8,962 results match your criteria: "Federal University of Minas Gerais.[Affiliation]"

Article Synopsis
  • - The study aims to determine if adding lifestyle education to a physical exercise program improves various health outcomes for individuals with prediabetes or diabetes compared to exercise alone, focusing on areas like functional capacity, disease knowledge, and quality of life.
  • - It is a multicenter, double-blinded, randomized controlled trial lasting 12 weeks, followed by a 6-month assessment, involving adults who meet specific health criteria and are recruited from two Brazilian cities.
  • - Outcomes being measured include improvements in health behaviors, cardiometabolic health parameters, depression, and diet quality, alongside the primary outcomes of functional capacity and disease-related knowledge.
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  • The study aimed to analyze the temperature differences in the lips and facial points of mouth-breathing versus nasal-breathing children aged 4 to 11.
  • It involved a sample of 60 children, with infrared thermograms taken to assess various thermoanatomic points and lip areas.
  • Findings indicated that mouth-breathers had lower temperatures in areas closer to the lips compared to nasal-breathers, suggesting that thermography could be a valuable diagnostic tool for identifying breathing patterns in children.
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Nitrites have emerged as promising therapeutic agents for cardiovascular diseases, alongside nitrates. While chronic use of organic nitrates is well recognized to lead to vascular tolerance, the tolerance associated with nitrite therapy remains incompletely understood. The aim of the present study was to investigate vascular tolerance to sodium nitrite and the underlying molecular mechanisms.

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Background: Non-village indigenous people may face urban lifestyle influences, impacting their nutritional profile. Therefore, this study aimed to analyze the temporal trends in the nutritional status (2008-2023) and food consumption (2015-2023) of non-village indigenous people in Brazil, using data from the Food and Nutrition Surveillance System (SISVAN).

Methods: In this time series study, secondary data available on the SISVAN online platform were used.

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Purpose: Family caregivers of care-dependent patients experience a decline in their Quality of Life (QoL). However, the determinants contributing to this decrease in QoL are still not fully understood. Therefore, this study aimed to estimate prospectively the determinants contributing to decreased QoL among family caregivers of care-dependent patients.

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  • A systematic review compared the effectiveness and safety of oral versus topical minoxidil in treating androgenetic alopecia, analyzing data from four randomized clinical trials involving 279 patients.
  • The study found no significant differences between the two forms of minoxidil regarding hair density and diameter, suggesting both treatments are similarly effective.
  • However, oral minoxidil resulted in a higher occurrence of hypertrichosis (excess hair growth), while the incidence of hypotension was not significantly different between the two groups.
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Background: Despite the increasing burden of cardiovascular diseases (CVDs), there is a shortage of vascular surgeons worldwide, with a higher scarcity in low- and middle-income countries. The objective of the present study was to report the current status of vascular surgery education and training on the American continent.

Methods: Official government, postgraduate medical schools, and medical associations' websites were searched for data regarding vascular surgery training positions, programs, and pathways available in the 35 countries of the American continent.

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The aim was to investigate the effects of different volumes of strength training (ST) in association with photobiomodulation (PBMt) in mice fed a high-fat diet (HFD) on insulin resistance (IR). Male Swiss albino mice were fed HFD and performed high- or low-volume (one-third) ST (3 days/week), associated with PBMt (660 nm + 850 nm; ~42 J delivered) or not (lights off). ST improved IR, lowered visceral adiposity and circulating cytokines, and increased skeletal muscle hypertrophy and mitochondrial activity.

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Background: The COVID-19 pandemic has spread through pre-existing fault lines in societies, deepening structural barriers faced by precarious workers, low-income populations, and racialized communities in lower income sub-city units. Many studies have quantified the magnitude of inequalities in COVID-19 distribution within cities, but few have taken an international comparative approach to draw inferences on the ways urban epidemics are shaped by social determinants of health.

Methods: Guided by critical epidemiology, this study quantifies sub-city unit-level COVID-19 inequalities across eight of the largest metropolitan areas of Latin America and Canada.

