptoms were fatigue, brain fog, and respiratory issues, with the original wild-type virus being the most prevalent among participants, followed by Alpha, Delta, Gamma, and Omicron variants.
  • Results indicated that infection with Omicron was linked to a lower risk of developing PCC compared to the wild-type strain, while Alpha and Delta variants were associated with a higher risk; ICU admission was a significant factor influencing severity and PCC risk.
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  • * Researchers analyzed the blood of 27 CHIKV-positive patients and 9 healthy controls, finding significant increases in transcription factors and cytokines linked to various T cell types, especially RORγt.
  • * The study revealed complex immune interactions during CHIKV infection, noting that higher levels of some immune markers are associated with either lower or higher viral loads, enhancing understanding of disease mechanisms.
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  • The study investigates how temperature affects the viral cycles of Zika (ZIKV) and Chikungunya (CHIKV) in mammalian (Vero) and mosquito (C6/36) cells.
  • At two temperatures, 28 °C and 37 °C, researchers compare the virus's genome quantification to its infectivity in both cell types.
  • Techniques like transmission electron microscopy reveal unique interactions, such as CHIKV's "virus-surfing" behaviors and its larger forms, while ZIKV is less prevalent in mosquito cells compared to mammalian cells.
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  • * Genomic analyses revealed that MRSP strains have larger genomes with more antimicrobial resistance genes and virulent markers than MSSP strains, indicating heightened pathogenicity in MRSP infections.
  • * Pangenome analysis identified a large number of both core and variable genes, while phylogenomic analysis effectively differentiated MRSP from MSSP strains, suggesting distinct evolutionary pathways that are essential for developing strategies to combat resistant infections.
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  • The study examined the oral health issues in individuals with rare genetic conditions affecting skeletal development compared to those without such diseases.
  • It involved 210 participants aged 2 to 54, with half having conditions like mucopolysaccharidosis (MPS) and osteogenesis imperfecta (OI), and the other half being healthy individuals recruited from similar locations in Brazil.
  • Results indicated that those with rare diseases were significantly more likely to experience dental problems, being 12.9 times more likely to have oral issues than their counterparts without rare conditions.
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Diet and Oral Squamous Cell Carcinoma: A Scoping Review.

Int J Environ Res Public Health

September 2024

Faculty of Medical Sciences of Minas Gerais, Alameda Ezequiel Dias, 275, Belo Horizonte 30130-110, MG, Brazil.

Article Synopsis
  • Oral squamous cell carcinoma (OSCC) is a prevalent cancer worldwide, with rising cases among non-smokers prompting a need to investigate dietary influences alongside smoking.
  • This scoping review utilized a systematic approach to assess the relationship between diet and OSCC, analyzing data from 17 studies involving over 10,000 patients primarily from countries with high human development.
  • Findings suggest that higher consumption of fruits, vegetables, and tea may reduce OSCC risk, while diets high in salty meats, dairy, and fried/spicy foods could increase it, highlighting the need for standardized research to clarify these associations.
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Background: Screen time, involving activities like watching television (TV), and using tablets, mobile phones, and computers (electronic devices), is associated with the consumption of unhealthy foods. This study aimed to analyze the association between prolonged leisure screen time and healthy and unhealthy food consumption indicators among Brazilian adults (≥18 years).

Methods: Data from the National Health Survey (NHS), conducted in 2019 (n = 88,531), were used.

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  • Scientists used a technique called Transcranial Magnetic Stimulation (TMS) to study how our brains control movement and the sounds we hear.
  • They found that TMS can help improve how people tell different sounds apart, showing that it can change how our brains work.
  • Their results suggest that TMS might be a good way to understand brain activity better, especially in how we process different types of sounds.
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Background: is a leading causative agent of dental caries and exerts pathogenicity by forming biofilms. Dental caries continues to be a significant public health issue worldwide, affecting an estimated 2.5 billion people, showing a 14.

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Droplet Digital PCR for Diagnosis in Bronchoalveolar Lavage Samples from Patients with Ventilator-Associated Pneumonia.

Antibiotics (Basel)

September 2024

Departament of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Av. Pres. Antônio Carlos 6627, Pampulha, Belo Horizonte 31270-901, Minas Gerais, Brazil.

