2 results match your criteria: "Federal State Budgetary Scientific Institution (East-Siberian Institute of Medical and Ecological Research)[Affiliation]"

Background: Thiodiacetic acid (TDAA) is the main metabolite of vinyl chloride (VC) and 1,2-dichloroethane (EDC) and its urinary level is correlated with the level of exposure to these chemicals.

Objective: To study dynamics of the excretion of TDAA into urine of polyvinyl chloride (PVC) production workers.

Methods: The study sample consisted of 65 workers of VC and PVC divisions with various time intervals following exposure to the chemicals, 10 shift workers from PVC division, and 34 workers not exposed to the chemicals (control group).

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The authors report the case of a lightning-fast course of amyotrophic lateral sclerosis (ALS) in a 49-year female patient. The diagnosis was based on complaints, clinical picture, electroneuromyography and tomography of the cervical spine. The nature of the course of the disease was fulminant, since 6 months passed from the onset of the first symptoms to the pronounced process, and then to the fatal outcome.

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