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Adipose tissue dysfunction influences the development of dyslipidemias associated with obesity, however, the mechanisms are still unclear. In this sense, the literature highlights the role of copper in cholesterol synthesis, contributing to the increase in concentrations of this lipid fraction and consequently to the manifestation of dyslipidemia. The objective of the study was to investigate the relationship between copper parameters and lipid profile markers in women with obesity.

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Despite numerous studies on Salmonella enterica subsp. enterica serovar Typhimurium, the underlying mechanisms of several aspects of its virulence are still under investigation, including the role of the pdu and ttrA genes, associated with the metabolism of 1,2-propanediol using tetrathionate as an electron acceptor respectively. Our objective was to contribute to an understanding of the role of these genes inbacterial virulence for mice (Mus musculus) using an S.

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A Complex Relationship Among the Circadian Rhythm, Reward Circuit and Substance Use Disorder (SUD).

Psychol Res Behav Manag

October 2024

Division of Addiction Research & Education, Center for Sports, Exercise, and Mental Health, Western University Health Sciences, Pomona, CA, 91766, USA.

The human brain not only controls the various physiological functions but is also the prime regulator of circadian rhythms, rewards, and behaviors. Environmental factors, professional stress, and social disintegration are regarded as the initial causative factors of addiction behavior. Shift work, artificial light exposure at night, and chronic and acute jet lag influence circadian rhythm dysfunction.

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A Mixture of Four Probiotic Strains (Probiatop®) Mitigates Food Allergy to Ovalbumin in Mice.

Probiotics Antimicrob Proteins

October 2024

Department of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Av. Antônio Carlos, Belo Horizonte, MG, 6627, 30270-901, Brazil.

Article Synopsis
  • Food allergy results from a breakdown in the body's ability to tolerate certain foods, leading to various symptoms ranging from mild discomfort to severe reactions like anaphylaxis.
  • Current treatment mainly involves eliminating trigger foods, which can harm nutrition and impact social life, highlighting the need for alternative therapies.
  • The study examines the probiotic blend Probiatop®, showing that it can reduce allergy symptoms, improve gut health, and positively affect gut bacteria in models of food allergy to ovalbumin.
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Introduction: The erector spinae plane block (ESPB) has recently emerged as a regional anesthesia technique for perioperative pain management in pediatric cardiac surgery. However, evidence comparing its effectiveness with intravenous (IV) opioid-based analgesia is limited. We aimed to evaluate and compare the analgesic efficacy of ESPB versus IV opioids in this setting.

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Background: Gaucher's disease (GD), a lysosomal storage disorder, poses significant treatment challenges. This 23-year study assesses survival rates and treatment efficacy in Brazilian GD patients, integrating data from a 16-year cohort (2000-2015) and the TABNET/DATASUS medicines distribution data (1999-2022).

Objective: To investigate the survival of GD patients in Brazil, identifying key risk factors and evaluating the impact of treatments funded by the Brazilian National Health System (SUS).

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Physiological adaptations of red blood cells during aestivation in the south American lungfish Lepidosiren paradoxa.

Comp Biochem Physiol A Mol Integr Physiol

January 2025

Department of Physiology and Biophysics, Institute of Biological Science, Federal University of Minas Gerais (ICB/UFMG), Belo Horizonte, Brazil. Electronic address:

The South American lungfish Lepidosiren paradoxa inhabits areas with variable pluvial regimes. During aestivation (dormancy state observed in some species during dry seasons), the prolonged period of dryness imposes osmotic stress. We aimed to investigate the physiological and morphological adaptations of RBCs in Lepidosiren paradoxa during aestivation.