Article Synopsis
  • Advanced diagnostic technologies like droplet digital PCR (ddPCR) provide a precise way to identify and measure pathogens in mini bronchoalveolar lavage samples for diagnosing ventilator-associated pneumonia (VAP).
  • VAP is a serious lung infection in patients on ventilators, making accurate and timely diagnosis essential for effective treatment and reducing patient risk.
  • The study found that ddPCR was more sensitive and able to detect pathogens in a higher percentage of clinical samples compared to traditional methods, while also avoiding issues with calibration curves.
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Feasibility of new polymeric matrices in the production of ferrous sulphate dosimeters.

Appl Radiat Isot

December 2024

Federal University of Minas Gerais (UFMG), Department of Nuclear Engineering, Campus of UFMG, Pampulha, 31.270-901. Belo Horizonte, Brazil; Nuclear Technology Development Center (CDTN) / Brazilian National Nuclear Energy Commission, Campus of UFMG, Pampulha, 31.270-901, Belo Horizonte, Brazil. Electronic address:

External beam radiotherapy is a treatment modality that employs high doses for curative or palliative purposes. Safety in such treatments, particularly with high-precision equipment, necessitates strict adherence to quality control protocols to ensure the efficacy of oncological treatments. In this context, chemical dosimeters, particularly the Fricke gel, have emerged as valuable tools for quantitatively analysing absorbed radiation doses.

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Article Synopsis
  • Tupanviruses are a type of virus that infect special cells in the immune system called phagocytes.
  • Scientists discovered how certain metal ions and hydrogen peroxide can cause these viruses to open up in a specific way.
  • This opening might release the part of the virus that is needed to start an infection, making the treated viruses no longer able to infect cells.
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Background:  Mucosal visualization during upper gastrointestinal (UGI) endoscopy can be impaired by the presence of foam, bubbles, and mucus. Some UGI endoscopy visibility scales have been proposed but have not undergone multicenter validation. This study aimed to develop and validate the Gastroscopy RAte of Cleanliness Evaluation (GRACE) scale.

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Oral health-related quality of life (OHRQoL) is a multifaceted concept that surpasses an exclusively clinical perception and includes functional, social, emotional, and environmental issues. The measure of OHRQoL represents a holistic approach for research and clinical practice. Negative impacts of oral conditions on OHRQoL in childhood can reflect on health development, especially in a life stage marked by social and cognitive maturation.

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Tooth hypersensitivity is a common symptom in molar incisor hypomineralisation (MIH) patients and can affect children's quality of life. During daily routine, children with MIH often report sensitivity to various thermal and mechanical stimuli, and difficulty in achieving effective analgesia is a common issue becoming a challenge for dentists. Research has focused on the possible pathophysiological mechanisms behind this phenomenon, which, in turn, have not been determined.

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Investigate individual and contextual determinants associated with bullying in schoolchildren eight to ten years of age. A cross-sectional study was conducted with 739 schoolchildren, who answered a question about episodes of bullying related to oral health and questionnaires addressing childhood anxiety and orofacial dysfunction. The guardians provided information on sociodemographic characteristics, sleep disorders, and oral health literacy.

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Systemic Mycoses by Novel Onygenalean Fungal Pathogens spp and in Rwanda.

Open Forum Infect Dis

September 2024

Microbiology and Molecular Genetics, Biomedical Laboratory Diagnostics, Michigan State University, East Lansing, Michigan, USA.

Article Synopsis
  • Two unique cases of fungal infections were reported in Rwanda, which are not commonly seen in the region.
  • One patient had emergomycosis with widespread disease affecting the skin, while the other had African blastomycosis involving both skin and bones.
  • These cases provide insights into the clinical, pathological, and genetic characteristics of new fungal species in Rwanda.
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P-glycoprotein expression is decreased in placenta accreta and placenta previa disorders.

Minerva Obstet Gynecol

December 2024

Department of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Florence, Italy.

Background: P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are multidrug resistance (MDR) transporters that function as placental gatekeepers, lowering the fetal levels of diverse xenobiotics and toxins that may be circulating in the maternal blood throughout pregnancy. Placenta accreta spectrum (PAS) and the placenta previa (PP) disorders are obstetric pathologies encompassed by an abnormal invasion of chorionic villous tissue in the uterine wall or at the endocervical os, respectively. Given the fact that MDR transporters are involved in placentation and are highly responsive to inflammation, we hypothesized that immunostaining of P-gp and BCRP would be altered in PAS and in PP specimens.