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Article Synopsis
  • The study investigates the association between genetic polymorphisms (FokI and BglI) and the timing of permanent teeth eruption in children without systemic issues or trauma.
  • A total of 353 children were clinically examined, and genetic analysis was conducted using saliva samples and advanced genotyping techniques.
  • The results show that the FokI variant is linked to a significant delay in the eruption of maxillary and total permanent teeth, while BglI did not show any effect.
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  • Spine disorders are a major global disability issue, highlighting the need for improved access to high-quality spine care to foster social inclusion and dignity for affected individuals.
  • SPINE20 outlines six recommendations for G20 countries, including providing evidence-based education for health workers, affordable spine care interventions, and investing in health policy research to support rehabilitation integration.
  • Emphasizing the importance of social equity, SPINE20 urges collaborations among healthcare providers and policymakers to ensure comprehensive access to spine care, ultimately aiming to enhance population well-being and productivity.
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With the advent of the new diagnostic model for personality disorders in the 11th revision of the International Classification of Diseases (ICD-11), researchers and practitioners in World Health Organization signatory countries are urged to implement it. This study aims to develop a brief, reliable, and valid scale for assessing maladaptive personality traits according to the ICD-11 model, using the item pool of the Dimensional Clinical Personality Inventory (IDCP-2). Quantitative and qualitative criteria for item selection were applied to a sample of 251 Brazilian adults.

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  • The study focuses on the potential of yeasts from Brazilian native stingless bees to improve bioprocesses for producing biofuels, particularly ethanol and 2-phenylethanol.
  • Two yeast strains were isolated from the bees and excelled in fermenting sucrose with high efficiency, achieving over 90% and yields of 0.504 g/g, which is significant for the ethanol industry.
  • Experimental analyses indicated that these yeasts thrive under high sucrose concentrations and low pH, making them suitable for both ethanol and 2-phenylethanol production from inexpensive raw materials.
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Some studies have demonstrated the involvement of high concentrations of copper in the manifestation of insulin resistance in individuals with obesity. The objective of this study was to evaluate the copper nutritional status and its relationship with parameters of glycemic control in women with obesity. An observational case-control clinical study involving 203 women aged between 20 and 50 years, divided into two groups: obese (n = 84) and eutrophic (n = 119).

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  • - Disposing of non-biodegradable waste like polyvinylidene fluoride (PVDF) creates global environmental and economic challenges, prompting the need for innovative recycling solutions.
  • - This study focuses on using discarded PVDF ultrafiltration membranes to produce char through optimized pyrolysis, achieving a yield of 31.3% with a specific iodine number that indicates high carbon quality.
  • - Various analyses confirmed the breakdown of fluorinated bonds and identified beneficial crystalline structures in the PVDF, suggesting that the resulting char has significant potential for industrial and environmental applications within a circular economy framework.
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  • There’s a debate about how long patients with heart problems should take two types of medicine together, called dual antiplatelet therapy (DAPT).
  • Researchers wanted to see how effective and safe different lengths of DAPT are for patients who have serious heart issues and receive a special procedure to help their hearts.
  • They found that taking DAPT for just 1 month followed by another medicine might reduce serious bleeding, but didn't change the number of heart problems compared to taking DAPT for 12 months.
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  • The pilot study examined financial losses and risk factors associated with hamstring injuries in elite Brazilian soccer players, with a focus on 34 male athletes over a 12-month season.
  • Nine hamstring injuries were confirmed in eight players, leading to an average recovery time of 22 days and a potential financial loss of $43.2 million USD for the team.
  • Factors linked to a higher risk of injury included past injuries, reduced knee flexor strength, decreased ankle flexibility, and a higher hamstring fatigue index, suggesting the need for preventive measures for those at higher risk.
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  • Accidental ureteric injury during colorectal surgery can lead to serious complications like urinary tract infections and kidney damage, but using double J stents may help avoid these injuries.
  • A review of 11 studies with over 71,000 patients showed no significant reduction in ureteral injuries with stent use, though it was linked to longer surgery times and a higher risk of acute kidney injury.
  • Overall, while prophylactic ureteral stents increased operative time and kidney issues, they did not significantly impact ureteral injuries, urinary infections, or other complications during colorectal surgery.
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