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Kidney transplantation reduces biomarkers of endothelial dysfunction.

J Nephrol

September 2024

Interdisciplinary Laboratory of Medical Investigation, Unit of Pediatric Nephrology, Department of Pediatrics, Faculty of Medicine, Federal University of Minas Gerais (UFMG), Avenida Alfredo Balena, 190, 2Nd Floor, Room #281, Belo Horizonte, MG, Brazil.

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Purpose: Evidence from animal and human studies demonstrates that cortical regions play a key role in autonomic modulation with a differential role for some brain regions located in the left and right brain hemispheres. Known as autonomic asymmetry, this phenomenon has been demonstrated by clinical observations, by experimental models, and currently by combined neuroimaging and direct recordings of sympathetic nerve activity. Previous studies report peculiar autonomic-mediated cardiovascular alterations following unilateral damage to the left or right insula, a multifunctional key cortical region involved in emotional processing linked to autonomic cardiovascular control and featuring asymmetric characteristics.

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Purpose: To compile and synthesise the evidence regarding the effectiveness of aerobic exercise (AE) compared with other treatments to reduce pain and disability of individuals with orofacial pain (OFP).

Methods: Electronic searches were conducted on five databases (MEDLINE, Embase, CINAHL, Cochrane Library, and Scopus). Randomised controlled trials (RCT) or controlled trials including adults of both sexes with painful OFP diagnoses were targeted.

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Background: Surgical site infection (SSI) remains a challenge in healthcare, contributing to prolonged hospital stays, increased healthcare costs, and adverse patient outcomes, including mortality. Effective preoperative skin disinfection interventions, such as povidone-iodine (PVI) and chlorhexidine (CHG), are widely used but their efficacy remains debated. To address this gap, this meta-analysis aims to evaluate the efficacy of PVI and CHG.

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A single session of strength training changed plasma levels of resistin, but not leptin in overweight and obese men.

Sports Med Health Sci

December 2024

Laboratory of Inflammation and Exercise Immunology, Department of Physical Education, School of Physical Education, Federal University of Ouro Preto, Ouro Preto, MG, Brazil.

Article Synopsis
  • Obesity is a complex condition linked to excessive fat accumulation, especially in the abdominal area, which can harm health by increasing inflammation.
  • This study focused on 12 sedentary, overweight, and obese young men and assessed the effects of one strength training session on their blood levels of resistin and leptin, two important adipokines.
  • Results showed that the strength training significantly decreased resistin levels one hour post-exercise, while leptin levels remained unchanged, suggesting that exercise may help reduce inflammation and improve insulin resistance in overweight and obese individuals.
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Severe mental illnesses (SMI), especially schizophrenia and bipolar disorder (BD), are associated with significant distress to patients, reduced life expectancy and a higher cost of care. There is growing evidence that SMI may increase the risk of dementia in later life, posing an additional challenge in the management of these patients. SMI present a complex and highly heterogeneous pathophysiology, which has hampered the understanding of its underlying pathological mechanisms and limited the success of the available therapies.

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The soil conservation agenda of Brazil: A review of "edge-to-edge" science contributions.

Sci Total Environ

December 2024

CQVR - Vila Real Chemistry Center, University of Trás-os-Montes and Alto Douro, Ap. 1013, 5001-801 Vila Real, Portugal; POLUS-Land Use Policy Group, Paulista State University (UNESP), Access Way Prof. Paulo Donato Castellane, s/n, Jaboticabal, SP 14884-900, Brazil. Electronic address:

Soil conservation adheres to various United Nations Sustainable Development Goals while in Brazil is a constitutional obligation. To attain the goals and fulfil the obligation, laws, policies, governance and science must be imbricated to deliver suitable conservation solutions for the long term, namely appropriate to positively influence other downstream chains such as the food chain. However, in Brazil, a major world producer and exporter of food, weaknesses were recently diagnosed by judicial authorities concerning soil governance and coordinated land use policies.

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